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In 2017, the World Health Organization published new nomenclature for preimplantation genetic diagnosis (PGD). They renamed the procedure preimplantation genetic testing (PGT), with PGT-M for monogenic diseases and PGT-SR for structural rearrangements. Preimplantation genetic screening (PGS) was renamed PGT-A (aneuploidy). In this chapter, PGT-M and PGT-SR will be referred to as PGT.
This fully updated new edition of a successful and popular practical guide is an indispensable account of modern in-vitro fertilization practice. Initial chapters cover theoretical aspects of gametogenesis and embryo development at the cellular and molecular level, while the latter half of the book describes the requisites for a successful IVF laboratory and the basic technologies in ART. Advanced techniques, including pre-implantation genetic diagnosis, vitrification and stem-cell technology, are comprehensively covered, providing up-to-date analyses of these groundbreaking technologies. This edition includes:New practical techniques, including preservation of fertility for cancer patients, stem-cell biology/technology, vitrification and in-vitro maturationA 'refresher' study review of fundamental principles of cell and molecular biologyThe latest information available from animal and human research in reproductive biologyPacked with a wealth of practical and scientific detail, this is a must for all IVF practitioners.