New zircon U–Pb ages and whole-rock chemical data from four adakitic and two non-adakitic igneous rocks as tectonic blocks in the southern West Junggar accretionary complexes, northwestern China and one gabbro enclave in adakitic block provide further constraints on the initial subduction and following rollback process of the Junggar Ocean as part of southern Palaeo-Asian Ocean. The oldest adakitic monzonite in Tangbale is intruded by the non-adakitic quartz monzonite at 549 Ma, and the youngest adakitic diorite in Tierekehuola formed at 520 Ma. The Ediacaran–Cambrian magmatism show a N-wards younger trend. The high-SiO2 adakitic rocks have high Sr (300–663 ppm) and low Y (6.68–12.2 ppm), with Sr/Y = 40–84 and Mg no. = 46–60, whereas the non-adakitic rocks have high Y (13.2–22.7 ppm) and Yb (2.32–2.92 ppm), with Mg no. = 36–40. The gabbro has high MgO (14.81–15.11 wt%), Co (45–48 ppm), Cr (1120–1360 ppm) and Ni (231–288 ppm), with Mg no. = 72–73. All the samples show similar large-ion lithophile element (LILE) and light rare earth element (LREE) enrichment and Nb, Ta, Ti and varying Zr and Hf depletion, suggesting that they were formed in a subduction-related setting. The adakitic rocks were produced by partial melting of subducted oceanic slab, but the melts were modified by mantle wedge and slab-derived fluids; the non-adakitic rocks were likely derived from partial melts of the middle-lower arc crust; and the gabbro originated from the mantle wedge modified by slab-derived fluids. The magmatism could have been generated during the Ediacaran initial subduction and Cambrian slab rollback of the Junggar Ocean.

Considerable research has been conducted on the advancement of mobile technologies to facilitate vocabulary learning and acquisition in a second language (L2). However, whether mobile platforms lead to a comprehensive mastery of both receptive and productive vocabulary knowledge has seldom been addressed in previous literature. This study investigated English vocabulary learning from engagement with mobile-based word cards and paper word cards in the context of the Chinese university classroom. A total of 85 undergraduate students were recruited to take part in the study. The students were divided into two groups, a mobile learning group and a paper-based learning group, and tested on two word knowledge components: receptive knowledge of the form–meaning connection and productive knowledge of collocations. Both the digital and non-digital word cards enhanced L2 vocabulary learning, and the results showed that the mobile application (app) promoted greater gains than physical word cards.

In this paper, a general method for synthesizing dispersive coupling matrix (DCM) of coupled-resonator bandpass filters with the general dispersion is proposed. Compared to the dispersion-less coupling matrix synthesized by classic approaches, the DCM incorporates the identity of the physical realization and provides an accurate description of the filter. Moreover, the DCM can accurately describe the complex resonators and coupling elements with intentional strong dispersion. A DCM consists of two parts: the frequency-invariant part that corresponds to the coupling matrix at the center frequency and the frequency-variant part that reflects the dispersion of the physical realization. By iteratively adjusting the transmission zeros governed by the given filter topology and ignoring the transmission zeros brought by the dispersion, the synthesis method can directly obtain the frequency-invariant part so that the overall DCM leads to an equal-ripple response. To illustrate the general synthesis method, two design examples are presented, which include a filter with unintentional weak dispersion and a filter with intentional strong dispersion. The examples are validated by EM simulation, demonstrating the effectiveness, accuracy, and generality of the proposed synthesis framework. Key words: dispersive coupling matrix, filter synthesis, microwave bandpass filter

Frozen embryo transfer (FET) has been adopted by growing number of reproductive medicine centers due to the improved outcome compared with fresh embryo transfer. However, few studies have focused on the impact of embryo cryopreservation duration on pregnancy-related complications and neonatal birthweight. Thus, a retrospective cohort study including all FET cycles with livebirth deliveries in a university affiliated hospital from May 2010 to September 2017 was conducted. These deliveries were grouped by the cryopreservation duration of the transferred embryo (≤3 months, 4–6 months, 7–12 months, and >12 months). The associations between embryo cryopreservation duration and pregnancy-related complications were evaluated among the groups using multinomial logistic regression. Neonatal birthweight was compared according to the stratification of singletons and multiples using multinomial and multilevel logistic regression, respectively. Among all 12,158 FET cycles, a total of 3864 livebirth deliveries comprising 2995 singletons and 1739 multiples were included. Compared with those within 3 months, women undergoing FET after a cryopreservation time longer than 3 months did not show any increased risk of gestational diabetes mellitus, gestational hypertension, preeclampsia, meconium staining of the amniotic fluid, or preterm birth. Furthermore, the risk of lower birthweight, macrosomia, small-for-gestational-age, or large-for-gestational-age for either singletons or multiples was not affected by long-term cryopreservation. In summary, embryo cryopreservation duration does not have negative effects on pregnancy-related complications or birthweight after FET.

Bacterial dysentery (BD) brings a major disease burden to developing countries. Exploring the influence of temperature and its interaction with other meteorological factors on BD is significant for the prevention and early warning of BD in the context of climate change. Daily BD cases and meteorological data from 2008 to 2018 were collected in all nine prefecture-level cities in Jilin Province. A one-stage province-level model and a two-stage city-specific multivariate meta-pooled level distributed lag non-linear model were established to explore the correlation between temperature and BD, then the weather-stratified generalised additive model was used to test the interaction. During the study period, a total of 26 971 cases of BD were developed. The one-stage and two-stage cumulative dose-response ‘J’ curves overlapped, and results showed a positive correlation between temperature and BD with a 1–6 days lag effect. Age group ⩾5 years was found to be more sensitive to the effects. Moreover, there was a significant interaction between temperature, humidity and precipitation (P = 0.004, 0.002, respectively) on BD under high temperature (>0 °C), reminding residents and policymakers to pay attention to the prevention of BD in situations with both high temperature and humidity, high temperature and precipitation during the temperate monsoon climate.

A closed Quaternary saline paleolake, currently still a lake and named Dalangtan after one of its largest sub-basins, has widely distributed sediments in the western Qaidam Basin, NE Tibetan Plateau. Lacustrine salt minerals and fine sediments from this paleolake provide an environmental record for investigating paleoclimatic evolution in the Asian interior. However, detailed continuous Pliocene–Quaternary paleoclimatic records are broadly lacking from the NE Tibetan Plateau owing to poor exposure of the outcrops in section. For this study, we performed a detailed magnetostratigraphic dating and rock magnetic analysis on a 590-m-long core from the SG-5 borehole in the western Qaidam Basin. The results demonstrate that the lacustrine sediments in the SG-5 borehole were deposited more than ~3.0 Ma. Saline minerals began to increase at 1.2 Ma, and the magnetic susceptibility (χ) also changed at that time; the percentage frequency-dependent magnetic susceptibility was relatively low and uniform throughout the whole core. These observations, combined with the χ, pollen, salt ion, and grain-size records from other boreholes, indicate that the western Qaidam Basin and the greater Asian interior had a significant climate transition at 1.2 Ma during an extreme drought.

Echinococcus shiquicus is currently limited to the Qinghai–Tibet plateau, a large mountainous region in China. Although the zoonotic potential remains unknown, progress is being made on the distribution and intermediate host range. In this study, we report E. shiquicus within Gansu and Qinghai provinces in regions located not only around the central areas but also the southeast edge of the plateau and describe their genetic relationship with previous isolates from the plateau. From 1879 plateau pikas examined, 2.39% (95% CI 1.79–3.18) were infected with E. shiquicus. The highest prevalence of 10.26% (4.06–23.58) was recorded in Makehe town, Qinghai province. Overall the prevalence was marginally higher in Qinghai (2.5%, CI 1.82–3.43) than in Gansu (2%, CI 1.02–3.89). The cox1 and nad1 genes demonstrated high and low haplotype and nucleotide diversities, respectively. The median-joining network constructed by the cox1–nad1 gene sequences demonstrated a star-like configuration with a median vector (unsampled haplotype) occupying the centre of the network. No peculiar distinction or common haplotype was observed in isolates originating from the different provinces. The presence of E. shiquicus in regions of the southeast and northeast edges of the Qinghai–Tibet plateau and high genetic variation warrants more investigation into the haplotype distribution and genetic polymorphism by exploring more informative DNA regions of the mitochondrial genome to provide epidemiologically useful insight into the population structure of E. shiquicus across the plateau and its axis.

Various studies suggest that the maritime industry will continue to face the challenge of seafarer shortages. Young seafarer turnover has become a serious issue that cannot be underestimated. This paper aims to identify the root causes of young seafarer attrition in China and explore relevant solutions. It collects information via semi-structured interviews and questionnaires. Independent sample t-test, one-way ANOVA and least-significant difference are utilised for the variance analysis. The findings of the study show that occupational recognition and family responsibility are the two major factors contributing to young seafarers’ outflow. Chinese seafarers’ health status is another important factor that has received little attention. In addition, young seafarers of 31–35 years old have the most possibility of turnover, due to a number of reasons discussed in this paper. Age 40 or thereabouts is viewed as the watershed moment in a seafarer's career, so efforts should be made to help young seafarers pass through the hard period in their early thirties. This paper suggests that a clear career plan could be a potential solution to retain this backbone group as prospective senior officers.

This paper develops second-order theory for narrow-banded surface gravity wavepackets experiencing a sudden depth transition based on a Stokes and multiple-scales expansion. As a wavepacket travels over a sudden depth transition, additional wavepackets are generated that propagate freely obeying the linear dispersion relation and arise at both first and second order in wave steepness in a Stokes expansion. In the region near the top of the depth transition, the resulting transient processes play a crucial role. At second order in wave steepness, free and bound waves coexist with different phases. Their different speeds of travel result in a local peak a certain distance after the depth transition. This distance depends on the water depth $h_s$ relative to the carrier wavelength on the shallower side $\lambda _{0s}$. We validate our theory through comparison with fully nonlinear numerical simulations. Experimental validation is provided in a companion paper (Li et al, J. Fluid Mech., 2021, 915, A72). We conjecture that the combination of the local transient peak at second order and the magnitude of the linear free waves provides the explanation for the rogue waves observed after a sudden depth transition reported in a significant number of papers and reviewed in Trulsen etal (J. Fluid Mech., vol. 882, 2020, R2).

Surface gravity wavepackets in intermediate water depth experiencing an abrupt depth decrease are investigated experimentally. The experiments provide validation for the second-order (in steepness) theory for narrow-banded surface gravity wavepackets experiencing a sudden depth transition derived in a companion paper (Li et al., J. Fluid Mech., 2021, 915, A71). We observe the generation of free second-order sub- and superharmonic wavepackets due to the sudden depth transition, in addition to changes to the main (first-order) wavepacket and its second-order bound waves. Locally, just after the step, this leads to the superposition of different wavepacket components. Thereafter, separation occurs because of the different group speeds of the free second-order sub- and superharmonic wavepackets compared with the main packet. Experiments show that the local superposition of waves can lead to significant amplification of wave crests near the top of a step, as predicted by theory. In addition to a step, we also experimentally examine more gradual depth changes in the form of 1 : 1 and 1 : 3 slopes to explore the limits of the theory's validity. Although we find small differences in amplitude and phase comparing these steep slopes with a step, these experiments suggest that the theoretical model derived in Part 1 for wavepackets travelling over a step is applicable to slopes steeper than $1\,{:}\,3$.

Calcification within breast cancer is a diagnostically significant radiological feature that generally consists of hydroxylapatite. Samples from 30 cases of breast carcinoma with calcification were investigated using optical microscopy, energy-dispersive X-ray analysis, transmission-electron microscopy, Fourier-transform infrared spectroscopy, Raman spectroscopy, synchrotron radiation X-ray diffraction and X-ray fluorescence. Under optical microscopy, the calcifications were found to consist of either irregular aggregates with widths > 200 μm or spherical aggregates similar to psammoma bodies with an average diameter of 30 μm. Transmission-electron microscopy showed that short columnar or dumbbell-shaped crystals with widths of 10–15 nm and lengths of 20–50 nm were the most common morphology; spherical aggregates (~1 μm in diameter) with amorphous coatings of fibrous nanocrystals were also observed. Results indicated that hydroxylapatite was the dominant mineral phase in the calcifications, and both CO32– and cation substitutions (Na, Mg, Zn, Fe, Sr, Cu and Mn) were present in the hydroxylapatite structure. Fourier-transform infrared spectra show peaks at 872 and 880 cm–1 indicating that CO32– substituted both the OH– (A type) and PO43– (B type) sites of hydroxylapatite, making it an A and B mixed type. The ratio of B- to A-type substitution was estimated in the range of 1.1–18.7 from the ratio of peak intensities (I872/I880), accompanied with CO32– contents from 1.1% to 14.5%. Trace arsenic, detected in situ by synchrotron radiation X-ray fluorescence was found to be distributed uniformly in the calcifications in the form of AsO43– substituting for PO43–. It is therefore proposed that identifying these trace elements in breast cancer calcifications may be promising for future clinical diagnostics.

The Dayao Paleolithic site, located in Inner Mongolia on the eastern margin of China's vast northwestern drylands, was a lithic quarry-workshop utilized by Pleistocene human migrants through the region. Determining the age of this activity has previously yielded controversial results. Our magnetostratigraphic and OSL dating results suggest the two artifact-bearing paleosols are correlated with MIS 5 and 7, respectively. Correlating paleoclimatic data with marine δ18O records leads us to conclude that two sandy gravel layers containing many artifacts in the lower part of the Dayao sequence were formed during MIS 9 and 11, if not earlier. Our results reveal that the earliest human occupation at the Dayao site occurred before ca. 400 ka during a relatively warm and moist interglacial period, similar to several subsequent occupations, documenting the earliest and northernmost archaeological assemblage yet reported in China's arid northwest. We conclude that the northward and southward displacements of the East Asian summer monsoon rain belt during past interglacial-glacial cycles were responsible for the discontinuous human occupation detected at the Dayao site. The penetration of this precipitation regime into dryland ecologies via the Huanghe (Yellow River) Valley effectively created a corridor for hominin migration into China's arid northwest.

As the remnant of the South Qilian Ocean, the South Qilian suture zone recorded abundant information on the Cambrian–Ordovician subduction history of the southern branch of the Proto-Tethyan Ocean. However, the closure timing of the South Qilian Ocean and subsequent collision are poorly constrained. In this study, we report early Silurian (433–435 Ma) U–Pb ages of felsic subvolcanic rocks from Lianhuashan, Ayishan and Shihuiyao of the Lajishan district within the South Qilian suture zone. They intruded the Late Ordovician – Silurian sedimentary or Late Ordovician volcanic rocks and have high SiO2 (61.43–73.06 wt%), Sr/Y ratios with significant different rare earth elements (REEs) and trace-element spider diagrams, and Sr–Nd isotopic compositions, probably implying that they were formed through distinctly different generation mechanisms. Geochemistry of the Lianhuashan dacites reveals compositions typical of adakitic rocks derived from partial melting of lower crust in a thickened setting. The Ayishan dacites were derived from partial melting of crustal materials with the involvement of minor peridotite mantle, and the Shihuiyao rhyolites were derived from partial melting of felsic crust. The similar geochemical characteristics of coeval post-collisional igneous rocks in the Central Qilian and South Qilian blocks indicates that the lower Silurian subvolcanic rocks were generated in a thickened crust of post-collisional setting. Considering their intrusive contacts with Late Ordovician – Silurian retro-foreland basin and Late Ordovician collisional volcanic rocks, we propose that the South Qilian suture zone was at a transitional stage from collisional to post-collisional during the early Silurian Period.

Beryl from Xuebaoding, Sichuan Province, western China is known for its unusual tabular habit and W–Sn–Be paragenesis in a greisen-type deposit. The crystals are typically colourless transparent to pale blue, often with screw dislocations of hexagonal symmetry on the (0001) crystal faces. Combining electron microprobe analyses and laser ablation inductively coupled plasma mass spectrometry with single-crystal X-ray diffraction (XRD), correlated with Raman and micro-infrared (IR) spectroscopy and imaging, the crystal chemical characteristics are determined. The contents of Na+ (0.24–0.38 atoms per formula unit (apfu)) and Li+ up to 0.38 apfu are at the high end compared to beryl from other localities worldwide. Li+ substitution for Be2+ on the tetrahedral (T2) site is predominantly charge balanced by Na+ on the smaller channel (C2) site, with Na+ ranging from 91.5% to 99.7% (apfu) of the sum of all other alkali elements. Cs+ and minor Rb+ and K+ primarily charge balance the minor M2+ substitution for Al3+ at the A site; all iron at the A site is suggested to be trivalent. The a axis ranges from 9.2161(2) to 9.2171(4) Å, with unit-cell volume from 678.03(3) to 678.48(7) Å3. The c/a ratio of 1.0002–1.0005 is characteristic for T2-type beryl with unit-cell parameters controlled primarily by Be2+ substitution. Transmission micro-IR vibrational spectroscopy and imaging identifies coordination of one or two water molecules to Na+ (type IIs and type IId, respectively) as well as alkali free water (type I). Based on IR absorption cross section and XRD a C1 site water content of 0.4–0.5 apfu is derived, i.e. close to 50% site occupancy. Secondary crystal phases with a decrease in Fe and Mg, yet increase in Na, suggest early crystallisation of aquamarine, with goshenite being late. With similar crystal chemistry to beryl of columnar habit from other localities worldwide, the tabular habit of Xuebaoding beryl seems to be unrelated to chemical composition and alkali content.

Manganese (Mn) oxides have been prevalent on Earth since before the Great Oxidation Event and the Mn cycle is one of the most important biogeochemical processes on the Earth's surface. In sunlit natural environments, the photochemistry of Mn oxides has been discovered to enable solar energy harvesting and conversion in both geological and biological systems. One of the most widespread Mn oxides is birnessite, which is a semiconducting layered mineral that actively drives Mn photochemical cycling in Nature. The oxygen-evolving centre in biological photosystem II (PSII) is also a Mn-cluster of Mn4CaO5, which transforms into a birnessite-like structure during the photocatalytic oxygen evolution process. This phenomenon draws the potential parallel of Mn-functioned photoreactions between the organic and inorganic world. The Mn photoredox cycling involves both the photo-oxidation of Mn(II) and the photoreductive dissolution of Mn(IV/III) oxides. In Nature, the occurrence of Mn(IV/III) photoreduction is usually accompanied with the oxidative degradation of natural organics. For Mn(II) oxidation into Mn oxides, mechanisms of biological catalysis mediated by microorganisms (such as Pseudomonas putida and Bacillus species) and abiotic photoreactions by semiconducting minerals or reactive oxygen species have both been proposed. In particular, anaerobic Mn(II) photo-oxidation processes have been demonstrated experimentally, which shed light on Mn oxide emergence before atmospheric oxygenation on Earth. This review provides a comprehensive and up-to-date elaboration of Mn oxide photoredox cycling in Nature, and gives brand-new insight into the photochemical properties of semiconducting Mn oxides widespread on the Earth's surface.