Gravitational waves from coalescing neutron stars encode information about nuclear matter at extreme densities, inaccessible by laboratory experiments. The late inspiral is influenced by the presence of tides, which depend on the neutron star equation of state. Neutron star mergers are expected to often produce rapidly rotating remnant neutron stars that emit gravitational waves. These will provide clues to the extremely hot post-merger environment. This signature of nuclear matter in gravitational waves contains most information in the 2–4 kHz frequency band, which is outside of the most sensitive band of current detectors. We present the design concept and science case for a Neutron Star Extreme Matter Observatory (NEMO): a gravitational-wave interferometer optimised to study nuclear physics with merging neutron stars. The concept uses high-circulating laser power, quantum squeezing, and a detector topology specifically designed to achieve the high-frequency sensitivity necessary to probe nuclear matter using gravitational waves. Above 1 kHz, the proposed strain sensitivity is comparable to full third-generation detectors at a fraction of the cost. Such sensitivity changes expected event rates for detection of post-merger remnants from approximately one per few decades with two A+ detectors to a few per year and potentially allow for the first gravitational-wave observations of supernovae, isolated neutron stars, and other exotica.

We investigate experimentally the turbulent flow through a two-dimensional contraction. Using a water tunnel with an active grid we generate turbulence at Taylor microscale Reynolds number $Re_{\unicode[STIX]{x1D706}}\sim 250$ which is advected through a 2.5 : 1 contraction. Volumetric and time-resolved tomographic particle image velocimetry and shake-the-box velocity measurements are used to characterize the evolution of coherent vortical structures at three streamwise locations upstream of and within the contraction. We confirm the conceptual picture of coherent large-scale vortices being stretched and aligned with the mean rate of strain. This alignment of the vortices with the tunnel centreline is stronger compared to the alignment of vorticity with the large-scale strain observed in numerical simulations of homogeneous turbulence. We judge this by the peak probability magnitudes of these alignments. This result is robust and independent of the grid-rotation protocols. On the other hand, while the pointwise vorticity vector also, to a lesser extent, aligns with the mean strain, it principally remains aligned with the intermediate eigenvector of the local instantaneous strain-rate tensor, as is known in other turbulent flows. These results persist when the distance from the grid to the entrance of the contraction is doubled, showing that modest transverse inhomogeneities do not significantly affect these vortical-orientation results.

Early behaviors that differentiate later biomarkers for psychopathology can guide preventive efforts while also facilitating pathophysiological research. We tested whether error-related negativity (ERN) moderates the link between early behavior and later psychopathology in two early childhood phenotypes: behavioral inhibition and irritability. From ages 2 to 7 years, children (n = 291) were assessed longitudinally for behavioral inhibition (BI) and irritability. Behavioral inhibition was assessed via maternal report and behavioral responses to novelty. Childhood irritability was assessed using the Child Behavior Checklist. At age 12, an electroencephalogram (EEG) was recorded while children performed a flanker task to measure ERN, a neural indicator of error monitoring. Clinical assessments of anxiety and irritability were conducted using questionnaires (i.e., Screen for Child Anxiety Related Disorders and Affective Reactivity Index) and clinical interviews. Error monitoring interacted with early BI and early irritability to predict later psychopathology. Among children with high BI, an enhanced ERN predicted greater social anxiety at age 12. In contrast, children with high childhood irritability and blunted ERN predicted greater irritability at age 12. This converges with previous work and provides novel insight into the specificity of pathways associated with psychopathology.

The Numeniini is a tribe of 13 wader species (Scolopacidae, Charadriiformes) of which seven are Near Threatened or globally threatened, including two Critically Endangered. To help inform conservation management and policy responses, we present the results of an expert assessment of the threats that members of this taxonomic group face across migratory flyways. Most threats are increasing in intensity, particularly in non-breeding areas, where habitat loss resulting from residential and commercial development, aquaculture, mining, transport, disturbance, problematic invasive species, pollution and climate change were regarded as having the greatest detrimental impact. Fewer threats (mining, disturbance, problematic native species and climate change) were identified as widely affecting breeding areas. Numeniini populations face the greatest number of non-breeding threats in the East Asian-Australasian Flyway, especially those associated with coastal reclamation; related threats were also identified across the Central and Atlantic Americas, and East Atlantic flyways. Threats on the breeding grounds were greatest in Central and Atlantic Americas, East Atlantic and West Asian flyways. Three priority actions were associated with monitoring and research: to monitor breeding population trends (which for species breeding in remote areas may best be achieved through surveys at key non-breeding sites), to deploy tracking technologies to identify migratory connectivity, and to monitor land-cover change across breeding and non-breeding areas. Two priority actions were focused on conservation and policy responses: to identify and effectively protect key non-breeding sites across all flyways (particularly in the East Asian- Australasian Flyway), and to implement successful conservation interventions at a sufficient scale across human-dominated landscapes for species’ recovery to be achieved. If implemented urgently, these measures in combination have the potential to alter the current population declines of many Numeniini species and provide a template for the conservation of other groups of threatened species.

Volunteer horseradish plants that emerged from root segments remaining after harvest can reduce yields of rotational crops as well as provide a host for pathogens and insects, thus reducing the benefits of crop rotation. POST applications of halosulfuron in corn can be an effective component to improve management of volunteer horseradish, but the replant interval from application to safe planting of commercial horseradish has not been determined. Fall herbicide applications are another possible volunteer horseradish management strategy than can be implemented once crops are harvested. Therefore, field experiments were conducted to evaluate the safe replant interval of horseradish following halosulfuron applications and to determine the efficacy of fall herbicide applications for volunteer horseradish control. Visual estimates of horseradish injury were greatest (85%) in plantings made zero months after halosulfuron applied at two times the approved rate; moreover, for all rates, injury decreased as the time after halosulfuron application increased. No herbicide injury or root biomass reduction occurred on horseradish at any halosulfuron rate from replanting beyond 4 mo after halosulfuron application. Control of volunteer horseradish was 91% or greater for all fall herbicide applications that included 2,4-D. Furthermore, volunteer horseradish shoot density was the lowest following combinations of 2,4-D tank-mixed with halosulfuron or rimsulfuron : thifensulfuron (0.2 and 0.4 shoots m−2, respectively) compared with the nontreated control (5.1 shoots m−2). This research demonstrates the effectiveness of both halosulfuron and 2,4-D as components of an integrated management strategy for volunteer horseradish control and the potential for halosulfuron applications without soil persistence beyond 4 mo affecting subsequent commercial horseradish production.

Few records in the alpine landscape of western North America document the geomorphic and glaciologic response to climate change during the Pleistocene–Holocene transition. While moraines can provide snapshots of glacier extent, high-resolution records of environmental response to the end of the Last Glacial Maximum, Younger Dryas cooling, and subsequent warming into the stable Holocene are rare. We describe the transition from the late Pleistocene to the Holocene using a ~ 17,000-yr sediment record from Swiftcurrent Lake in eastern Glacier National Park, MT, with a focus on the period from ~ 17 to 11 ka. Total organic and inorganic carbon, grain size, and carbon/nitrogen data provide evidence for glacial retreat from the late Pleistocene into the Holocene, with the exception of a well-constrained advance during the Younger Dryas from 12.75 to 11.5 ka. Increased detrital carbonate concentration in Swiftcurrent Lake sediment reflects enhanced glacial erosion and sediment transport, likely a result of a more proximal ice terminus position and a reduction in the number of alpine lakes acting as sediment sinks in the valley.

Molecular imprinting is the process by which molecules are imprinted into the matrix of a material through non-covalent bonding, including hydrogen bonding and van der Waals interactions. In this study hydrogels were imprinted with glaucoma medication with the purpose of creating a reusable ocular drug delivery device with reversible binding sites. The material was synthesized and tested with UV-Vis spectroscopy to determine the concentration of the released drug after twelve hours in distilled water. Modifications were made to the polymer to explore methods required for the proper delivery of the drug over an adequate period of time.

Behavioral inhibition, a temperament identifiable in infancy, is associated with heightened withdrawal from social encounters. Prior studies raise particular interest in the striatum, which responds uniquely to monetary gains in behaviorally inhibited children followed into adolescence. Although behavioral manifestations of inhibition are expressed primarily in the social domain, it remains unclear whether observed striatal alterations to monetary incentives also extend to social contexts. In the current study, imaging data were acquired from 39 participants (17 males, 22 females; ages 16–18 years) characterized since infancy on measures of behavioral inhibition. A social evaluation task was used to assess neural response to anticipation and receipt of positive and negative feedback from novel peers, classified by participants as being of high or low interest. As with monetary rewards, striatal response patterns differed during both anticipation and receipt of social reward between behaviorally inhibited and noninhibited adolescents. The current results, when combined with prior findings, suggest that early-life temperament predicts altered striatal response in both social and nonsocial contexts and provide support for continuity between temperament measured in early childhood and neural response to social signals measured in late adolescence and early adulthood.