This paper presents a compilation of atmospheric radiocarbon for the period 1950–2019, derived from atmospheric CO2 sampling and tree rings from clean-air sites. Following the approach taken by Hua et al. (2013), our revised and extended compilation consists of zonal, hemispheric and global radiocarbon (14C) data sets, with monthly data sets for 5 zones (Northern Hemisphere zones 1, 2, and 3, and Southern Hemisphere zones 3 and 1–2). Our new compilation includes smooth curves for zonal data sets that are more suitable for dating applications than the previous approach based on simple averaging. Our new radiocarbon dataset is intended to help facilitate the use of atmospheric bomb 14C in carbon cycle studies and to accommodate increasing demand for accurate dating of recent (post-1950) terrestrial samples.

While the North American archaeological record signals the presence of early humans along the northeastern Pacific coast by the Late Pleistocene, we know little about the technological systems employed by these coastally oriented colonizing groups. We here report the discovery of the earliest unequivocal evidence for the use and manufacture of shell fishhooks in the western hemisphere. Four single-piece shell fishhooks dating to the terminal Pleistocene/early Holocene transition (between ~11,300 and 10,700 cal B.P.) have been excavated on Isla Cedros, Baja California, Mexico. One hook is directly dated at 9495 ± 25 B.P. with a marine reservoir–corrected age of 11,165–9185 cal B.P. Radiocarbon ages associated with three other shell fishhooks range between 8900 ± 25 B.P. and 10,415 ± 25 B.P, while median ages for the earliest contexts confirm occupation of the island by at least 12,600–12,000 cal B.P. The stratigraphic levels from which the fishhooks were recovered contained a diverse assemblage of fish remains, including deepwater species, indicative of boat use. Thus, some of the earliest known inhabitants of the Pacific coast of the Americas employed shell hook and line technology for offshore marine fishing at least by the Pleistocene-Holocene transition, if not earlier.

Combining atmospheric Δ14CO2 data sets from different networks or laboratories requires secure knowledge on their compatibility. In the present study, we compare Δ14CO2 results from the Heidelberg low-level counting (LLC) laboratory to 12 international accelerator mass spectrometry (AMS) laboratories using distributed aliquots of five pure CO2 samples. The averaged result of the LLC laboratory has a measurement bias of –0.3±0.5‰ with respect to the consensus value of the AMS laboratories for the investigated atmospheric Δ14C range of 9.6 to 40.4‰. Thus, the LLC measurements on average are not significantly different from the AMS laboratories, and the most likely measurement bias is smaller than the World Meteorological Organization (WMO) interlaboratory compatibility goal for Δ14CO2 of 0.5‰. The number of intercomparison samples was, however, too small to determine whether the measurement biases of the individual AMS laboratories fulfilled the WMO goal.

There is much current interest in excitatory amino acids and their receptors because of their postulated involvement in several disorders of the nervous system. They function as neurotransmitters, but can act as neurotoxins in some situations. They have been implicated in the pathogenesis of cerebral hypoxic/ischemic and hypoglycemic damage, in epilepsy, in some degenerative diseases, and in some forms of neurotoxin-induced cerebral dysfunction. These diseases may reflect abnormality in a system which has evolved to provide synaptic plasticity essential for learning and memory. The purpose of this paper is to explore the ramifications of such a hypothesis.

Amyotrophic lateral sclerosis (ALS) is proving intractable. Difficulties in pre-clinical studies contribute in small measure to this futility, but the chief reason for failure is an inadequate understanding of disease pathogenesis. Many acquired and inherited processes have been advanced as potential causes of ALS but, while they may predispose to disease, it seems increasingly likely that none leads directly to ALS. Rather, two recent overlapping considerations, both involving aberrant protein homeostasis, may provide a better explanation for a common disease phenotype and a common terminal pathogenesis. If so, therapeutic approaches will need to be altered and carefully nuanced, since protein homeostasis is essential and highly conserved. Nonetheless, these considerations provide new optimism in a difficult disease which has hitherto defied treatment.

The radiocarbon content of whole air provides a theoretically ideal and now observationally proven tracer for recently added fossil-fuel-derived CO2 in the atmosphere (Cff). Over large industrialized land areas, determination of Cff also constrains the change in CO2 due to uptake and release by the terrestrial biosphere. Here, we review the development of a Δ14CO2 measurement program and its implementation within the US portion of the NOAA Global Monitoring Division's air sampling network. The Δ14CO2 measurement repeatability is evaluated based on surveillance cylinders of whole air and equates to a Cff detection limit of <0.9 ppm from measurement uncertainties alone. We also attempt to quantify additional sources of uncertainty arising from non-fossil terms in the atmospheric 14CO2 budget and from uncertainties in the composition of “background” air against which Cff enhancements occur. As an example of how we apply the measurements, we present estimates of the boundary layer enhancements of Cff and Cbio using observations obtained from vertical airborne sampling profiles off of the northeastern US. We also present an updated time series of measurements from NOAA GMD's Niwot Ridge site at 3475 m asl in Colorado in order to characterize recent Δ14CO2 variability in the well-mixed free troposphere.

A workshop on atmospheric radiocarbon measurements was held in conjunction with the 21st International Radiocarbon conference in July 2012. The main topics were intercomparison of measurements of 14C in atmospheric CO2, the potential for use of gas standards for atmospheric 14C measurements, reporting of uncertainties, and expansion of intercomparison activities to other atmospheric trace gases. This report documents the discussions and conclusions of this workshop.

This article presents results from the first 3 rounds of an international intercomparison of measurements of Δ14CO2 in liter-scale samples of whole air by groups using accelerator mass spectrometry (AMS). The ultimate goal of the intercomparison is to allow the merging of Δ14CO2 data from different groups, with the confidence that differences in the data are geophysical gradients and not artifacts of calibration. Eight groups have participated in at least 1 round of the intercomparison, which has so far included 3 rounds of air distribution between 2007 and 2010. The comparison is intended to be ongoing, so that: a) the community obtains a regular assessment of differences between laboratories; and b) individual laboratories can begin to assess the long-term repeatability of their measurements of the same source air. Air used in the intercomparison was compressed into 2 high-pressure cylinders in 2005 and 2006 at Niwot Ridge, Colorado (USA), with one of the tanks “spiked” with fossil CO2, so that the 2 tanks span the range of Δ14CO2 typically encountered when measuring air from both remote background locations and polluted urban ones. Three groups show interlaboratory comparability within l% for ambient level Δ14CO2. For high CO2/low Δ14CO2 air, 4 laboratories showed comparability within 2%. This approaches the goals set out by the World Meteorological Organization (WMO) CO2 Measurements Experts Group in 2005. One important observation is that single-sample precisions typically reported by the AMS community cannot always explain the observed differences within and between laboratories. This emphasizes the need to use long-term repeatability as a metric for measurement precision, especially in the context of long-term atmospheric monitoring.

Polydipsia is a disorder that has received little attention in the research literature. Treatment has been mainly confined to medical or pharmacological intervention. Few studies have reported the use of contingency management techniques and none have sought to encourage self-management. This study shows how such a procedure brought about a significant change in rates of water drinking in a thirty-one year old man with a mild learning disability.

The diffusivity of implanted As in crystalline Si has been measured using Rutherford backscattering and channeling for specimens annealed at temperatures between 850 and 1000°C under pressures up to 30 kilobars. The diffusivity, at a given temperature, was found to increase with pressure with a maximum increase of a factor of ten. This diffusivity enhancement can be described by an average activation volume of -5.7±.8 cm3/mole. The activation enthalpy ranges from an ambient value of 4.5 eV to 3.6 eV at 30 kilobars

Having been a member of the Actuarial Society of Edinburgh for something like a quarter of a century, and having been during that period anything but a working bee, in so far as the interests of the Society are concerned, I felt, when I was asked to be its Honorary President for this session, that I had no claim whatever to the honour proposed to be conferred upon me.

Further reflection, however, led me to see that wrong-doing in the past formed no valid reason for a continuance of the same line of conduct in the future, but rather that the reverse should be the case. It seemed to me that, having hitherto failed to take my fair share of the work of the Society, I should best expiate my guilt by trying to do better in the future.

In coming to this conclusion, I was quite aware that the first mark of penitence I would be called upon to show would be the delivery of an Inaugural Address at the opening of this session, and that meant time for preparation, which, in a busy life otherwise, was not so easily secured. However, the time between the election of the Honorary President and the opening of the session was considerable, and I trusted to opportunity presenting itself.