We examined white matter volumes in four prefrontal subregions using
structural magnetic resonance imaging in 10 pathological liars, 14
antisocial controls, and 20 normal controls. Liars showed a relatively
widespread increase in white matter (23-36%) in orbitofrontal, middle and
inferior, but not superior, frontal gyri compared with antisocial and normal
controls. This white matter increase may predispose some individuals to
pathological lying.