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A modification of the quartimax computation for factor rotation is described in which a hypothesized factor pattern is given to the machine along with the data. The machine uses the pattern to select the subset of variables to which it will attend when rotating in a given plane, in order to find an orthogonal solution which closely fits the hypothesis. The program also provides a measure of the goodness of this fit. The program can utilize pattern matrices that reflect only partial hypotheses as to the nature of the factors, as well as those that specify highly determined simple structure.
Ignorance concerning the standard error of individual factor loadings and their differences has been a major obstacle to the proper interpretation of factorial results. The effects of three types of experimental error (selection of variables, selection of subjects and selection of scores) are here reported. In order to handle the errors of rotation systematically, it has been necessary to introduce a new semi-analytical criterion for the attainment of simple structure. Variability in results which may theoretically be eliminated is discussed under the heading of non-essential error.
Factorial transformation is viewed as an estimation problem in which the usual assumption of homogeneously distributed error cannot be applied, but may be replaced by a principle of maximum kurtosis. This leads to quartimax in the orthogonal case, and to “oblimax” in the oblique case. Oblimax is readily programmable, and typically provides results similar to those of subjective rotation. However, oblimax may encounter special difficulty in data which do not determine a simple structure, or which have been imprecisely factored.
This study compares a quartimax rotation of the centroid factor loadings for Thurstone's Primary Mental Abilities Test Battery with factorings of the same correlation matrix by Thurstone (simple structure), Zimmerman (revised simple structure), Holzinger and Harman (bi-factor analysis), and Eysenck (group factor analysis). The quartimax results agree very closely with the solutions of Holzinger and Harman and of Eysenck, and reasonably well with the two simple structure analyses. The principal difference is the general factor provided by the quartimax solution. Reproduction of the factorial structure is sufficiently good to justify its use at least as the first stage of rotation. More extensive trial of the method will be needed with more varied data before it will be possible to decide whether quartimax factors meet psychological requirements sufficiently well without further rotation.
This paper reports on the third of a series of four experiments using similar concepts and methods for objective personality measurement, and overlapping test batteries. One hundred students were measured with 115 tests. The scores were correlated and factored by a re-iterated multiple group centroid method. The 17 factors thus obtained were rotated toward a clear simple structure. The relation of the rotated factors to earlier ones is indicated, but no extensive interpretation is attempted.
Attendance at university can result in social support network disruption. This can have a negative impact on the mental health of young people. Demand for mental health support continues to increase in universities, making identification of factors associated with poorer outcomes a priority. Although social functioning has a bi-directional relationship with mental health, its association with effectiveness of psychological treatments has yet to be explored.
Objectives
To explore whether students showing different trajectories of change in social function over the course of treatment differed in eventual treatment outcome.
Methods
Growth mixture models were estimated on a sample of 5221 students treated in routine mental health services. Different trajectories of change in self-rated impairment in social leisure activities and close relationships (Work and Social Adjustment Scale (WSAS) items 3 and 5) during the course of treatment were identified. Associations between trajectory classes and treatment outcomes were explored through multinomial regression.
Results
Five trajectory classes were identified for social leisure activity impairment (Figure 1), and three classes were identified for close relationship impairment (Figure 2). For both measures the majority of students remained mildly impaired (Class 1). Other trajectories included severe impairment with limited improvement (Class 2), severe impairment with delayed improvement (Class 3), and, in social leisure activities only, rapid improvement (Class 4), and deterioration (Class 5). There was an association between trajectories of improvement in social functioning over time and positive treatment outcomes. Trajectories of worsening or stable severe impairment were associated with negative treatment outcomes.
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Conclusions
Changes in social functioning impairment are associated with psychological treatment outcomes in students, suggesting that these changes may be associated with treatment effectiveness or recovery experiences. Future research should look to establish whether a causal link exists to understand if additional benefit for students can be gained through integrating social support within psychological treatment.
Autistic people have a high likelihood of developing mental health difficulties but a low chance of receiving effective mental healthcare. Therefore, there is a need to identify and examine strategies to improve mental healthcare for autistic people.
Aims
To identify strategies that have been implemented to improve access, experiences of care and mental health outcomes for autistic adults, and to examine evidence on their acceptability, feasibility and effectiveness.
Method
A co-produced systematic review was conducted. MEDLINE, PsycINFO, CINHAL, medRxiv and PsyArXiv were searched. We included all study designs reporting acceptability or feasibility outcomes and empirical quantitative study designs reporting effectiveness outcomes. Data were synthesised using a narrative approach.
Results
A total of 30 articles were identified. These included 16 studies of adapted mental health interventions, eight studies of service improvements and six studies of bespoke mental health interventions developed for autistic people. There was no conclusive evidence on effectiveness. However, most bespoke and adapted approaches appeared to be feasible and acceptable. Identified adaptations appeared to be acceptable and feasible, including increasing knowledge and detection of autism, providing environmental adjustments and communication accommodations, accommodating individual differences and modifying the structure and content of interventions.
Conclusion
Many identified strategies are feasible and acceptable, and can be readily implemented in services with the potential to make mental healthcare more suitable for autistic people, but important research gaps remain. Future research should address these and investigate a co-produced package of service improvement measures.
Autistic children and young people (CYP) experience mental health difficulties but face many barriers to accessing and benefiting from mental health care. There is a need to explore strategies in mental health care for autistic CYP to guide clinical practice and future research and support their mental health needs. Our aim was to identify strategies used to improve mental health care for autistic CYP and examine evidence on their acceptability, feasibility, and effectiveness. A systematic review and meta-analysis were carried out. All study designs reporting acceptability/feasibility outcomes and empirical quantitative studies reporting effectiveness outcomes for strategies tested within mental health care were eligible. We conducted a narrative synthesis and separate meta-analyses by informant (self, parent, and clinician). Fifty-seven papers were included, with most investigating cognitive behavioral therapy (CBT)-based interventions for anxiety and several exploring service-level strategies, such as autism screening tools, clinician training, and adaptations regarding organization of services. Most papers described caregiver involvement in therapy and reported adaptations to communication and intervention content; a few reported environmental adjustments. In the meta-analyses, parent- and clinician-reported outcomes, but not self-reported outcomes, showed with moderate certainty that CBT for anxiety was an effective treatment compared to any comparison condition in reducing anxiety symptoms in autistic individuals. The certainty of evidence for effectiveness, synthesized narratively, ranged from low to moderate. Evidence for feasibility and acceptability tended to be positive. Many identified strategies are simple, reasonable adjustments that can be implemented in services to enhance mental health care for autistic individuals. Notable research gaps persist, however.
Cryosols from Maritime Antarctica have been less studied than soils from continental areas of Antarctica. In this work X-ray diffraction, difference X-ray diffraction, differential thermal analysis, thermogravimetry, transmission electron microscopy/energy dispersive spectroscopy and selective chemical dissolution were used to characterize the clay fraction of basaltic, acid sulfate and ornithogenic Cryosols from ice-free areas of Admiralty Bay, King George Island. Non-crystalline phases are important soil components and reach >75% of the clay fraction for some ornithogenic soils. Randomly interstratified smectite-hydroxy-Al-interlayered smectite is the main clay mineral of basaltic soils. Kaolinite, chlorite and regularly interstratified illite-smectite predominate in acid sulfate soils. Jarosite is also an important component of the clay fraction in these soils. Crystalline Al and Fe phosphates occur in the clay at sites directly affected by penguin activity and the chemical characteristics of these ornithogenic sites are controlled by highly reactive, non-crystalline Al, Si, Fe and P phases. Chemical weathering is an active process in Cryosols in Maritime Antarctica and is enhanced by the presence of sulfides for some parent materials, and faunal activity.
Preeclampsia (PE) affects up to five times more women with pre-existing diabetes mellitus (PDM) than women without it. The present study aimed to identify the effect of the DASH diet on PE incidence (primary outcome) and blood pressure, glycated haemoglobin (GH), serum lipids, glutathione peroxidase (GP), C-reactive protein (CRP – secondary outcomes) in pregnant with PDM. This randomised, controlled, single-blind trial studied sixty-eight pregnant women with PDM throughout prenatal care until delivery (18 weeks) at a public maternity hospital, Brazil. The standard diet group (SDG) received a diet containing 45–65 % carbohydrates, 15–20 % protein and 25–30 % lipids. The DASH diet group (DDG) received the adapted DASH diet with a similar macronutrient distribution, but with a higher concentration of fibres, unsaturated fats, calcium, magnesium and potassium as well as lower saturated fat. Student's t, Mann–Whitney U and the Chi-square tests were used to compare outcomes. PE incidence was 22⋅9 % in the SDG and 12⋅1 % in the DDG (P = 0⋅25). GP levels significantly increased in the DDG (intra-group analysis; mean difference = 1588 [CI 181, 2994], P = 0⋅03) and tended to be different from the variation in the SDG (mean difference = −29⋅5 [CI −1305; 1⋅365]; v. DDG: 1588 [CI 181; 2994], P = 0⋅09). GH levels decreased significantly and similarly between groups (SDG: −0⋅61 [CI −0⋅26, −0⋅96], P = 0⋅00) v. DDG: −1⋅1 [CI −0⋅57, −1⋅62], P = 0⋅00). There was no evidence of a difference in PE incidence at the end of the intervention between the two diets. The DASH diet seems to favour PE-related biochemical markers.
The causal impacts of recreational cannabis legalization are not well understood due to the number of potential confounds. We sought to quantify possible causal effects of recreational cannabis legalization on substance use, substance use disorder, and psychosocial functioning, and whether vulnerable individuals are more susceptible to the effects of cannabis legalization than others.
Methods
We used a longitudinal, co-twin control design in 4043 twins (N = 240 pairs discordant on residence), first assessed in adolescence and now age 24–49, currently residing in states with different cannabis policies (40% resided in a recreationally legal state). We tested the effect of legalization on outcomes of interest and whether legalization interacts with established vulnerability factors (age, sex, or externalizing psychopathology).
Results
In the co-twin control design accounting for earlier cannabis frequency and alcohol use disorder (AUD) symptoms respectively, the twin living in a recreational state used cannabis on average more often (βw = 0.11, p = 1.3 × 10−3), and had fewer AUD symptoms (βw = −0.11, p = 6.7 × 10−3) than their co-twin living in an non-recreational state. Cannabis legalization was associated with no other adverse outcome in the co-twin design, including cannabis use disorder. No risk factor significantly interacted with legalization status to predict any outcome.
Conclusions
Recreational legalization was associated with increased cannabis use and decreased AUD symptoms but was not associated with other maladaptations. These effects were maintained within twin pairs discordant for residence. Moreover, vulnerabilities to cannabis use were not exacerbated by the legal cannabis environment. Future research may investigate causal links between cannabis consumption and outcomes.
Stress during handling can negatively impact the welfare of an animal. Gradual habituation or systematic desensitisation can reduce this but is not always possible. Blindfolding has been shown to decrease stress indicators, including heart rate and struggling in cattle (Bos taurus), but has not been studied in domestic rabbits (Oryctolagus cuniculus). We surveyed 49 wildlife rescues, rehabilitators and veterinarians, and found that blindfolding and swaddling are widely used and believed to reduce stress and struggling in rabbits. However, these methods may simply preclude escape and result in sensitisation over repeated exposure. We next conducted a controlled trial investigating the effects of blindfolding and swaddling repeatedly over five days on behavioural and physiological indicators of stress in 40 domestic rabbits. Neither blindfolding nor swaddling had significant impacts on heart or respiratory rate, compared to a partial hood control treatment, which involved similar levels of manipulation, but without visual or movement restriction. Behavioural responses showed variable trends, eg rabbits were more likely to approach food after handling with swaddling. Baseline levels varied significantly between individuals, suggesting previous experience to be an important determinant. Heart rates were universally high, showing that individuals in this study were stressed by handling to such an extent, that overall, effects of both blindfolding and swaddling on physiological indicators of stress were minimal. We suggest that blindfolding and swaddling may be useful as means of limiting the procedure duration and risk of injury by reducing struggling, but this study provides no evidence that welfare is otherwise improved.
There is substantial variation in patient symptoms following psychological therapy for depression and anxiety. However, reliance on endpoint outcomes ignores additional interindividual variation during therapy. Knowing a patient's likely symptom trajectories could guide clinical decisions. We aimed to identify latent classes of patients with similar symptom trajectories over the course of psychological therapy and explore associations between baseline variables and trajectory class.
Methods
Patients received high-intensity psychological treatment for common mental health problems at National Health Service Improving Access to Psychological Therapies services in South London (N = 16 258). To identify trajectories, we performed growth mixture modelling of depression and anxiety symptoms over 11 sessions. We then ran multinomial regressions to identify baseline variables associated with trajectory class membership.
Results
Trajectories of depression and anxiety symptoms were highly similar and best modelled by four classes. Three classes started with moderate-severe symptoms and showed (1) no change, (2) gradual improvement, and (3) fast improvement. A final class (4) showed initially mild symptoms and minimal improvement. Within the moderate-severe baseline symptom classes, patients in the two showing improvement as opposed to no change tended not to be prescribed psychotropic medication or report a disability and were in employment. Patients showing fast improvement additionally reported lower baseline functional impairment on average.
Conclusions
Multiple trajectory classes of depression and anxiety symptoms were associated with baseline characteristics. Identifying the most likely trajectory for a patient at the start of treatment could inform decisions about the suitability and continuation of therapy, ultimately improving patient outcomes.
This well-balanced introduction to enterprise risk management integrates quantitative and qualitative approaches and motivates key mathematical and statistical methods with abundant real-world cases - both successes and failures. Worked examples and end-of-chapter exercises support readers in consolidating what they learn. The mathematical level, which is suitable for graduate and senior undergraduate students in quantitative programs, is pitched to give readers a solid understanding of the concepts and principles involved, without diving too deeply into more complex theory. To reveal the connections between different topics, and their relevance to the real world, the presentation has a coherent narrative flow, from risk governance, through risk identification, risk modelling, and risk mitigation, capped off with holistic topics - regulation, behavioural biases, and crisis management - that influence the whole structure of ERM. The result is a text and reference that is ideal for graduate and senior undergraduate students, risk managers in industry, and anyone preparing for ERM actuarial exams.
In this chapter, we study risks associated with movements of interest rates in financial markets. We begin with a brief discussion of the term structure of interest rates. We then discuss commonly used interest rate sensitive securities. This is followed by the study of different measures of sensitivity to interest rates, including duration and convexity. We consider mitigating interest rate risk through hedging and immunization. Finally, we take a more in-depth look at the drivers of interest rate term structure dynamics.