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  • P.023 The Pain in Dystonia Scale (PIDS): development and validation
  • V Bruno, B Achen, F Morgante, R Erro, SH Fox, MJ Edwards, A Schrag, M Stamelou, S Appel-Cresswell, G Defazio, K Ray-Chaudhuri, S Pirio Richardson, HA Jinnah, D Martino
  • Journal: Canadian Journal of Neurological Sciences / Volume 50 / Issue s2 / June 2023
  • Published online by Cambridge University Press: 05 June 2023, pp. S63-S64
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    Background: Pain in a common symptom in adult-onset idiopathic dystonia (AOID). An appropriate tool to understand this symptom is needed to improve AOID patients’ care. We developed a rating instrument for pain in AOID and validated it in cervical dystonia (CD). Methods: Development and validation of the Pain in Dystonia Scale (PIDS) in three phases: 1. International experts and participants generated and evaluated the preliminary items for content validity; 2. The PIDS was drafted and revised, followed by cognitive interviews to ensure suitability for self-administration; and 3. the clinimetric properties of the final PIDS were assessed in 85 participants. Results: PIDS evaluates pain severity (by body part), functional impact and external modulating factors. It showed high test-retest reliability the total score (0.9, p<0.001), intraclass correlation coefficients higher than 0.7 for all items and high internal consistency (Cronbach’s alpha 0.9). Convergent validity analysis revealed a strong correlation between the PIDS severity score and the TWSTRS pain subscale (0.8, p<0.001), the brief pain inventory short form (0.7, p<0.001) and impact of pain on daily functioning (0.7, p<0.001). Conclusions: The PIDS is the first specific questionnaire developed to evaluate pain in patients with AOID with high-level clinimetric properties in people with CD.

  • Chapter 1 - Parkinson’s Disease: An Overview of the Non-Motor Symptomatology
  • Edited by Néstor Gálvez-Jiménez, Florida International University, Amos D Korczyn, Tel-Aviv University, Ramón Lugo-Sanchez
  • Book: Non-motor Parkinson's Disease
  • Published online: 05 March 2022
  • Print publication: 10 March 2022, pp 3-17
  • View extract

    Summary

    Non-motor symptoms (NMS) are a crucial component of Parkinson’s disease (PD) and the burden of the range of NMS that occurs in PD is one of the main determinants of quality of life [1]. In 1817, Dr. James Parkinson already described several NMS in his “shaking palsy,” the condition that would later be named after him, including pain, constipation, and sleep disturbances [2]. Nonetheless, after a long period of inertia, over the last 20 to 25 years, the interest in NMS has increased and evidence suggests that the overall burden of NMS dominates and can influence the risk of developing motor parkinsonism in the premotor stage of PD while being a driving factor for quality of life [3]. The identification of NMS in PD has been greatly aided by the development of specific tools, such as the NMS questionnaire (NMSQ) in 2006 [4] and the NMS Scale (NMSS) in 2007 [5].

Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders
  • Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders
  • Diagnosis and Management
  • Edited by Dag Aarsland, Jeffrey Cummings, Daniel Weintraub, K. Ray Chaudhuri
  • Published online: 05 August 2013
  • Print publication: 29 August 2013
  • View description
    Psychiatric and cognitive changes are common in patients with Parkinson's disease and have key clinical consequences but, despite this, these symptoms are often under-diagnosed and under-treated, leading to increased morbidity and costs. With chapters focused on the major neuropsychiatric features, Neuropsychiatric and Cognitive Changes in Parkinson's Disease and Related Movement Disorders rectifies this deficit. Written by experts in the field, with a consistent focus on relevant clinical knowledge, it provides a comprehensive overview including all the major behavioral changes associated with movement disorders. The book provides broad, in-depth, accurate and up-to-date scientific information as well as crucial understanding and practical tools to help patients. The book is essential reading for clinicians working in neurology, psychiatry and geriatric medicine.

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