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As we have noted before, the WG-IR was created following a Joint Commission Meeting at the IAU General Assembly in Baltimore in 1988, a meeting that provided both diagnosis and prescription for the perceived ailments of infrared photometry at the time. The results were summarized in Milone (1989). The challenges involve how to explain the failure to systematically achieve the milli-magnitude precision expected of infrared photometry and an apparent 3% limit on system transformability. The proposed solution was to re-define the broadband Johnson system, the passbands of which had proven so unsatisfactory that over time effectively different systems proliferated although bearing the same JHKLMNQ designations; the new system needed to be better positioned and centered in the atmospheric windows of the Earth's atmosphere, and the variable water vapour content of the atmosphere needed to be measured in real time to better correct for atmospheric extinction.
Questions remain about the long-term health impacts of the 1991 Gulf War on its veterans.
To measure psychological disorders in Australian Gulf War veterans and a military comparison group and to explore any association with exposure to Gulf War-related psychological stressors.
Prevalences of DSM–IV psychological disorders were measured using the Composite International Diagnostic Interview. Gulf War-related psychological stressors were measured using a service experience questionnaire.
A total of 31% of male Gulf War veterans and 21% of the comparison group met criteria for a DSM–IVdisorder first present in the post-Gulf War period. The veterans were at greater risk of developing post-Gulf War anxiety disorders including post-traumatic stress disorder, affective disorders and substance use disorders. The prevalence of such disorders remained elevated a decade after deployment. The findings can be explained partly as a ‘war-deployment effect‘. There was a strong dose–response relationship between psychological disorders and number of reported Gulf War-related psychological stressors.
Service in the 1991 Gulf War is associated with increased risk of psychological disorders and these are related to stressful experiences.
Because cells can recognize and attach to short synthetic peptides containing the tripeptide sequence, arg-gly-asp (RGD), we have designed peptides which will spontaneously bind and present an active RGD sequence on biomaterial surfaces. We have analyzed a number of synthetic peptides and fully characterized one which fulfills this functional criteria. This peptide has been named PepTite-2000™. When biomaterials are placed in aqueous buffers containing PepTite-2000, the peptide rapidly binds to the surface and provides a site for cell attachment. Cell attachment occurs to PepTite-2000 coated materials by an RGD dependent mechanism using the αvβ3 integrin. This coating protocol is widely applicable, and the peptide will coat and promote cell attachment to all the commonly used biomaterials we have tested including dacron, teflon, titanium and silicone. Analysis of the soft tissue response to dacron implants coated with PepTite-2000 demonstrates that the coating results in more rapid tissue ingrowth and less giant cell recruitment around the implanted materials. These data demonstrate that PepTite-2000 can be used to modify biomaterial surfaces and present a more “natural” site for cell interactions.
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