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2 results

  • Supratentorial Ectopic Ependymoma

  • Olivier Vernet, Jean-Pierre Farmer, Kathleen Meagher-Villemure, José L. Montes
  • Journal: Canadian Journal of Neurological Sciences / Volume 22 / Issue 4 / November 1995
  • Published online by Cambridge University Press: 18 September 2015, pp. 316-319
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  • Background

    Ependymomas usually arise from the ventricular surface.

    Methods

    We report an 11-year-old female who presented with a supratentorial ectopic ependymoma.

    Results

    The patient presented with a two-month-history of progressive headache, nausea and vomiting. Examination revealed papilledema, horizontal nystagmus, diplopia on upward gaze, and right pronator drift. CT scan showed an enhancing left precentral subcortical lesion measuring 3 cm in diameter with associated edema and mass effect. Its medial border was located 3 cm from the ependymal surface of the ventricle. A firm tumour was dissected from the centrum semiovale white matter, and removed in toto as confirmed on MRI. Pathological examination revealed histological, immuno-histochemical and electron microscopic features consistent with an ependymoma. Spine MRI and bone marrow aspirate, as well as lumbar puncture of cytology failed to show any dissemination.

    Conclusion

    From the literature review, this represents an exceptional ependymoma located at the distance from the ventricular system or cisterns. Different pathogenic alternatives are discussed.

  • X-Linked Hydrocephalus

  • Ruben I. Kuzniecky, Gordon V. Watters, Lise Watters, Kathleen Meagher-Villemure
  • Journal: Canadian Journal of Neurological Sciences / Volume 13 / Issue 4 / November 1986
  • Published online by Cambridge University Press: 18 September 2015, pp. 344-346
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  • Two French-Canadian families with seven cases of hydrocephalus in two generations are presented. The pattern of inheritance is consistent with an X-linked recessive transmission. The clinical and pathologic characteristics of this entity are reviewed. The anomaly of adducted thumbs was present in one patient and its cause is considered. The hypothesis of primary hydrocephalus and secondary compression of the aqueduct as the mechanism for aqueductal stenosis is discussed.