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This study aims to understand the epidemiological characteristics of SARS-CoV-2 infection in the paediatric population during the outbreak of the Omicron variant in Shanghai. We retrospectively analysed the population-based epidemiological characteristics and clinical outcome of SARS-CoV-2 Omicron variant infection in children in Minhang District, Shanghai, based on the citywide surveillance system during the outbreak period in 2022 (March to May). During this time, a total of 63,969 cases of SARS-CoV-2 infection were notified in Minhang District, out of which 4,652 (7.3%) were children and adolescents <18 years. The incidence rate of SARS-CoV-2 infections in children was 153 per 10,000. Of all paediatric cases, 50% reported to be clinically symptomatic within 1–3 days after PCR confirmation by parents or themselves, with 36.3% and 18.9% of paediatric cases reporting fever and cough. Also, 58.4% of paediatric cases had received at least one dose of the COVID-19 vaccine and 52.1% had received two doses of the COVID-19 vaccination. Our findings are informative for the implementation of appropriate measures to protect children from the threat of SARS-CoV-2 infection.
Dynamic interpersonal therapy (DIT) is a brief, structured psychodynamic psychotherapy with demonstrated efficacy in treating major depressive disorder (MDD). The aim of the study was to determine whether DIT is an acceptable and efficacious treatment for MDD patients in China.
Patients were randomized to 16-week treatments with either DIT plus antidepressant medication (DIT + ADM; n = 66), general supportive therapy plus antidepressant medication (GST + ADM; n = 75) or antidepressant medication alone (ADM; n = 70). The Hamilton Depression Rating Scale (HAMD) administered by blind raters was the primary efficacy measure. Assessments were completed during the acute 16-week treatment and up to 12-month posttreatment.
The group × time interaction was significant for the primary outcome HAMD (F = 2.900, df1 = 10, df2 = 774.72, p = 0.001) in the acute treatment phase. Pairwise comparisons showed a benefit of DIT + ADM over ADM at weeks 12 [least-squares (LS) mean difference = −3.161, p = 0.007] and 16 (LS mean difference = −3.237, p = 0.004). Because of the unexpected high attrition during the posttreatment follow-up phase, analyses of follow-up data were considered exploratory. Differences between DIT + ADM and ADM remained significant at the 1-, 6-, and 12-month follow-up (ps range from 0.001 to 0.027). DIT + ADM had no advantage over GST + ADM during the acute treatment phase. However, at the 12-month follow-up, patients who received DIT remained less depressed.
Acute treatment with DIT or GST in combination with ADM was similarly efficacious in reducing depressive symptoms and yielded a better outcome than ADM alone. DIT may provide MDD patients with long-term benefits in symptom improvement but results must be viewed with caution.
Phytoestrogens may have potential effects on hormone-related cancers (HRC) and cancer biomarkers, but the findings have been inconsistent so far. Participants from the National Health and Nutrition Examination Survey 1999–2010 with information on the levels of urinary phytoestrogens, serum cancer biomarkers and cancer history were included. Sampling-weighted logistic regression models examined the association between urinary phytoestrogens concentrations (creatinine-standardised and log-transformed) and HRC, followed by stratified analyses by race/ethnicity, age and menopausal status for different gender. Correlation analyses between phytoestrogens and cancer biomarkers were performed. Of the total 8844 participants, there were 373 with HRC. We observed total isoflavone and enterodiol excretion were positively associated with HRC, especially in non-Hispanic white female subpopulations (Ptrend < 0·05). Similar association also existed in the total isoflavones and enterodiol levels with breast cancer. Whereas the highest concentration of total isoflavones was significantly linked to a reduced prevalence of HRC (OR = 0·40, 95 % CI: 0·19, 0·84) in white males and of prostate cancer (OR = 0·40, 95 % CI: 0·18, 0·86). Among twenty-four participants with HRC, urinary equol concentration was positively correlated with CA15.3. Also, an inverse correlation of total prostate-specific antigens (PSA) and positive correlation of the PSA ratio with urinary enterolactone were detected in thirteen prostate cancer patients. Our findings indicated that higher concentrations of total isoflavones and enterodiol were positively associated with HRC. Urinary certain phytoestrogen excretion may affect serum cancer biomarker levels in cancer patients. But further prospective studies are needed to provide stronger evidence.
Recent years have witnessed a surge of management research on biology and affect (see Chapter 2 on the organizational neuroscience of emotions). An important reason is perhaps that management researchers have gradually realized the prominence of biological factors, including brain functions, hormones, and genetic factors, in modulating our attitudes and behaviors (e.g. Arvey, Li, & Wang, 2016; Arvey, Wang, Song, Li, & Day, 2014; Ashkanasy, Becker, & Waldman, 2014; Becker, Cropanzano, & Sanfey, 2011; Li, Stanek, Zhang, Ones, & McGue, 2016; Senior, Lee, & Butler, 2011; Waldman, Balthazard, & Peterson, 2011; Ward, Volk, & Becker, 2015). In this chapter, we will concentrate on the role of behavioral genetics and how this approach contributes to workplace affect. First, we will discuss the importance of behavioral genetics in fostering a more nuanced understanding of workplace affect. Second, we will review previous research, including both twin studies and molecular genetics research, on the influences of genetic factors on affect in the workplace, and we will selectively survey research on affect in general. Third, building upon recent research on behavioral genetics (Arvey & Bouchard, 1994; Arvey et al., 2016; Ilies, Arvey, & Bouchard, 2006; Li, Ilies, & Wang, 2017; Zyphur, Zhang, Barsky, & Li, 2013), affective events theory (AET) (Weiss & Beal, 2005; Weiss & Cropanzano, 1996), and personality development (Wrzus & Roberts, 2017), we will discuss an integral theoretical framework of workplace affect including influences from both genetic factors and environmental factors. We also offer some possible directions for future research.
Our study extends the relationship between paternalistic leadership and employee creativity by identifying employee organizational identification as a mediator and employee perceived job security as a moderator. Results based on the data of 378 employees from a large bank in China indicated that employee perceived job security moderated the relationship between the morality component of paternalistic leadership and employee creativity. In addition, employee organizational identification mediated the relationship between the morality component of paternalistic leadership and employee creativity. We discuss implications for research on paternalistic leadership and employee creativity.
Afghanite is a feldspathoid of the cancrinite-group: It is hexagonal, space group P63mc. The afghanite sample was found in the M. Somma-Vesuvio volcanic complex (Italy) and was previously described as davyne: Calculated cell parameters are a = 12.7997(4) Å, c = 21.4062(11) Å; the volume is 3037.2(2) Å3. The strongest lines are: 3.694(100), 3.647(56), 4.826(30), 2.678(25), 2.134(18), 3.999(12), 2.750(12), and 2.771(10). The new data provide quantitative measurement of intensities, an increased number of indexed peaks, and a different empirical formula with respect to the PDF 20-1086.
Improved powder X-ray diffraction (XRD) data for liottite and sacrofanite, two members of the cancrinite group of minerals, were obtained using a rotating anode diffractometer. The cell parameters of liottite are a = 12.8575(3), c = 16.0905(6) Å, and the space group is ; the strongest reflections are at 4.834(38), 3.783(12), 3.714(100), 3.312(91), 2.784(13), 2.682(26), 2.470(17), and 2.143(27) Å. The cell parameters of sacrofanite are a = 12.8945(4) and c =74.2128(37) Å, and the possible space groups are P63/mmc, P63mc, and ; the strongest reflections are at 11.18(23), 3.757(25), 3.723(100), 3.488(27), 3.302(62), 2.651(31), 2.645(30), and 2.149(18) Å. The new data include an increased number of indexed peaks and empirical formulae that differ from the reference data (PDF 29-1187 and PDF 35-653, respectively).