The interplay between convective, rotational and magnetic forces defines the dynamics within the electrically conducting regions of planets and stars. Yet their triadic effects are separated from one another in most studies, arguably due to the richness of each subset. In a single laboratory experiment, we apply a fixed heat flux, two different magnetic field strengths and one rotation rate, allowing us to chart a continuous path through Rayleigh–Bénard convection (RBC), two regimes of magnetoconvection, rotating convection and two regimes of rotating magnetoconvection, before finishing back at RBC. Dynamically rapid transitions are determined to exist between jump rope vortex states, thermoelectrically driven magnetoprecessional modes, mixed wall- and oscillatory-mode rotating convection and a novel magnetostrophic wall mode. Thus, our laboratory ‘pub crawl’ provides a coherent intercomparison of the broadly varying responses arising as a function of the magnetorotational forces imposed on a liquid-metal convection system.

Introduction: Adoption of a new Electronic Health Record (EHR) can introduce radical changes in task allocation, work processes, and efficiency for providers. In June 2019, The Ottawa Hospital transitioned from a primarily paper based EHR to a comprehensive EHR (Epic) using a “big bang” approach. The objective of this study was to assess the impact of the transition to Epic on Emergency Physician (EP) work activities in a tertiary care academic Emergency Department (ED). Methods: We conducted a time motion study of EPs on shift in low acuity areas of our ED (CTAS 3-5). Fifteen EPs representing a spectrum of pre-Epic baseline workflow efficiencies were directly observed in real-time during two 4-hour sessions prior to EHR implementation (May 2019) and again in go live (August 2019). Trained observers performed continuous observation and measured times for the following EP tasks: chart review, direct patient care, documentation, physical movement, communication, teaching, handover, and other (including breaks). We compared time spent on tasks pre Epic and during go live and report mean times for the EP tasks per patient and per shift using two tailed t-test for comparison. Results: All physicians had a 17% decrease in patients seen after Epic implementation (2.72/hr vs 2.24/hr, p < 0.01). EPs spent the same amount of time per patient on direct patient care and chart review (direct patient care: 9min06sec/pt pre vs 8min56sec/pt go live, p = 0.77; chart review: 2min47sec/pt pre vs 2min50sec/pt go live, p = 0.88), however, documentation time increased (5min28sec/pt pre vs 7min12sec/pt go live, p < 0.01). Time spent on shift teaching learners increased but did not reach statistical significance (31min26sec/shift pre vs 36min21sec/shift go live, p = 0.39), and time spent on non-patient-specific activities – physical movement, handover, team communication, and other – did not change (50min49sec/shift pre vs 50min53sec/shift go live, p = 0.99). Conclusion: Implementation of Epic did not affect EP time with individual patients - there was no change in direct patient care or chart review. Documentation time increased and EP efficiency (patients seen per hr on shift) decreased after go live. Patient volumes cannot be adjusted in the ED therefore anticipating the EHR impact on EP workflow is critical for successful implementation. EDs may consider up staffing 20% during go live. Findings from this study can inform how to best support EDs nationally through transition to EHR.

Sheath blight caused by soil borne necrotrophic fungus Rhizoctonia solani [teleomorph-Thanatephorus cucumeris (Frank) Donk.] is a major disease of rice. The disease is increasing over the year in India and cause up to 69% yield loss under favourable conditions. A total of 67 accessions of Oryza nivara were screened to identify resistance against sheath blight during 2015. Out of these, 16 accessions were found moderately resistant (MR) which were further evaluated during the year 2016 and 2017. After three years of screening, 12 of them were found to have a consistent moderate resistant reaction whereas four of the O. nivara accessions namely, IRGC81941, IRGC102463C, CR100097 and CR100110A have shown moderately susceptible to susceptible reaction against sheath blight. A correlation study revealed that different disease variables measured were significantly (P < 0.05) correlated. All the genotypes and genotype × environment interaction had a significant (P < 0.001) effect on all the disease variables. Cluster analysis showed that all the accessions were clustered into four groups which showed resistant, MR, moderately susceptible and susceptible reactions. Among all the O. nivara accessions IRGC81941A showed the maximum potential against sheath blight due to a least relative lesion height of 22.80%. None of the accession had complete resistance to the disease. The identified promising accessions such as IRGC81835, IRGC81941A, CR100008 and CR100111B can be utilized in a sheath blight resistance breeding program.

Source–sink balance was studied by imposing different canopy defoliation treatments on wheat crops grown in Los Banos (Philippines) in 1985/86 and 1986/87, Sonora (Mexico) in 1972/73 and 1974/75 and New Delhi (India) in 1987/88. The crops were grown in replicated trials with optimum cultural management. Six defoliation treatments were imposed at anthesis on all shoots in the canopy in an area ranging between 1·65 and 3·0 m2. Defoliation reduced dry weight in proportion to the reduction in percentage light interception. The number of grains per unit land area was reduced slightly, and in most cases not significantly, except when all leaves were removed. Despite reduction of leaf lamina area index to as low as 0·5, the decrease in grain yield was small. In particular, flag leaf removal led to a remarkably small reduction in grain yield. Grain nitrogen content in defoliated crops decreased much less than expected from the amount of N removed by defoliation. The slope of the relation between reduction in grain yield with defoliation and reduction in post-anthesis dry matter accumulation was 0·56, indicating moderate source limitation for grain filling. The crops at the hottest site, in the Philippines, were less limited by source than the other crops. It is suggested that selection for smaller flag leaves may be worthwhile for high-input wheat crops.

Cowpea is an important food legume crop of arid and semi-arid regions of the tropics. In such climates whether a determinate or indeterminate type of growth habit would be more useful is not clear. In the present study a determinate and indeterminate cultivar of cowpea were grown at two population densities under rainfed conditions for 2 years. Grain yield was higher in the indeterminate variety for both years. At higher density more dry matter was produced but it had no effect on grain yield. Nitrogen analysis showed that it moved from leaves to developing pods. However, a large amount of nitrogen was still left in vegetative parts in contrast to cereals. Pod development was completed in 19 days and the rate of dry-matter accumulation during the peak period of growth was as high as 120 mg/day per fruit. It was difficult for the plant to cope with this high demand for photosynthates. It is suggested that more pods can develop on a plant provided the growth rate of individual pods is slower and extended to a longer period.

The Indian subcontinent has witnessed a spectacular improvement in yield of wheat during the past decade (Rao, 1978). This is reflected in the improvement of the average national yields as well as of those regions where wheat is grown as an irrigated crop (Sinha & Aggarwal, 1981). However, after the release of the double dwarf variety Kalyansona, only marginal improvement in yield has occurred in recent years. Despite this, the semi-dwarf character continues to be considered a major factor for improvement of wheat. Asana & Chattopadhyay (1970), Konar & Asana (1975), and Wattal & Asana (1976) observed no significant difference in yield between tall and semi-dwarf (medium tall) varieties in pot culture experiments where lodging was prevented and competition was partly reduced. They ascribed prevention from lodging and improvement in the ratio of grain to total above-ground dry matter as major advantages in the modern varieties. Somewhat similar conclusions have recently been drawn by Austin et al. (1980). However, a detailed comparison of various physiological and biochemical characters lias not been made to determine whether any advance has occurred in basic processes such as photosynthesis and nitrogen assimilation. The present study was an effort in this direction.

Fourteen strains of S. Typhi (n=13) and S. Paratyphi A (n=1) resistant to ciprofloxacin were compared with 30 ciprofloxacin decreased-susceptibility strains on the basis of qnr plasmid analysis, and nucleotide substitutions at gyrA, gyrB, parC and parE. In ciprofloxacin-resistant strains, five S. Typhi and a single S. Paratyphi A showed triple mutations in gyrA (Ser83→Phe, Asp87→Asn, Glu133→Gly) and a novel mutation outside the quinolone resistance determining region (QRDR) (Met52→Leu). Novel mutations were also discovered in an isolate (minimum inhibitory concentration 8 μg/ml) in gyrA gene Asp76→Asn and outside the QRDR Leu44→Ile. Out of 30 isolates with reduced susceptibility, single mutation was found in 12 strains only. Genes encoding qnr plasmid (qnr A, qnr B, AAC1-F) were not detected in ciprofloxacin-resistant or decreased-susceptibility strains. Antimicrobial surveillance coupled with molecular analysis of fluoroquinolone resistance is warranted for reconfirming novel and established molecular patterns of resistance, which is quintessential for reappraisal of enteric fever therapeutics.

Elongated styloid process is a relatively common cause of facial and neck pain, but it is often misdiagnosed due to its varied clinical presentation. Since an elongated styloid process is often confirmed by radiological means, it would be helpful to find a more accurate mode of depicting the styloid process.

In this prospective study, 39 cases were evaluated. A three-dimensional computed tomography (3D CT) reconstruction of the styloid process was performed in 18 cases. In these patients, we compared the length and medial angulation of the symptomatic styloid process as viewed on an orthopantomogram and a 3D CT reconstruction.

It was noted that a 3D CT reconstruction was more accurate in depicting the styloid process. This investigation can be considered as the ‘gold standard’ in the radiological diagnosis of an elongated styloid process.

There is marked diversity in the reported success rates for achieving an intact tympanic membrane following myringoplasty. Controversy exists about the factors thought to influence surgical outcome. Both of these facts have important implications for obtaining informed consent prior to surgery.

This study reviews the factors thought to determine the likelihood of achieving complete closure of the tympanic membrane following surgical closure.

Cisplatin (cw-diamminedichloroplatinum II; CDDP) is a broad spectrum anti-cancer agent with severe toxic side effects. New platinum based chemotherapeutic agents with similar properties are in constant development. Poly-plat (Poly-[(teans-l,2-diaminocyclohexane) platinum]-carboxyamylose), a novel second generation platinum chemotherapeutic agent, has been shown to be less toxic compared to CDDP. The purpose of this paper was to examine the morphological changes in the Kupffer cells in the liver after poly-plat treatment in rats and compare the results obtained after CDDP. Peripheral blood was also examined for levels of circulating leukocytes.

Wistar rats (120-160 g) were given intraperitoneal injections of either CDDP (9 mg/kg in 0.9% sodium chloride) or poly-plat (10 mg/kg in 0.9% sodium chloride) over a five day period. Controls were treated with equal amounts of the vehicle of injection. Peripheral blood was collected via tail vein beginning 1 day prior to treatment and continuing 10 days after treatment.

Cisplatin, a commonly used broad spectrum chemotherapeutic drug, has been proven effective in the treatments of bladder, lung, ovarian, head and neck, testicular and breast cancers. One of the major side effects of this drug is its gastrointestinal toxicity, which includes severe nausea, vomiting and in case of rats bloating of the stomach and gastric ulceration. In case of rats, it manifests as bloating of the stomach and gastric ulceration since the rats don't have vomiting reflex. This has been attributed to hypocalcemia induced by cisplatin treatment which results in the suppression of acetylcholine and constitutive nitric oxide release inducing a bloating of the stomach. This has further been shown to induce an increase in the acid content of the stomach. There are no studies available on any changes of gastric protection after cisplatin treatment Gastrin has been shown to have gastroprotective effects against injury by maintaining the gastric mucosal integrity and gastric mucosal blood flow.

Comments have been frequently made on the differences in the symptomatological pattern of depression in different cultural groups. Kraepelin (1921), in his study on the incidence of depressive illness in Asian countries, mentioned that depression in Java was characterized almost exclusively by excitement and confusion and that ideas of sin and suicidal tendencies were absent. Carothers (1958) could not elicit feelings of guilt or self abasement in depression among the Africans of Kenya. Lambo (1956), of Nigeria, thought that the rarity of depression observed by many workers in African countries might be due to erroneous diagnosis, and that most of the cases remain concealed by the label of ‘neurasthenia’. Out of fifteen cases of definite affective psychosis seen by him only one showed guilt feelings, self-condemnation and anticipation of punishment. Multiple somatic features, phobic and obsessional symptoms and anxiety were common. Yap (1965), commenting on the findings of various workers about depression in African countries, states ‘there is agreement among these authors on the rarity of outspoken affective illness, lightness and short duration of depression with an absence of ideas of sin and guilt, the relative frequency of manic pictures, the common association with confusional symptoms, and a very low suicide rate.’ He also refers to Pfeiffer's findings about the frequency of hypochondriacal depression in the Chinese. The absence of delusions of sin in Chinese as well as in Japanese depressives has also been noted by Yap (1958). On the other hand, Eaton and Weil (1955), in a study concerning the Hutterites, have reported a high incidence of guilt-ridden depression.