In this work, different set-ups as well as different transducer materials have been investigated in order to develop a hydrogen peroxide (H2O2) sensor for the gas phase. The sensor is based on a combined physical/chemical transduction mechanism and should be able to detect high H2O2 concentrations up to 10 Vol.%. Different sensor arrangements are presented that are based on a “three sensor” cell and a diffusion cell. As transducer materials manganese oxide and copper alloys have been investigated. For the reference part of the sensor set-up, Teflon and enamel have been tested as passivating material.