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4 results

  • 13 - Circadian rhythm dysregulation in the elderly: shift work

  • from Part 3 - Sleepdisorders in the elderly
  • Edited by S. R. Pandi-Perumal, Jaime M. Monti, Universidad de la República, Uruguay, Andrew A. Monjan, National Institute on Aging, Bethesda, Maryland
  • Book:
    Principles and Practice of Geriatric Sleep Medicine
    Published online:
    04 August 2010
    Print publication:
    26 November 2009, pp 143-149

  • Summary

    This chapter presents the factors relevant to assessing sleep problems in the menopausal transition that have changed over time. Expectations regarding menopause have changed over time, particularly since the advent of hormone replacement therapy. Increasing interest in reproductive aging and the advent of women's health as a specialty has led to a great deal of research on the menopausal transition. It is possible that there has been an increase in sleep disturbances in women across all menopausal status categories, but that the rank order of increasing prevalence of sleep problems among pre-, peri-, and post-menopausal women prevails. Preliminary analyses from the "Sleep in Midlife Woman" sub study, with biannual in-home polysomnography, continue to support the hypothesis that the risk of sleep apnea increases with advancement through the menopausal transition. There are important clinical implications from current thinking on sleep in the menopausal transition.

  • The effects of age and gender on sleep EEG power spectral density in the middle years of life (ages 20–60 years old)

  • JULIE CARRIER, STEPHANIE LAND, DANIEL J. BUYSSE, DAVID J. KUPFER, TIMOTHY H. MONK
  • Journal:
    Psychophysiology / Volume 38 / Issue 2 / March 2001
    Published online by Cambridge University Press:
    02 March 2001, pp. 232-242
    Print publication:
    March 2001

  • The effects of age and gender on sleep EEG power spectral density were assessed in a group of 100 subjects aged 20 to 60 years. We propose a new statistical strategy (mixed-model using fixed-knot regression splines) to analyze quantitative EEG measures. The effect of gender varied according to frequency, but no interactions emerged between age and gender, suggesting that the aging process does not differentially influence men and women. Women had higher power density than men in delta, theta, low alpha, and high spindle frequency range. The effect of age varied according to frequency and across the night. The decrease in power with age was not restricted to slow-wave activity, but also included theta and sigma activity. With increasing age, the attenuation over the night in power density between 1.25 and 8.00 Hz diminished, and the rise in power between 12.25 and 14.00 Hz across the night decreased. Increasing age was associated with higher power in the beta range. These results suggest that increasing age may be related to an attenuation of homeostatic sleep pressure and to an increase in cortical activation during sleep.