The article describes the Bureau of African Affairs Collection. First it introduces the history of the archive by examining the crucial events that influenced its state and accessibility. Then, it describes the contents of the collection, underlying its importance for the study of Kwame Nkrumah’s domestic and foreign policies and African nationalism at a continental level. The documents included in the Bureau of African Affairs Collection provide unique insights into both Nkrumah’s foreign and domestic policies. In particular, they include invaluable information on his Pan-African policy. Moreover, the documents shed new light on the presence of African liberation movements in Ghana in the period 1957 to 1966. Thus, this Collection can attract scholars interested in both Ghanaian history as well as the history of Pan-Africanism and African nationalism at a continental level.