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3 results

  • Pulvinar Sign in Wernicke's Encephalopathy

  • Christian Schmidt, Steffen Plickert, David Summers, Inga Zerr
  • Journal: CNS Spectrums / Volume 15 / Issue 4 / April 2010
  • Published online by Cambridge University Press: 07 November 2014, pp. 215-219
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  • Case 23 - Thiamine for dementia in a young woman

  • Edited by Serge Gauthier, McGill University, Montréal, Pedro Rosa-Neto, McGill University, Montréal
  • Book: Case Studies in Dementia
  • Published online: 16 May 2011
  • Print publication: 21 April 2011, pp 172-179

  • Summary

    This chapter talks about a 50-year-old man who was referred for dementia evaluation a few months after losing his job as head of a department in a large company. An MRI scan was initially described with white matter lesions in the temporal and parietal lobes, but no focal atrophy. A revised report also described cortical atrophy of the frontal lobes. The diagnosis of the Frontotemporal Dementia (FTD) was given based on the dominant clinical symptoms that had developed gradually over a couple of years: apathy, disinhibition, loss of social conduct, impaired empathy, stereotypic behavior, neglect of self-care, altered eating pattern, and impaired insight. Frontotemporal Lobar Degeneration (FTLD) is used here as the general label for neurodegenerative diseases involving primarily the anterior regions of the brain. The patient presented here is a prototypical example of the behavioral variant of FTLD, exhibiting most of the characteristic features of this clinical subtype.