The effect of wall temperature on the transfer of kinetic energy in a hypersonic turbulent boundary layer for different Mach numbers and wall temperature ratios is studied by direct numerical simulation. A cold wall temperature can enhance the compressibility effect in the near-wall region through increasing the temperature gradient and wall heat flux. It is shown that the cold wall temperature enhances the local reverse transfer of kinetic energy from small scales to large scales, and suppresses the local direct transfer of kinetic energy from large scales to small scales. The average filtered spatial convection and average filtered viscous dissipation are dominant in the near-wall region, while the average subgrid-scale flux of kinetic energy achieves its peak value in the buffer layer. It is found that the wall can suppress the inter-scale transfer of kinetic energy, especially for the situation of a cold wall. A strong local reverse transfer of fluctuating kinetic energy is identified in the buffer layer in the inertial range. Helmholtz decomposition is applied to analyse the compressibility effect on the subgrid-scale flux of kinetic energy. A strong transfer of the solenoidal component of fluctuating kinetic energy is identified in the buffer layer, while a significant transfer of the dilatational component of fluctuating kinetic energy is observed in the near-wall region. It is also shown that compression motions have a major contribution to the direct transfer of fluctuating kinetic energy, while expansion motions play a marked role in the reverse transfer of fluctuating kinetic energy.

The Silurian and Devonian plant fossil record is the basis for our understanding of the early evolution of land plants, yet our appreciation of early global phytogeographic evolution has been constrained by the focus of most studies on deposits from Europe, North America, and, more recently, South China. Devonian plants have been recorded rarely from northeastern China, and among previous records, few plants have been illustrated and formally described. In this article, megafossil plants representing a Late Devonian-aged (probably Famennian) flora are described from a locality at northern Sonid Zuoqi, Inner Mongolia, NE China. The flora includes Melvillipteris sonidia new species, Archaeopteris sp., and fragments of some other plants. The new plant shows main axes and two orders of lateral branches. The first-order branches of this plant show a typical zigzag appearance and are borne in pairs on main axes. Second-order branches are straight or slightly flexed, and are borne helically or alternately on first-order branches. Sterile ultimate appendages and fertile structures of M. sonidia n. sp. are borne alternately on second-order branches. An associated palynological assemblage, as well as U-Pb ages of detrital zircon grains from adjacent horizons, are also reported, indicating a Late Devonian age in accord with the megafossil plants. The present study contributes to our appreciation of the Devonian floristic diversity of the Xing'an Block, and, through our review of the record of early vascular plants from NE China, more broadly to the understanding of the mid-latitude vegetation of the Northern Hemisphere during the Late Devonian.

Methomyl is a broad-spectrum carbamate insecticide that has a variety of toxic effects on humans and animals. However, there have been no studies on the toxicity of methomyl in female mammalian oocytes. This study investigated the toxic effects of environmental oestrogen methomyl exposure on mouse oocyte maturation and its possible mechanisms. Our results indicated that methomyl exposure inhibited polar body extrusion in mouse oocytes. Compared with that in the control group, in the methomyl treatment group, superoxide anion free radicals in oocytes were significantly increased. In addition, the mitochondrial membrane potential of metaphase II stage oocytes in the methomyl treatment group was significantly decreased, resulting in reduced mouse oocyte quality. After 8.5 h of exposure to methomyl, metaphase I stage mouse oocytes displayed an abnormal spindle morphology. mRNA expression of the pro-apoptotic genes Bax and Caspase-3 in methomyl-treated oocytes increased, which confirmed the apoptosis. Collectively, our results indicated that mouse oocyte maturation is defective after methomyl treatment at least through disruption of spindle morphology, mitochondrial function and by induction of oxidative stress.

A magnetically controlled spiral capsule robot is designed. When the robot is running in a pipe filled with mucus, computational fluid dynamics is used to analyze the fluid field (velocity, streamlines, and vorticity) in the pipe, and particle image velocimetry is used to measure the above fluid field surrounding the robot. The measured fluid field is basically similar to the numerical result. The relationship between the operating parameters of the robot and the performance of the robot is further calculated and analyzed. The results show that the resistance to the robot in the forward direction, average turbulent intensity of the fluid surrounding the robot, and maximum fluid pressure to the pipe wall are proportional to the robotic translational speed. The resisting moment of the robot in the forward direction, average turbulent intensity of the fluid surrounding the robot, and maximum fluid pressure to the pipe wall are proportional to the robotic rotational speed.

This paper first uses a decoupling modeling method to model legged robots. The method groups all the degrees of freedom according to the number of limbs, regarding each limb as a manipulator with serial structure, which greatly reduces the number of dynamic parameters that need to be identified simultaneously. On this basis, a step-by-step identification method from the end-effector link to the base link, referred to as “E-B” identification method, is proposed. Simulation verification is carried out on a quadruped robot with 16 degrees of freedom in Gazebo, and the validity of the method proposed is discussed.

Honeybees cannot synthesize arachidonic acid (ARA) themselves, only obtain it from food. Most pollen is deficient or contains a small amount of ARA. The necessity of supplementary ARA in bees’ diet has not been studied. The objective of this study was to investigate the effects of dietary ARA levels on the growth and immunity of Apis mellifera ligustica. A total of 25 honeybee colonies were randomly assigned to five dietary groups which were fed basic diets supplemented with 0, 2, 4, 6, and 8% of ARA. The diet with 4% ARA improved the body weight of newly emerged worker bees compared with the control group. Supplement of ARA in honeybee diets changed the fatty acid composition of honeybee body. SFA and MUFA contents of bees’ body declined, and PUFA content rised in the ARA group. Compared with the control group, the supplement of ARA in honeybee diets increased the contents of ARA, C22:6n-3 (DHA) and C18:3n-6 in bees’ body significantly, but decreased the contents of C16:1 and C18:3n-3. The diet supplied with 4% ARA reduced the mortality rate of honeybee infected with Escherichia coli. The activity of immune enzymes (phenoloxidase, antitrypsin, and lysozyme) and the mRNA expression levels of immune genes (defensin-2, toll, myd88, and dorsal) were improved by ARA diets to varying degrees depending on the ARA levels, especially 4% ARA. These results suggested that dietary ARA could improve the growth, survival, and immune functions of honeybees. Supplement of ARA in bees’ diet would be valuable for the fitness of honeybees.

As the corona virus disease 2019 (COVID-19) pandemic continues around the world, understanding the transmission characteristics of COVID-19 is vital for prevention and control. We conducted the first study aiming to estimate and compare the relative risk of secondary attack rates (SARs) of COVID-19 in different contact environments. Until 26 July 2021, epidemiological studies and cluster epidemic reports of COVID-19 were retrieved from SCI, Embase, PubMed, CNKI, Wanfang and CBM in English and Chinese, respectively. Relative risks (RRs) were estimated in pairwise comparisons of SARs between different contact environments using the frequentist NMA framework, and the ranking of risks in these environments was calculated using the surface under the cumulative ranking curve (SUCRA). Subgroup analysis was performed by regions. Thirty-two studies with 68 260 participants were identified. Compared with meal or gathering, transportation (RR 10.55, 95% confidence interval (CI) 1.43–77.85), medical care (RR 11.68, 95% CI 1.58–86.61) and work or study places (RR 10.15, 95% CI 1.40–73.38) had lower risk ratios for SARs. Overall, the SUCRA rankings from the highest to the lowest were household (95.3%), meal or gathering (81.4%), public places (58.9%), daily conversation (50.1%), transportation (30.8%), medical care (18.2%) and work or study places (15.3%). Household SARs were significantly higher than other environments in the subgroup of mainland China and sensitive analysis without small sample studies (<100). In light of the risks, stratified personal protection and public health measures need to be in place accordingly, so as close contacts categorising and management.

Different from developed countries, there is a paucity of research examining how the Dietary Approaches to Stop Hypertension (DASH) and Mediterranean diets relate to lipids in in less-developed ethnic minority regions (LEMRs). A total of 83,081 participants from seven ethnic groups were retrieved from the baseline data of the China Multi-Ethnic Cohort (CMEC) study, which was conducted in less-developed Southwest China between May 2018 and September 2019. Multivariable linear regression models were then used to examine the associations of the DASH and AMED scores, assessed by modified DASH score and alternative Mediterranean diet (AMED), as well as their components with total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG) and TC/HDL-C. The DASH scores were negatively associated with TC, HDL-C and TG. Comparing the highest quintiles with the lowest DASH scores, TC decreased 0.0708 (95% CI: −0.0923 ∼ −0.0493) mmol/L, HDL-C decreased 0.0380 (95% CI: −0.0462 ∼ −0.0299) mmol/L, and TG decreased 0.0668 (95% CI: −0.0994 ∼ −0.0341) mmol/L. The AMED scores were negatively associated with TC, LDL-C and HDL-C. Comparing the highest quintiles with the lowest AMED scores, TC decreased 0.0816 (95% CI: −0.1035 ∼ −0.0597) mmol/L, LDL-C decreased 0.0297 (95% CI: −0.0477 ∼ −0.0118) mmol/L, and HDL-C decreased 0.0275 (95% CI: −0.0358 ∼ −0.0192) mmol/L. Although both the DASH diet and the Mediterranean diet were negatively associated with blood lipids, those associations showed different patterns in LEMRs, particularly for TG and HDL-C.

Transient Marangoni convection induced by an isothermal sidewall of a rectangular pool under a zero-gravity condition is studied using scaling analysis. Scaling analysis shows that there exist a number of flow regimes in each evolution scenario, depending on the Marangoni number, the Prandtl number and the aspect ratio. In a typical evolution scenario, a horizontal surface flow and a vertical flow adjacent to the sidewall may appear. Additionally, a number of scaling laws of the velocity and thickness of transient Marangoni convection are obtained. Further, numerical simulation is performed for validation of the selected scaling laws. There exits good agreement between the numerical results and the scaling predictions.

In order to improve the speed of motion planning, this paper proposes an improved RRTConnect algorithm (SDPS-RRTConnect) based on sparse dead point saved strategy. Combining sparse expansion strategy and dead point saved strategy, the algorithm can reduce the number of collision detection, fast convergence, avoid falling into local minimum, and ensure the completeness of search space. The algorithm is simulated in different environments. The results show that in complex environments, the sparse dead point saved strategy plays a good effect. In simple environments, the greedy connection strategy works well. Compared with the standard RRT algorithm, the standard RRTConnect algorithm, and the SDPS-RRT algorithm, the SDPS-RRTConnect algorithm has the shortest planning time, and it is suitable for both simple and complex environments. The 500 experiments show that the algorithm has strong robustness. The actual robot experiments show that the path planned by SDPS-RRTConnect algorithm is effective.

Supercritical pressure fluids are widely used in heat transfer and energy systems. The benefit of high heat transfer performance and the successful avoidance of phase change from the use of supercritical pressure fluids are well-known, but the complex behaviours of such fluids owing to dramatic thermal property variations pose strong challenges to the design of heat transfer applications. In this paper, the turbulent flow and heat transfer of supercritical pressure $\textrm {CO}_2$ in a small vertical tube influenced by coupled effects of buoyancy and thermal acceleration are numerically investigated using direct numerical simulation. Both upward and downward flows with an inlet Reynolds number of 3540 and pressure of 7.75 MPa have been simulated and the results are compared with corresponding experimental data. The flow and heat transfer results reveal that under buoyancy and thermal acceleration, the turbulent flow and heat transfer exhibit four developing periods in which buoyancy and thermal acceleration alternately dominate. The results suggest a way to distinguish the dominant factor of heat transfer in different periods and a criterion for heat transfer degradation under the complex coupling of buoyancy and thermal acceleration. An analysis of the orthogonal decomposition and the generative mechanism of turbulent structures indicates that the flow acceleration induces a stretch-to-disrupt mechanism of coherent turbulent structures. The significant flow acceleration can destroy the three-dimensional flow structure and stretch the vortices resulting in dissipation.

Mental health problems are highly prevalent in China; however, China's mental health services lack resources to deliver high-quality care to people in need. Digital mental health is a promising solution to this short-fall in view of the population's digital literacy. In this review, we aim to: (i) investigate the effectiveness, acceptability, usability, and safety of digital health technologies (DHTs) for people with mental health problems in China; (ii) critically appraise the literature; and (iii) make recommendations for future research directions. The databases MEDLINE, PsycINFO, EMBASE, Web of Science, CNKI, WANFANG, and VIP were systemically searched for English and Chinese language articles evaluating DHTs for people with mental health problems in mainland China. Eligible studies were systematically reviewed. The heterogeneity of studies included precluded a meta-analysis. In total, 39 articles were retrieved, reporting on 32 DHTs for various mental health problems. Compared with the digital mental health field in the West, the Chinese studies targeted schizophrenia and substance use disorder more often and investigated social anxiety mediated by shame and culturally specific variants, DHTs were rarely developed in a co-production approach, and methodology quality was less rigorous. To our knowledge, this is the first systematic review focused on digital mental health in the Chinese context including studies published in both English and the Chinese language. DHTs were acceptable and usable among Chinese people with mental health problems in general, similar to findings from the West. Due to heterogeneity across studies and a paucity of robust control trial research, conclusions about the efficacy of DHTs are lacking.

Angiopoietin-like 4 (ANGPTL4) is a potent regulator of triacylglycerol metabolism but knowledge of the mechanisms underlying ANGPTL4 transcription in response to fatty acids is still limited in teleost. In this study, we explored the molecular characterization of ANGPTL4 and regulatory mechanisms of ANGPTL4 in response to fatty acids in large yellow croaker (Larimichthys crocea). Here, croaker angptl4 contained a 1416 bp open reading frame encoding a protein of 471 amino acids with highly conserved 12-amino acid consensus motif. Angptl4 was widely expressed in croaker, with the highest expression in the liver. In vitro, oleic and palmitic acids (OA and PA) treatments strongly increased angptl4 mRNA expression in croaker hepatocytes. Moreover, angptl4 expression was positively regulated by peroxisome proliferator-activated receptor family (PPAR-α, β and γ) and expression of pparγ was also significantly increased in response to OA and PA. Moreover, inhibition of PPARγ abrogated OA or PA-induced angptl4 mRNA expression. Beyond that, PA might increase angptl4 expression partly via the insulin signaling. Overall, the expression of ANGPTL4 is strongly upregulated by OA and PA via PPARγ in the liver of croaker, which contributes to improve the understanding of the regulatory mechanisms of ANGPTL4 in fish.

Entrepreneurs play a focal role in a society's economic recovery from major disruptions such as the COVID-19 pandemic. We argue that entrepreneurs’ ability to identify and act on entrepreneurial opportunities during the crisis reflects their resilience, and their innovations facilitate new patterns of work, learning, and leisure activities in post-COVID-19 societies. However, how, how quickly they act, and how influential their actions are depends on their context in terms of institutions, resource access, and market volatility. In China, some entrepreneurs have shown great resilience by utilizing network relationships and digital technology, not only to overcome short-term disruptions in 2020 but to shape the evolving ‘new normal’ where behaviors and capabilities have changed as a consequence of the experience of the pandemic. We discuss drivers of such resilient entrepreneurship during the COVID-19 pandemic in China and call for further research on the interplay between external disruptions, different types of entrepreneurship, and the consequences for resilience in emerging economies.

This article outlines the research progress on radiocarbon (14C) dating of the Erlitou site. The Erlitou site, belonging to the Bronze Age, located in Yanshi, Henan province, China, was discovered by archaeologists in 1959 when they investigated the Xia people’s remains in the area where the Xia people lived according to the records of ancient documents. Since then, there has been a standing debate about whether the site belongs to the Xia or Shang dynasty. By the mid-1990s, several hundred discussion articles on the issue had been published, but the question was still unresolved. Therefore, evidence from the chronology has attracted a great amount of attention. The dating of the Erlitou site began in the 1970s, and since the Xia-Shang-Zhou Chronology Project began in the mid-1990s, by application of wiggle-matching on the basis of improving the dating accuracy, the date of the Erlitou site has gradually become clear, which provides a basis for the archaeological research on the Xia and Shang dynasties.

Cross-waves are standing waves with crests perpendicular to a wave-maker; they are subharmonic waves excited by parametric instability. The modulational and chaotic behaviours of nonlinear cross-waves have been studied widely since the 1970s. Most of the previous work has focused on gravity waves where surface tension can be neglected. In this work we study cross-waves that are highly dependent on surface tension as well as gravity. By oscillating a planar wave-maker either vertically or horizontally with frequencies of 25 Hz through 40 Hz at one end of a rectangular basin, two-dimensional multi-component surface patterns are realized. Using the free-surface synthetic Schlieren technique to measure the surface elevations, multi-dimensional Fourier transforms are utilized to track the evolutionary spectrum of the water surface in both the temporal and spatial domains. Wavelet transforms are implemented to show the development of the various frequency components. Three-wave resonances with and without first subharmonics are observed for small nonlinearity. Three-dimensional oblique propagating cross-waves are generated at higher nonlinearity; unlike most previous cross-wave experiments, this staggered pattern propagates far downstream. Experimental evidence shows that two oblique propagating waves form a two-dimensional short-crested pattern, and that the lateral component of the waves develops into parametric sloshing modes corresponding to the width of the tank. Two regimes of nonlinear wave patterns, resonant triads and oblique propagating cross-waves, are delineated.