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5 results

  • Cognitive effects of brief and ultrabrief pulse bitemporal electroconvulsive therapy: a randomised controlled proof-of-concept trial

  • Donel Martin, Natalie Katalinic, Dusan Hadzi-Pavlovic, Anna Ingram, Nicholas Ingram, Brett Simpson, Jenny McGoldrick, Nathan Dowling, Colleen Loo
  • Journal:
    Psychological Medicine / Volume 50 / Issue 7 / May 2020
    Published online by Cambridge University Press:
    02 May 2019, pp. 1121-1128
    Print publication:
    May 2020
  • Background

    Reduction of the pulse width has been reported to improve ECT outcomes with unilateral ECT (similar efficacy, fewer cognitive side effects), but has been minimally studied for bitemporal ECT. The only study comparing brief and ultrabrief pulse bitemporal ECT found reduced efficacy for bitemporal ultrabrief compared to bitemporal brief pulse stimulation. This randomised controlled trial (RCT) aimed to test if ultrabrief pulse bitemporal ECT results in fewer cognitive side effects than brief pulse bitemporal ECT, when given at doses adjusted with the aim of achieving comparable efficacy.

    Methods

    Thirty-six participants were randomly assigned to receive ultrabrief (at 3 times seizure threshold) or brief (at 1.5 times seizure threshold) pulse bitemporal ECT given 3 times a week in a double-blind, controlled proof-of-concept trial. Blinded raters assessed mood and cognitive functioning over the ECT course.

    Results

    Efficacy and cognitive outcomes did not differ significantly between the two treatment groups over the ECT course. The ultrabrief pulse group performed better on a test of visual memory assessed acutely after an ECT treatment.

    Conclusions

    This study suggests there may be a small cognitive advantage in giving bitemporal ECT with an ultrabrief pulse when dosage is increased to match the efficacy of brief pulse bitemporal ECT, but the study was underpowered to fully examine this issue.

    Clinical Trials Registration: www.clinicaltrials.gov, NCT00870805.

  • New Labour's Partnerships: Comparing Conceptual Models with Existing Forms

  • Martin Powell, Bernard Dowling
  • Journal:
    Social Policy and Society / Volume 5 / Issue 2 / April 2006
    Published online by Cambridge University Press:
    26 April 2006, pp. 305-314
    Print publication:
    April 2006

  • The establishment of partnerships has been a central feature of British social welfare policy since 1997 when the New Labour government came to power. Although the academic attention given to partnership working since then has grown considerably, there have been few attempts to link conceptual models of partnerships with existing forms. This paper addresses this gap and finds that, while there are links between actual and model partnerships, there is little evidence that actual partnerships have been designed or structured to meet their particular tasks.