We study the statistics of passive scalars at $Pr=1$, for turbulent flow within a smooth straight pipe of circular cross section up to $Re_{\tau } \approx 6000$ using direct numerical simulation (DNS) of the Navier–Stokes equations. While featuring a general organisation similar to the axial velocity field, passive scalar fields show additional energy at small wavenumbers, resulting in a higher degree of mixing and in a $k^{-4/3}$ spectral inertial range. The DNS results highlight logarithmic growth of the inner-scaled bulk and mean centreline scalar values with the friction Reynolds number, implying an estimated scalar von Kármán constant $k_{\theta } \approx 0.459$, which also nicely fits the mean scalar profiles. The DNS data are used to synthesise a modified form of the classical predictive formula of Kader & Yaglom (Intl J. Heat Mass Transfer, vol. 15 (12), 1972, pp. 2329–2351), which points to some shortcomings of the original formulation. Universality of the mean core scalar profile in defect form is recovered, with very nearly parabolic shape. Logarithmic growth of the buffer-layer peak of the scalar variance is found in the Reynolds number range under scrutiny, which well conforms with Townsend's attached-eddy hypothesis, whose validity is also supported by the spectral maps. The behaviour of the turbulent Prandtl number shows good universality in the outer wall layer, with values $Pr_t \approx 0.84$, as also found in previous studies, but closer to unity near the wall, where existing correlations do not reproduce the observed trends.

We study turbulent flows in a smooth straight pipe of circular cross-section up to friction Reynolds number $({\textit {Re}}_{\tau }) \approx 6000$ using direct numerical simulation (DNS) of the Navier–Stokes equations. The DNS results highlight systematic deviations from Prandtl friction law, amounting to approximately $2\,\%$, which would extrapolate to approximately $4\,\%$ at extreme Reynolds numbers. Data fitting of the DNS friction coefficient yields an estimated von Kármán constant $k \approx 0.387$, which nicely fits the mean velocity profile, and which supports universality of canonical wall-bounded flows. The same constant also applies to the pipe centreline velocity, thus providing support for the claim that the asymptotic state of pipe flow at extreme Reynolds numbers should be plug flow. At the Reynolds numbers under scrutiny, no evidence for saturation of the logarithmic growth of the inner peak of the axial velocity variance is found. Although no outer peak of the velocity variance directly emerges in our DNS, we provide strong evidence that it should appear at ${\textit {Re}}_{\tau } \gtrsim 10^4$, as a result of turbulence production exceeding dissipation over a large part of the outer wall layer, thus invalidating the classical equilibrium hypothesis.

Functional circuits of the human brain emerge and change dramatically over the second half of gestation. It is possible that variation in neural functional system connectivity in utero predicts individual differences in infant behavioral development, but this possibility has yet to be examined. The current study examines the association between fetal sensorimotor brain system functional connectivity and infant postnatal motor ability. Resting-state functional connectivity data was obtained in 96 healthy human fetuses during the second and third trimesters of pregnancy. Infant motor ability was measured 7 months after birth using the Bayley Scales of Infant Development. Increased connectivity between the emerging motor network and regions of the prefrontal cortex, temporal lobes, posterior cingulate, and supplementary motor regions was observed in infants that showed more mature motor functions. In addition, females demonstrated stronger fetal-brain to infant-behavior associations. These observations extend prior longitudinal research back into prenatal brain development and raise exciting new ideas about the advent of risk and the ontogeny of early sex differences.

Deficits in facial affect recognition have been repeatedly reported in schizophrenia patients. The hypothesis that this deficit is caused by poorly differentiated cognitive representation of facial expressions was tested in this study. To this end, performance of patients with schizophrenia and controls was compared in a new emotion-rating task. This novel approach allowed the participants to rate each facial expression at different times in terms of different emotion labels. Results revealed that patients tended to give higher ratings to emotion labels that did not correspond to the portrayed emotion, especially in the case of negative facial expressions (p < .001, η2 = .131). Although patients and controls gave similar ratings when the emotion label matched with the facial expression, patients gave higher ratings on trials with "incorrect" emotion labels (ps < .05). Comparison of patients and controls in a summary index of expressive ambiguity showed that patients perceived angry, fearful and happy faces as more emotionally ambiguous than did the controls (p < .001, η2 = .135). These results are consistent with the idea that the cognitive representation of emotional expressions in schizophrenia is characterized by less clear boundaries and a less close correspondence between facial configurations and emotional states.

We use the Bolshoi Simulation to find the most probable location of the Local Group (LG) in the cosmic web. Our LG simulacra are pairs of halos with isolation and kinematic properties consistent with observations. The cosmic web is defined using a tidal tensor approach. We find that the LG's preferred location is regions with a dark matter overdensity close to the cosmic average. This makes filaments and sheets the preferred environment. We also find a strong alignment between the LG and the cosmic web. The orbital angular momentum is preferentially perpendicular to the smallest tidal eigenvector, while the vector connecting the two halos is strongly aligned along the the smallest tidal eigenvector and perpendicular to the largest tidal eigenvector; the pair lies and moves along filaments and sheets. We do not find any evidence for an alignment between the spin of each halo in the pair and the cosmic web.

The Center for Epidemiologic Studies-Depression Scale (CES-D) is the most frequently used scale for measuring depressive symptomatology in caregiving research. The aim of this study is to test its construct structure and measurement equivalence between caregivers from two Spanish-speaking countries. Face-to-face interviews were carried out with 595 female dementia caregivers from Madrid, Spain, and from Coahuila, Mexico. The structure of the CES-D was analyzed using exploratory and confirmatory factor analysis (EFA and CFA, respectively). Measurement invariance across samples was analyzed comparing a baseline model with a more restrictive model. Significant differences between means were found for 7 items. The results of the EFA clearly supported a four-factor solution. The CFA for the whole sample with the four factors revealed high and statistically significant loading coefficients for all items (except item number 4). When equality constraints were imposed to test for the invariance between countries, the change in chi-square was significant, indicating that complete invariance could not be assumed. Significant between-countries differences were found for three of the four latent factor mean scores. Although the results provide general support for the original four-factor structure, caution should be exercised on reporting comparisons of depression scores between Spanish-speaking countries.