The prevalence of many diseases in pigs displays seasonal distributions. Despite growing concerns about the impacts of climate change, we do not yet have a good understanding of the role that weather factors play in explaining such seasonal patterns. In this study, national and county-level aggregated abattoir inspection data were assessed for England and Wales during 2010–2015. Seasonally-adjusted relationships were characterised between weekly ambient maximum temperature and the prevalence of both respiratory conditions and tail biting detected at slaughter. The prevalence of respiratory conditions showed cyclical annual patterns with peaks in the summer months and troughs in the winter months each year. However, there were no obvious associations with either high or low temperatures. The prevalence of tail biting generally increased as temperatures decreased, but associations were not supported by statistical evidence: across all counties there was a relative risk of 1.028 (95% CI 0.776–1.363) for every 1 °C fall in temperature. Whilst the seasonal patterns observed in this study are similar to those reported in previous studies, the lack of statistical evidence for an explicit association with ambient temperature may possibly be explained by the lack of information on date of disease onset. There is also the possibility that other time-varying factors not investigated here may be driving some of the seasonal patterns.

Ross River virus (RRV) is a mosquito-borne virus endemic to Australia. The disease, marked by arthritis, myalgia and rash, has a complex epidemiology involving several mosquito species and wildlife reservoirs. Outbreak years coincide with climatic conditions conducive to mosquito population growth. We developed regression models for human RRV notifications in the Mildura Local Government Area, Victoria, Australia with the objective of increasing understanding of the relationships in this complex system, providing trigger points for intervention and developing a forecast model. Surveillance, climatic, environmental and entomological data for the period July 2000–June 2011 were used for model training then forecasts were validated for July 2011–June 2015. Rainfall and vapour pressure were the key factors for forecasting RRV notifications. Validation of models showed they predicted RRV counts with an accuracy of 81%. Two major RRV mosquito vectors (Culex annulirostris and Aedes camptorhynchus) were important in the final estimation model at proximal lags. The findings of this analysis advance understanding of the drivers of RRV in temperate climatic zones and the models will inform public health agencies of periods of increased risk.

The focal article by Bergman and Jean (2016) raises an important issue by documenting the underrepresentation of nonprofessional and nonmanagerial workers in industrial and organizational (I-O) research. They defined workers as, “people who were not executive, professional or managerial employees; who were low- to medium-skill; and/or who were wage earners rather than salaried” (p. 89). This definition encompasses a wide range of employee samples: from individuals working in blue-collar skilled trades like electricians and plumbers to police officers, soldiers, and call center representatives to low-skill jobs such as fast food, tollbooth operators, and migrant day workers. Because there is considerable variability in the pay, benefits, skill level, autonomy, job security, schedule flexibility, and working conditions that define these workers’ experiences, a more fine-grained examination of who these workers are is necessary to understand the scope of the problem and the specific subpopulations of workers represented (or not) in existing I-O research.

The 2012 West Nile virus (WNV) epidemic was the largest since 2003 and the North Texas region was the most heavily impacted. We conducted a serosurvey of blood donors from four counties in the Dallas–Fort Worth area to characterize the epidemic. Blood donor specimens collected in November 2012 were tested for WNV-specific antibodies. Donors positive for WNV-specific IgG, IgM, and neutralizing antibodies were considered to have been infected in 2012. This number was adjusted using a multi-step process that accounted for timing of IgM seroreversion determined from previous longitudinal studies of WNV-infected donors. Of 4971 donations screened, 139 (2·8%) were confirmed WNV IgG positive, and 69 (1·4%) had IgM indicating infection in 2012. After adjusting for timing of sampling and potential seroreversion, we estimated that 1·8% [95% confidence interval (CI) 1·5–2·2] of the adult population in the Dallas–Fort Worth area were infected during 2012. The resulting overall estimate for the ratio of infections to reported WNV neuroinvasive disease (WNND) cases was 238:1 (95% CI 192–290), with significantly increased risk of WNND in older age groups. These findings were very similar to previous estimates of infections per WNND case, indicating no change in virulence as WNV evolved into an endemic infection in the United States.

Open science is a new concept for the practice of experimental laboratory-based research, such as drug discovery. The authors have recently gained experience in how to run such projects and here describe some straightforward steps others may wish to take towards more openness in their own research programmes. Existing and inexpensive online tools can solve many challenges, while some psychological barriers to the free sharing of all data and ideas are more substantial.

We carried out an extensive photometric and spectroscopic investigation of the SPB binary, HD 25558 (see Fig. 1 for the time and geographic distribution of the observations). The ~2000 spectra obtained at 13 observatories during 5 observing seasons, the ground-based multi-colour light curves and the photometric data from the MOST satellite revealed that this object is a double-lined spectroscopic binary with a very long orbital period of about 9 years. We determined the physical parameters of the components, and have found that both lie within the SPB instability strip. Accordingly, both components show line-profile variations consistent with stellar pulsations. Altogether, 11 independent frequencies and one harmonic frequency were identified in the data. The observational data do not allow the inference of a reliable orbital solution, thus, disentangling cannot be performed on the spectra. Since the lines of the two components are never completely separated, the analysis is very complicated. Nevertheless, pixel-by-pixel variability analysis of the cross-correlated line profiles was successful, and we were able to attribute all the frequencies to the primary or secondary component. Spectroscopic and photometric mode-identification was also performed for several of these frequencies of both binary components. The spectroscopic mode-identification results suggest that the inclination and rotation of the two components are rather different. While the primary is a slow rotator with ~6 d rotation period, seen at ~60° inclination, the secondary rotates fast with ~1.2 d rotation period, and is seen at ~20° inclination. Our spectropolarimetric measurements revealed that the secondary component has a magnetic field with at least a few hundred Gauss strength, while no magnetic field was detected in the primary.

The detailed analysis and results of this study will be published elsewhere.

In this work, we investigate the approach of a descending vortex pair to a horizontal ground plane. As in previous studies, the primary vortices exhibit a ‘rebound’, due to the separation of secondary opposite-sign vortices underneath each primary vortex. On each side of the flow, the weaker secondary vortex can become three-dimensionally unstable, as it advects around the stronger primary vortex. It has been suggested in several recent numerical simulations that elliptic instability is the origin of such waviness in the secondary vortices. In the present research, we employ a technique whereby the primary vortices are visualized separately from the secondary vortices; in fact, we are able to mark the secondary vortex separation, often leaving the primary vortices invisible. We find that the vortices are bent as a whole in a Crow-type ‘displacement’ mode, and, by keeping the primary vortices invisible, we are able to see both sides of the flow simultaneously, showing that the instability perturbations on the secondary vortices are antisymmetric. Triggered by previous research on four-vortex aircraft wake flows, we analyse one half of the flow as an unequal-strength counter-rotating pair, noting that it is essential to take into account the angular velocity of the weak vortex around the stronger primary vortex in the analysis. In contrast with previous results for the vortex–ground interaction, we find that the measured secondary vortex wavelength corresponds well with the displacement bending mode, similar to the Crow-type instability. We have analysed the elliptic instability modes, by employing the approximate dispersion relation of Le Dizés & Laporte (J. Fluid Mech., vol. 471, 2002, p. 169) in our problem, finding that the experimental wavelength is distinctly longer than predicted for the higher-order elliptic modes. Finally, we observe that the secondary vortices deform into a distinct waviness along their lengths, and this places two rows of highly stretched vertical segments of the vortices in between the horizontal primary vortices. The two rows of alternating-sign vortices translate towards each other and ultimately merge into a single vortex row. A simple point vortex row model is able to predict trajectories of such vortex rows, and the net result of the model’s ‘orbital’ or ‘passing’ modes is to bring like-sign vortices, from each secondary vortex row, close to each other, such that merging may ensue in the experiments.

In this study, we investigate the dynamics of a freely rising and falling cylinder. This is, in essence, a vortex-induced vibration (VIV) system comprising both transverse (Y) and streamwise (X) degrees-of-freedom (d.o.f.), but with zero spring stiffness and zero damping. This problem represents a limiting case among studies in VIV, and is an extension of recent research of elastically mounted bodies having very low spring stiffness, as well as bodies with very low mass and damping. We find that if the mass ratio (where m* = cylinder mass/displaced fluid mass) is greater than a critical value, m*crit = 0.545, the body falls or rises with a rectilinear trajectory. As the mass ratio is reduced below m*crit = 0.545, the cylinder suddenly begins to vibrate vigorously and periodically, with a 2P mode of vortex formation, as reported in the preliminary study of Horowitz & Williamson (J. Fluids Struct. vol. 22, 2006, pp. 837–843). The similarity in critical mass between freely rising and elastically mounted bodies is unexpected, as it is known that the addition of streamwise vibration can markedly affect the response and vortex formation in elastically mounted systems, which would be expected to modify the critical mass. However, we show in this paper that the similarity in vortex formation mode (2P) between the freely rising body and the elastically mounted counterpart is consistent with a comparable phase of vortex dynamics, strength of vortices, amplitudes and frequencies of motion and effective added mass (CEA). All of these similarities result in comparable values of critical mass. The principal fact that the 2P mode is observed for the freely rising body is an interesting and consistent result; based on the previous VIV measurements, this is the only mode out of the known set {2S, 2P, 2T} to yield negative effective added mass (CEA < 0), which is a condition for vibration of a freely rising body. In this paper, we deduce that there exists only one possible two degree-of-freedom elastically mounted cylinder system, which can be used to predict the dynamics of freely rising bodies. Because of the symmetry of the vortex wake, this system is one for which the natural frequencies are fNX = 2fNY. Although this seems clear in retrospect, previous attempts to predict critical mass did not take this into account. Implementing such an elastic system, we are able to predict vibration amplitudes and critical mass (m*crit = 0.57) for a freely rising cylinder in reasonable agreement with direct measurements for such a rising body, and even to predict the Lissajous figures representing the streamwise–transverse vibrations for a rising body with very small mass ratios (down to m* = 0.06), unobtainable from our direct measurements.

In this paper, we study the effect of the Reynolds number (Re) on the dynamics and vortex formation modes of spheres rising or falling freely through a fluid (where Re = 100–15000). Since the oscillation of freely falling spheres was first reported by Newton (University of California Press, 3rd edn, 1726, translated in 1999), the fundamental question of whether a sphere will vibrate, as it rises or falls, has been the subject of a number of investigations, and it is clear that the mass ratio m* (defined as the relative density of the sphere compared to the fluid) is an important parameter to define when vibration occurs. Although all rising spheres (m* < 1) were previously found to oscillate, either chaotically or in a periodic zigzag motion or even to follow helical trajectories, there is no consensus regarding precise values of the mass ratio (m*crit) separating vibrating and rectilinear regimes. There is also a large scatter in measurements of sphere drag in both the vibrating and rectilinear regimes.

In our experiments, we employ spheres with 133 combinations of m* and Re, to provide a comprehensive study of the sphere dynamics and vortex wakes occurring over a wide range of Reynolds numbers. We find that falling spheres (m* > 1) always move without vibration. However, in contrast with previous studies, we discover that a whole regime of buoyant spheres rise through a fluid without vibration. It is only when one passes below a critical value of the mass ratio, that the sphere suddenly begins to vibrate periodically and vigorously in a zigzag trajectory within a vertical plane. The critical mass is nearly constant over two ranges of Reynolds number (m*crit ≈ 0.4 for Re = 260–1550 and m*crit ≈ 0.6 for Re > 1550). We do not observe helical or spiral trajectories, or indeed chaotic types of trajectory, unless the experiments are conducted in disturbed background fluid. The wakes for spheres moving rectilinearly are comparable with wakes of non-vibrating spheres. We find that these wakes comprise single-sided and double-sided periodic sequences of vortex rings, which we define as the ‘R’ and ‘2R’ modes. However, in the zigzag regime, we discover a new ‘4R’ mode, in which four vortex rings are created per cycle of oscillation. We find a number of changes to occur at a Reynolds number of 1550, and we suggest the possibility of a resonance between the shear layer instability and the vortex shedding (loop) instability. From this study, ensuring minimal background disturbances, we have been able to present a new regime map of dynamics and vortex wake modes as a function of the mass ratio and Reynolds number {m*, Re}, as well as a reasonable collapse of the drag measurements, as a function of Re, onto principally two curves, one for the vibrating regime and one for the rectilinear trajectories.

Echovirus type 11 (echo 11) has been isolated at the virus laboratory of Fairfield Hospital, Melbourne, Australia, in 20 of the 28 years since the laboratory was established. During this time two major epidemics have occurred; the first, in 1971–2 involved 90 patients with aseptic meningitis or respiratory illness. The second began in June 1979 and lasted for 11 months, during which echo 11 was isolated from 174 patients admitted to Fairfield Hospital, other Victorian and Tasmanian hospitals and a children's reception centre. The patients' illnesses included viral meningitis (66%), fever (10%), respiratory infections (7%) and gastroenteritis (2%). One baby died.

Echo 11 was recovered from nasopharyngeal swabs or aspirates, cerebrospinal fluid and faecal specimens and was isolated most frequently in the Borrie cell line. Isolates were readily identified by immune electron microscopy and/or neutralization tests.

An outbreak of legionellosis associated with a hotel in Sydney, Australia, and the subsequent epidemiological and environmental investigations are described. Four cases of Legionnaires' disease were notified to the Public Health Unit. A cross-sectional study of 184 people who attended a seminar at the hotel was carried out. Serological and questionnaire data were obtained for 152 (83%) of these. Twenty-eight (18%) respondents reported symptoms compatible with legionellosis. Thirty-three subjects (22%) had indirect fluorescent antibody (IFA) titres to Legionella pneumophila serogroup 1 (Lp-1) of 128 or higher. The only site which those with symptoms of legionellosis and IFA titre ≥128 were more likely to have visited than controls was the hotel car park (adjusted odds ratio [OR] 14·7, 95% confidence interval [CI]: 1·8–123·1). Those with symptoms compatible with legionellosis, but whose IFA titres were < 128 were also more likely to have visited the hotel car park (adjusted OR 4·4, 95% CI: 1·5–12·9). Seroprevalence of Lp-1 antibodies was higher in those who attended the seminar than in a population sample of similar age. Findings suggested that the 4 cases represented a small fraction of all those infected, and highlighted difficulties in defining illness caused by Lp-1 and in interpreting serology.

The Thomson scattering spectrum, for laser light scattered by a low density plasma, is determined by the Doppler shifts from the moving electrons. It is shown how the full three-dimensional distribution function may be constructed if spectra are observed in several directions. Calculations using a model loss-cone distribution show that four spectra are sufficient for a faithful reconstruction of f(v). Most of the complications that arise at relativistic electron velocities can be avoided by placing a diffraction grating in the scattered laser beam.

Obesity is considered a risk factor for laminitis, insulin resistance and other medical problems in horses. The objective of this study was to test the hypothesis that a feeding and exercise programme would induce weight loss and affect indices of health in overweight horses. Twenty-three overweight (BCS 6.5–9.0) QH and TB horses were assigned to three groups: calorie restriction (DIET), calorie restriction plus exercise (DIETX) and a control group at weight maintenance (CON). Measurements included body weight, body condition score, rump fat thickness, glucose, insulin, leptin, non-esterified fatty acids (NEFA) and triglycerides. Frequently sampled intravenous glucose tolerance tests measured insulin sensitivity (SI), glucose effectiveness and acute insulin response to glucose (AIRg). Disposition index (DI) was calculated. DIETX underwent a fitness test (graded exercise test) on a treadmill before and after the experimental period, and performed a standardized submaximal exercise regimen in an Equi-ciser™. Horses in the DIETX group lost more weight (P < 0.01) than DIET or CON. DIET also lost more weight versus CON (P < 0.05). All groups had decreases (P < 0.05) in BCS, with DIETX and DIET exhibiting the largest decreases. DIET and DIETX decreased (P < 0.05) in rump fat thickness. Cortisol decreased (P < 0.05) in DIET, and NEFA decreased in DIETX pre- versus post-weight loss. There were decreases (P < 0.05) in leptin and AIRg in DIET and DIETX pre- versus post-weight loss. DI was decreased (P < 0.05) in DIET and CON. SI was decreased (P < 0.05) only in CON. Calorie restriction and calorie restriction plus exercise programmes were successful in achieving weight loss in overweight horses. Indices of obesity, physiological stress and fat metabolism can be significantly altered with calorie control and exercise.

The authors have recently treated (2) the problem of finding subsets E of the real line , of type Fσ, such that E–E contains an interval and the k-fold vector sum (k)E is of measure zero. Positive results can be obtained, for all k, on the basis of a recent theorem of J. A. Haight (3), following earlier partial results (1), (4) for k ≦ 7; and indeed in these cases the problem has a solution with E a perfect set. An analogous problem, apparently in most respects subtler than the first, is the following. Do there exist finite regular Borel measures μ on such that is absolutely continuous (where is the adjoint of μ) and the kth convolution power μk is singular? Both problems are of interest in the general context of elucidating the properties of the measure algebra or, more generally, M(G) for locally compact abelian G. The second problem may be regarded as an attempt to provide (at least one aspect of) a multiplicity theory for the first.

Summary

Background and objective: Sub-Tenon's block is usually delivered by the infero-nasal (IN) approach, but occasionally this may not be possible. The infero-temporal (IT) approach has been described, but data is not available on its efficacy. Methods: One hundred patients undergoing cataract extraction were randomized to receive an IN or IT sub-Tenon's injection of lidocaine 2% with hyaluronidase 15 IU mL−1. Akinesia was assessed using the Brahma scale at 0, 2, 4, 6 and 8 min. Injection, intraoperative and postoperative pain scores (verbal analogue score, 0–10) were noted, along with the incidence of sub-conjunctival haemorrhage and chemosis. Results: There were no differences in patient characteristics data, or mean volume of administered local anaesthetic solution (3.3 (SD = 0.4) mL). There were no significant differences between groups in terms of onset of akinesia. Mean akinesia scores at 2, 4, 6 and 8 min were 2.7, 1.1, 0.4 and 0.2 for Group IN, compared to 2.2, 0.9, 0.8 and 0.3 for Group IT. Chemosis occurred in 14 patients in Group IN, compared to 22 in Group IT (P = 0.21).A sub-conjunctival haemorrhage was noted in 14 patients in Group IN and 19 patients in Group IT (P = 0.52). No patients required supplementary injections. Mean pain scores for the injection, intraoperatively and postoperatively were 0.9, 0 and 0 for Group IN, compared to 1.1, 0 and 0 for group IT. The surgeons scored all the blocks as ‘good’ except for one patient in each group. Conclusions: The IT approach provides an equally rapid onset of block, without a significant increase in complications.

An updated compilation of published and new data of major-ion (Ca, Cl, K, Mg, Na, NO3, SO4) and methylsulfonate (MS) concentrations in snow from 520 Antarctic sites is provided by the national ITASE (International Trans-Antarctic Scientific Expedition) programmes of Australia, Brazil, China, Germany, Italy, Japan, Korea, New Zealand, Norway, the United Kingdom, the United States and the national Antarctic programme of Finland. The comparison shows that snow chemistry concentrations vary by up to four orders of magnitude across Antarctica and exhibit distinct geographical patterns. The Antarctic-wide comparison of glaciochemical records provides a unique opportunity to improve our understanding of the fundamental factors that ultimately control the chemistry of snow or ice samples. This paper aims to initiate data compilation and administration in order to provide a framework for facilitation of Antarctic-wide snow chemistry discussions across all ITASE nations and other contributing groups. The data are made available through the ITASE web page (http://www2.umaine.edu/itase/content/syngroups/snowchem.html) and will be updated with new data as they are provided. In addition, recommendations for future research efforts are summarized.