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1 results

  • Recurring déjà vu associated with 5-hydroxytryptophan
  • Seema Kalra, Andrew Chancellor, Adam Zeman
  • Journal: Acta Neuropsychiatrica / Volume 19 / Issue 5 / October 2007
  • Published online by Cambridge University Press: 24 June 2014, pp. 311-313
  • View abstract
    Background:

    Déjà vu occurs both in normal experience and as a neuropsychiatric symptom. Its pathogenesis is partially understood. We describe an iatrogenic case with implications for the neuropharmacological basis of déjà vu.

    Case presentation:

    A 42-year-old woman received 5-hydroxytryptophan, in combination with carbidopa, as treatment for palatal tremor, on two occasions, separated by 1 week. On each occasion, she experienced intense, protracted déjà vu, lasting for several hours. We discuss her case in relation to the neuroanatomical and neuropharmacological basis of déjà vu.

    Conclusion:

    The serotonergic system is involved in the genesis of déjà vu.