Crime groups are drawn to stealing heritage and cultural property because the thefts can be less dangerous than other illicit activities and there can be a lower chance of detection. In addition, there are financial opportunities such as selling the objects, using them as currency and collateral in illicit markets, and through rewards and ransoms. While these factors remain, crime groups operating as criminal entrepreneurs will continue to be attracted to this type of theft even if situational crime prevention strategies are implemented at locations. Unique and irreplaceable heritage and cultural property will be stolen, and societies will lose in artistic, cultural, heritage, historical, and financial terms. This article argues that, while people tasked with the policing and security of heritage and cultural property should focus on the potential thefts, policing agencies also need to focus on the crime groups, especially as heritage and cultural property thefts can be crime groups’ “Achilles’ heel.”

We present the third data release from the Parkes Pulsar Timing Array (PPTA) project. The release contains observations of 32 pulsars obtained using the 64-m Parkes ‘Murriyang’ radio telescope. The data span is up to 18 yr with a typical cadence of 3 weeks. This data release is formed by combining an updated version of our second data release with $\sim$3 yr of more recent data primarily obtained using an ultra-wide-bandwidth receiver system that operates between 704 and 4032 MHz. We provide calibrated pulse profiles, flux density dynamic spectra, pulse times of arrival, and initial pulsar timing models. We describe methods for processing such wide-bandwidth observations and compare this data release with our previous release.

The novel coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), is the causative agent of the 2020 worldwide coronavirus pandemic. Antibody testing is useful for diagnosing historic infections of a disease in a population. These tests are also a helpful epidemiological tool for predicting how the virus spreads in a community, relating antibody levels to immunity and for assessing herd immunity. In the present study, SARS-CoV-2 viral proteins were recombinantly produced and used to analyse serum from individuals previously exposed, or not, to SARS-CoV-2. The nucleocapsid (Npro) and spike subunit 2 (S2Frag) proteins were identified as highly immunogenic, although responses to the former were generally greater. These two proteins were used to develop two quantitative enzyme-linked immunosorbent assays (ELISAs) that when used in combination resulted in a highly reliable diagnostic test. Npro and S2Frag-ELISAs could detect at least 10% more true positive coronavirus disease-2019 (COVID-19) cases than the commercially available ARCHITECT test (Abbott). Moreover, our quantitative ELISAs also show that specific antibodies to SARS-CoV-2 proteins tend to wane rapidly even in patients who had developed severe disease. As antibody tests complement COVID-19 diagnosis and determine population-level surveillance during this pandemic, the alternative diagnostic we present in this study could play a role in controlling the spread of the virus.

OBJECTIVES/GOALS: The goals of this evaluation were 1) to describe the pilot grant application cycle and processes at NC TraCS, 2) to illustrate the impact of pilot grants on extramural grant funding, and 3) to provide a framework for other institutions to utilize for the evaluation of pilot grant programs. METHODS/STUDY POPULATION: From 2009-2019 the NC TraCS pilot program funded 925 projects, varying from $2,000 to $100,000. Pilot grants are available to any researcher affiliated with the university as well as partner institutions and community stakeholders. For this evaluation we analyzed data on pilot applicants (demographics, type of pilot, funding status, resubmissions, etc.) and outcomes (extramural funding, publications, etc.) yielded from funded pilots. In addition to summary statistics, we also calculated return on investment (ROI) for the program as a whole and by specific grant type. We will use bibliometric network analysis to assess productivity, citation impact, and scope of collaboration. RESULTS/ANTICIPATED RESULTS: There have been 2,777 submitted proposals with an acceptance rate of 33.3%. Unfunded proposals can resubmit, 61.8% of resubmitted applications are successfully funded, and 29.6% of funded applications are resubmissions. The $2,000 awards accounted for 43.4% of all grants awarded but only accounted for 6.4% of all pilot funds awarded. Success of proposals was proportional to the number of applications from each academic unit. 60.8% of funded applicants were affiliated with the School of Medicine and account for 65.3% of all funding awarded from 2009-2019. Additionally, we plan on analyzing return on investment rates to illustrate the impact of pilot awards on future research funding. DISCUSSION/SIGNIFICANCE OF IMPACT: Pilot grants can lead to subsequent extramural grants, publications, and successful translation of research into practice. This evaluation will assist our institution in understanding the impact of pilot grants and will provide a road map for other institutions evaluating their own programs.

We describe 14 yr of public data from the Parkes Pulsar Timing Array (PPTA), an ongoing project that is producing precise measurements of pulse times of arrival from 26 millisecond pulsars using the 64-m Parkes radio telescope with a cadence of approximately 3 weeks in three observing bands. A comprehensive description of the pulsar observing systems employed at the telescope since 2004 is provided, including the calibration methodology and an analysis of the stability of system components. We attempt to provide full accounting of the reduction from the raw measured Stokes parameters to pulse times of arrival to aid third parties in reproducing our results. This conversion is encapsulated in a processing pipeline designed to track provenance. Our data products include pulse times of arrival for each of the pulsars along with an initial set of pulsar parameters and noise models. The calibrated pulse profiles and timing template profiles are also available. These data represent almost 21 000 h of recorded data spanning over 14 yr. After accounting for processes that induce time-correlated noise, 22 of the pulsars have weighted root-mean-square timing residuals of $<\!\!1\,\mu\text{s}$ in at least one radio band. The data should allow end users to quickly undertake their own gravitational wave analyses, for example, without having to understand the intricacies of pulsar polarisation calibration or attain a mastery of radio frequency interference mitigation as is required when analysing raw data files.

The Atypical Maternal Behavior Instrument for Assessment and Classification (AMBIANCE; Bronfman, Madigan, & Lyons-Ruth, 2009–2014; Bronfman, Parsons, & Lyons-Ruth, 1992–2004) is a widely used and well-validated measure for assessing disrupted forms of caregiver responsiveness within parent–child interactions. However, it requires evaluating approximately 150 behavioral items from videotape and extensive training to code, thus making its use impractical in most clinical contexts. Accordingly, the primary aim of the current study was to identify a reduced set of behavioral indicators most central to the AMBIANCE coding system using latent-trait item response theory (IRT) models. Observed mother–infant interaction data previously coded with the AMBIANCE was pooled from laboratories in both North America and Europe (N = 343). Using 2-parameter logistic IRT models, a reduced set of 45 AMBIANCE items was identified. Preliminary convergent and discriminant validity was evaluated in relation to classifications of maternal disrupted communication assigned using the full set of AMBIANCE indicators, to infant attachment disorganization, and to maternal sensitivity. The results supported the construct validity of the refined item set, opening the way for development of a brief screening measure for disrupted maternal communication. IRT models in clinical scale refinement and their potential for bridging clinical and research objectives in developmental psychopathology are discussed.

Management systems for direct-seeded and transplanted sugarbeets (Beta vulgaris L. ‘Mono Hy D2′) were compared for weed control and sugarbeet selectivity from 1983 through 1985 in western Nebraska. Broadleaf weed density was similar, but yellow foxtail [Setaria glauca (L.) Beauv. # SETLU] density was lower in transplanted compared to direct-seeded sugarbeets. Preplant soil-incorporated applications of cycloate (S-ethyl cyclohexylethylcarbamothioate) plus trifluralin [2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine] at 3.3 plus 0.6 kg ai/ha or ethofumesate [(±)-2-ethoxy-2,3-dihydro-3,3-dimethyl-5-benzofuranyl methanesulfonate] plus trifluralin at 2.2 plus 0.6 kg/ha was noninjurious to transplanted sugarbeets but caused severe injury to direct-seeded sugarbeets. The combination of cycloate or ethofumesate with trifluralin improved weed control over that obtained when cycloate or ethofumesate was used alone. By combining the improved weed control obtained from cycloate plus trifluralin or ethofumesate plus trifluralin with the transplanting crop establishment technique, a superior sugarbeet weed control program was developed.

Cores dating back to deglaciation were taken from three lakes in Atlantic Canada and analyzed for arcellaceans and pollen. Paleotemperatures and paleo-precipitation were calculated from the pollen data using transfer functions. A sudden warming is recorded by the pollen around 10,000 years B.P., followed by a general warming to the mid Holocene Hypsithermal, then by a decrease in temperature and increase in effective precipitation to the present. The three lakes, two in western Newfoundland and one in eastern Nova Scotia, contain similar late glacial (13-10 ka), early Holocene (10-8 ka), mid Holocene (8-4 ka), and late Holocene (4-0 ka) arcellacean assemblages. Immediately following retreat of the ice sheets, Centropyxis aculeata, Centropyxis constricta, Difflugia oblonga, Difflugia urceolata, and Difflugia corona were common. The latter part of the late glacial is characterized by sparse assemblages dominated by C. aculeata. The arcellacean record thus suggests a climatic reversal in Atlantic Canada between 11,500 and 10,000 years B.P., analogous to the Younger Dryas, although this is not recorded by the pollen. Species diversity increased sharply at the beginning of the Holocene, and D. oblonga is the dominant taxon in early Holocene sediments. Difflugia oblonga remained common through the mid Holocene, but percentages of C. aculeata were very low, and Pontigulasia compressa and Difflugia bacillifera peaked in abundance during the Hypsithermal. The late Holocene is characterized by a resurgence in C. aculeata at the expense of other taxa. The increase in Heleopera sphagni and Nebella collaris since 5,000 years B.P. at the two sites in southwestern Newfoundland reflects paludification in response to increased precipitation since the Hypsithermal. Because the changes in arcellacean assemblages are regionally synchronous in all three lakes and coincide with climatically driven vegetational successions indicated by the pollen record, arcellaceans appear to respond to climatic change, and thus may be useful paleoecological and paleolimnological indicators. With their quicker generation time, these protists may be better suited than pollen to recording short-lived phenomena, like the mid-Holocene Hypsithermal and the Younger Dryas reversal.

The issue of intermittency in numerical solutions of the 3D Navier–Stokes equations on a periodic box ${[0, L] }^{3} $ is addressed through four sets of numerical simulations that calculate a new set of variables defined by ${D}_{m} (t)= {({ \varpi }_{0}^{- 1} {\Omega }_{m} )}^{{\alpha }_{m} } $ for $1\leq m\leq \infty $ where ${\alpha }_{m} = 2m/ (4m- 3)$ and ${[{\Omega }_{m} (t)] }^{2m} = {L}^{- 3} \int \nolimits _{\mathscr{V}} {\vert \boldsymbol{\omega} \vert }^{2m} \hspace{0.167em} \mathrm{d} V$ with ${\varpi }_{0} = \nu {L}^{- 2} $. All four simulations unexpectedly show that the ${D}_{m} $ are ordered for $m= 1, \ldots , 9$ such that ${D}_{m+ 1} \lt {D}_{m} $. Moreover, the ${D}_{m} $ squeeze together such that ${D}_{m+ 1} / {D}_{m} \nearrow 1$ as $m$ increases. The values of ${D}_{1} $ lie far above the values of the rest of the ${D}_{m} $, giving rise to a suggestion that a depletion of nonlinearity is occurring which could be the cause of Navier–Stokes regularity. The first simulation is of very anisotropic decaying turbulence; the second and third are of decaying isotropic turbulence from random initial conditions and forced isotropic turbulence at fixed Grashof number respectively; the fourth is of very-high-Reynolds-number forced, stationary, isotropic turbulence at up to resolutions of $409{6}^{3} $.

The Rayleigh–Taylor instability of an inclined buoyant cylinder of one very viscous fluid rising through another is examined through linear stability analysis, numerical simulation and experiment. The stability analysis represents linear eigenmodes of a given axial wavenumber as a Fourier series in the azimuthal direction, allowing the use of separable solutions to the Stokes equations in cylindrical polar coordinates. The most unstable wavenumber k∗ is long-wave if both the inclination angle α and the viscosity ratio λ (internal/external) are small; for this case, k∗ ∝ max{α, (λ ln λ−1)1/2} and thus a small angle in experiments can have a significant effect for λ ≪ 1. As α increases, the maximum growth rate decreases and the upward propagation rate of disturbances increases; all disturbances propagate without growth if the cylinder is sufficiently close to vertical, estimated as α ≳ 70°. Results from the linear stability analysis agree with numerical calculations for λ = 1 and experimental observations. A point-force numerical method is used to calculate the development of instability into a chain of individual plumes via a complex three-dimensional flow. Towed-source experiments show that nonlinear interactions between neighbouring plumes are important for α ≳ 20° and that disturbances can propagate out of the system without significant growth for α ≳ 40°.