This chapter engages with ‘legacy’ in two respects. It argues that Article 15 of the International Covenant on Economic, Social and Cultural Rights (ICESCR), the so-called right to science, has no legacy. It has achieved only marginal real-world impact and remains largely aspirational – all potential. By contrast, Graeme Laurie’s legacy, grounded in the public good and a strong sense of humanism, is significant and informative. Through multiple strands and projects, he has engaged deeply with the social contract between actors in the health setting, developing and refining the tools that could be used to help shape science and science governance in positive ways. Through an exploration of Article 15 ICESCR and select examples of Graeme’s scholarship, this chapter argues that the manifestation of Graeme’s legacy – the calling upon of his legacy – is what we need to generate some positive legacy for the sadly fallow ‘right to science’ articulated in Article 15 ICESCR. If we do this, it might one day have a legacy of its own.

This chapter considers how technological innovations represent disturbances with which regulatory frameworks must cope, focusing on innovations that can be characterised as ‘enhancing’. Human enhancement can no longer be dismissed as something with which serious regulatory frameworks need not engage. Enhancing pursuits increasingly occupy the very centre of human experience and ‘being’; one can observe widespread student use of cognitively enhancing stimulants, the increasing prevalence of implanted technologies, and great swathes of people absently navigating the physical while engrossed in the digital. The medical devices framework, one might think, should offer a good example of a regime that engages directly and usefully with the concepts implicated by enhancement and the socio-technical changes wrought by enhancing technologies. As such, this chapter focuses on the recently reformed medical devices framework. After identifying some enhancements that are available and highlighting what they mean for the person, the chapter introduces two concepts that are deeply implicated by enhancing technologies: ‘identity’ and ‘integrity’. If regulation fails to engage with them, it will remain blind to matters that are profoundly important to those people who are using or relying on these technologies.