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This is the first report on the association between trauma exposure and depression from the Advancing Understanding of RecOvery afteR traumA(AURORA) multisite longitudinal study of adverse post-traumatic neuropsychiatric sequelae (APNS) among participants seeking emergency department (ED) treatment in the aftermath of a traumatic life experience.
We focus on participants presenting at EDs after a motor vehicle collision (MVC), which characterizes most AURORA participants, and examine associations of participant socio-demographics and MVC characteristics with 8-week depression as mediated through peritraumatic symptoms and 2-week depression.
Eight-week depression prevalence was relatively high (27.8%) and associated with several MVC characteristics (being passenger v. driver; injuries to other people). Peritraumatic distress was associated with 2-week but not 8-week depression. Most of these associations held when controlling for peritraumatic symptoms and, to a lesser degree, depressive symptoms at 2-weeks post-trauma.
These observations, coupled with substantial variation in the relative strength of the mediating pathways across predictors, raises the possibility of diverse and potentially complex underlying biological and psychological processes that remain to be elucidated in more in-depth analyses of the rich and evolving AURORA database to find new targets for intervention and new tools for risk-based stratification following trauma exposure.
Clinical Obsessive-Compulsive Disorders in Adults and Children is a complete, comprehensive overview of OCD, covering its underlying causes, manifestations and treatment. The book begins by covering the basic science of OCD and its biological basis and mechanisms. It discusses the treatment for both adults and children with an emphasis on providing information for clinicians to use in their everyday practice. Using the latest information regarding evidence-based treatments, it takes the reader through medication options, including behavioural therapy, support groups and recent developments in surgical treatment. The clinical manifestations of OCD are covered, as well as the differentiation between OCD and other neuropsychiatric disorders with similar presentations. Chapters on spectrum illnesses including body dysmorphic disorder, impulse control disorders such as trichotillomania, and hoarding are also included. This book will appeal to all mental health professionals, from practitioners to researchers, working in the field of compulsive disorders.