In an important contribution to scholarship on measuring democratic performance, Little and Meng suggest that bias among expert coders accounts for erosion in ratings of democratic quality and performance observed in recent years. Drawing on 19 waves of survey data on US democracy from academic experts and from the public collected by Bright Line Watch (BLW), this study looks for but does not find manifestations of the type of expert bias that Little and Meng posit. Although we are unable to provide a direct test of Little and Meng’s hypothesis, several analyses provide reassurance that expert samples are an informative source to measure democratic performance. We find that respondents who have participated more frequently in BLW surveys, who have coded for V-Dem, and who are vocal about the state of American democracy on Twitter are no more pessimistic than other participants.

Public health officials have faced resistance in their efforts to promote mask-wearing to counter the spread of COVID-19. One approach to promoting behavior change is to alert people to the fact that a behavior is common (a descriptive norm). However, partisan differences in pandemic mitigation behavior mean that Americans may be especially (in)sensitive to information about behavioral norms depending on the party affiliation of the group in question. In July–August 2020, we tested the effects of providing information to respondents about how many Americans, co-partisans, or out-partisans report wearing masks regularly on both mask-wearing intentions and on the perceived effectiveness of masks. Learning that a majority of Americans report wearing masks regularly increases mask-wearing intentions and perceived effectiveness, though the effects of this information are not distinguishable from other treatments.

European urban dark earth investigations have aided our understanding of Late Roman and early medieval populations and their activities. Deposits from two locations below Exeter Cathedral were compared in a geoarchaeological study and contrasting uses of space were identified. This supports the need for case-by-case investigations of urban deposits.

Conspiracy theories are central to political discourse in Venezuela and are widely supported. In the Americas Barometer Venezuela survey from 2016 to 2017, 54 percent of respondents expressed agreement for at least one of three political conspiracy narratives unsupported by evidence. Political loyalties to Chavismo or to the anti-Chavista opposition drive much conspiracy theory belief, but not all. Politically motivated reasoning pushes some citizens toward a given conspiracy narrative but others away. Other factors that are distinct from political loyalties, including low education levels, predispositions toward Manichaeanism and fatalism, and belief in the supernatural are associated with conspiracism. This article presents new data on conspiracy theory beliefs in Venezuela as well as analysis of its individual-level correlates, then discusses how the current Venezuelan political environment fosters conspiracy and what changes might mitigate this phenomenon.

When a party or candidate loses the popular vote but still wins the election, do voters view the winner as legitimate? This scenario, known as an electoral inversion, describes the winners of two of the last six presidential elections in the United States. We report results from two experiments testing the effect of inversions on democratic legitimacy in the US context. Our results indicate that inversions significantly decrease the perceived legitimacy of winning candidates. Strikingly, this effect does not vary with the margin by which the winner loses the popular vote, nor by whether the candidate benefiting from the inversion is a co-partisan. The effect is driven by Democrats, who punish inversions regardless of candidate partisanship; few effects are observed among Republicans. These results suggest that the experience of inversions increases sensitivity to such outcomes among supporters of the losing party.

Background: Prevention of central-line–associated bloodstream infections (CLABSIs) and methicillin-resistant Staphylococcus aureus (MRSA) infections requires a multifaceted approach including strategies to decrease cutaneous bacterial colonization. Prior studies have shown benefit from chlorhexidine-gluconate (CHG) skin application on CLABSI and MRSA infection rates in intensive care units (ICUs); however, the use of CHG in the non-ICU population has not been well studied. Methods: We performed a quasi-experimental before-and-after study to evaluate the use of daily 2% CHG wipes in non-ICU patients at a 1,000 bed acute-care teaching hospital beginning in November 2017. The study population included adult and pediatric patients with central venous catheters on non-ICU units, excluding patients on the following units: stem cell transplant and hematologic malignancy (these units had already established use of CHG skin application as a standard prior to the intervention), labor and delivery, and psychiatry. CHG was applied according to the manufacturer’s instruction by nurses or nurse aides and random monthly auditing of compliance was performed. NHSN CLABSI, hospital-onset MRSA bacteremia, and hospital-onset MRSA LabID rates were compared for the period 24 months before the intervention (November 1, 2015, through October 31, 2017) to the 24-month period after the intervention (November 1, 2017, through October 31, 2019) using a paired t test. Notably, the health system also discontinued the use of contact precautions for patients with MRSA (excluding MRSA from open, draining wounds) 11 months prior to onset of this intervention. Results: The CLABSI rate decreased by 26% from 0.594 events per 1,000 central-line days (n = 50) before the intervention to 0.438 events per 1,000 central-line days (n = 38) after the intervention (P = 0.19). The number of CLABSIs with gram-positive organisms also decreased by 29%. MRSA LabID rates decreased by 37% from 0.301 events per 1,000 patient days (n = 119) to 0.189 events per 1,000 patient days (n = 75) (P = 0.01). MRSA bacteremia rates decreased by 79% from 0.058 events per 1,000 patient days (n = 23) to 0.012 events per 1,000 patient days (n = 5) (P < 0.01). Compliance with the intervention was 83% (n = 225). Conclusions: Daily CHG skin application in non-ICU patients with central venous catheters is an effective strategy to prevent CLABSIs and MRSA infections. We observed a decrease in MRSA LabID and bacteremia rates despite discontinuation of contact precautions. These findings suggest that a horizontal prevention approach of daily CHG skin application may be an effective alternative to contact isolation to interrupt transmission of MRSA in hospitalized patients outside the ICU setting.

Funding: None

Disclosures: None

OBJECTIVES/GOALS: The North Carolina Translational and Clinical Sciences Institute (NC TraCS) supports faculty and staff in carrying out clinical and translational research at UNC-Chapel Hill. To better understand customer satisfaction and impact, a survey was administered among NC TraCS users. METHODS/STUDY POPULATION: NC TraCS has 13 program areas that range from Biostatistics to Community and Stakeholder Engagement. These programs provide services to faculty, staff, students, and outside researchers in the area of clinical and translational science. A customer feedback survey was administered in Spring 2019 to anyone who had used at least one NC TraCS service between March 1st, 2017 and February 28th, 2019. A total of 856 survey invitations were sent. The survey included questions around users’ perception of the ease of access, helpfulness, outcome, and promptness of the services received using 6-point Likert scale. The survey also addressed career impact, communications, and suggestions for improvement. RESULTS/ANTICIPATED RESULTS: We received 268 responses, (31% response). Majority of respondents were satisfied with Overall Helpfulness (95%), Outcome of Service (96%), Ease of Access (93%), and Promptness of Service (90%). They also noted that their careers had at least slightly improved in the following areas: Mentorship (76%), Research Methods (75%), Skill Development (77%), Research Direction (71%) and Collaboration (80%). Furthermore, 96% responded positively to returning to TraCS. The feedback received was shared with service administrators and NC TraCS leadership to identify areas of improvement and further strengthen their services. Concerns, when present, were addressed by service directors or the overall PI’s. DISCUSSION/SIGNIFICANCE OF IMPACT: Need to communicate expectations to customers the expected turn-around time for help emerged as a clear take-away. In response, TraCS leadership is working to improve staffing and workflows for efficient service delivery including expectation management, especially among the most popular services.

OBJECTIVES/GOALS: The goals of this evaluation were 1) to describe the pilot grant application cycle and processes at NC TraCS, 2) to illustrate the impact of pilot grants on extramural grant funding, and 3) to provide a framework for other institutions to utilize for the evaluation of pilot grant programs. METHODS/STUDY POPULATION: From 2009-2019 the NC TraCS pilot program funded 925 projects, varying from $2,000 to $100,000. Pilot grants are available to any researcher affiliated with the university as well as partner institutions and community stakeholders. For this evaluation we analyzed data on pilot applicants (demographics, type of pilot, funding status, resubmissions, etc.) and outcomes (extramural funding, publications, etc.) yielded from funded pilots. In addition to summary statistics, we also calculated return on investment (ROI) for the program as a whole and by specific grant type. We will use bibliometric network analysis to assess productivity, citation impact, and scope of collaboration. RESULTS/ANTICIPATED RESULTS: There have been 2,777 submitted proposals with an acceptance rate of 33.3%. Unfunded proposals can resubmit, 61.8% of resubmitted applications are successfully funded, and 29.6% of funded applications are resubmissions. The $2,000 awards accounted for 43.4% of all grants awarded but only accounted for 6.4% of all pilot funds awarded. Success of proposals was proportional to the number of applications from each academic unit. 60.8% of funded applicants were affiliated with the School of Medicine and account for 65.3% of all funding awarded from 2009-2019. Additionally, we plan on analyzing return on investment rates to illustrate the impact of pilot awards on future research funding. DISCUSSION/SIGNIFICANCE OF IMPACT: Pilot grants can lead to subsequent extramural grants, publications, and successful translation of research into practice. This evaluation will assist our institution in understanding the impact of pilot grants and will provide a road map for other institutions evaluating their own programs.