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This chapter focuses on the concept of patient consent for ansthesia for psychosurgery and electroconvulsive therapy (ECT) using the case of a 20-year-old patient with severe psychiatric disorders. Psychosurgery has a controversial history, in which medical, moral, social, and political considerations intermingle. The main ethical issues connected to these interventions involve the scientific validity of the therapy and its evaluation, the validity of patient consent, and the possibility of conflict between the interests of the patient and those of society, particularly in the case of dangerous or violent individuals. Psychosurgery raises fundamental questions, such as those linked to the definition of person and free will, concepts of dignity, integrity, and the validity of true consent. Ultimately, decisions regarding psychosurgical interventions and ECT must be made on a case-by-case basis, taking into account patient suffering and disability, and balancing these considerations with patient autonomy.