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20 results

  • The Birmingham Registry for Twin and Heritability Studies (BiRTHS)

  • Ruth E. Krone, Andrew K. Ewer, Timothy G. Barrett, Robert J. Moy, Shagaf Bakour, Eamonn R. Maher, Shakila Thangaratinam, Philip Cox, Bill Martin, Khalid S. Khan, Maurice P. Zeegers
  • Journal:
    Twin Research and Human Genetics / Volume 9 / Issue 6 / 01 December 2006
    Published online by Cambridge University Press:
    21 February 2012, pp. 907-912
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  • In this article we present the protocol of the Birmingham Registry for Twin Heritability Studies (BiRTHS), which aims to establish a long-term prospective twin registry with twins identified from the antenatal period and subjected to detailed follow-up. We plan to investigate the concordance in anthropo-metrics and early childhood phenotypes between 66 monozygotic and 154 dizygotic twin pairs in the first 2 years of recruitment. In this project we plan to determine the relative contributions of heritability and environment to fetal growth, birth size, growth in infancy and development up to 2 years of age in an ethnically mixed population. Twins will be assessed with the Griffitth's Mental Development Scales, which will enable us to obtain detailed information on development. As maternal depression may have an effect on the twins' neurodevelopment, the Edinburgh Postnatal Depression Scale will be used at various stages during pregnancy and after delivery to assess maternal depressive symptoms. The increasing prevalence of obesity in both adults and children has raised concerns about the effect of maternal obesity in pregnancy on fetal growth. The prospective study design gives us the opportunity to obtain data on maternal nutrition (reflected by body mass index) and ante- and postnatal growth and development of twins.

  • Calculus at A-level and its understanding

  • Philip Maher
  • Journal:
    The Mathematical Gazette / Volume 75 / Issue 471 / March 1991
    Published online by Cambridge University Press:
    22 September 2016, pp. 68-71
    Print publication:
    March 1991

  • It is my contention that in the teaching of calculus at A level we have, all too often, been producing an understanding of calculus—and, implicitly, a view of mathematics—that is distorted and unrealistic. I am glad of the chance to air these criticisms in this contribution to the debate about the future of sixth form mathematics. (In this article, “sixth form” is synonymous with A level, whether studied at school or college.) Nevertheless, as I maintain later, the changes now being wrought in sixth form mathematics generally may well prove beneficial.

  • The centroid of an arc of wire

  • Philip Maher
  • Journal:
    The Mathematical Gazette / Volume 73 / Issue 465 / October 1989
    Published online by Cambridge University Press:
    01 August 2016, p. 238
    Print publication:
    October 1989
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