Fatigue properties of a wrought Ni-base superalloy treated by laserglazing and post heat treatments have been investigated. Tests have been run both by the rotating bend fatigue at 700°C and the vibration fatigue of turbine blades at room temperature. The results showed that the fatigue property of laserglazed specimens was obviously deteriorated because of resolution of γ′ phase and grain boundary carbide, interdendritic segregation of TiC and microcrack caused by thermal stress. However, suitable preheating and post heat treatment added before and after laserglazing can eliminate these defects and recover the fatigue life of this superalloy. Selected laser processing technology was applied to repairing blades rejected due to microcracks at trailing edge. The vibration fatigue life of blades repaired by laserglazing and post heat treatment was over two times as high as that of normal used blades with same service time.