Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

5 results

  • 24 - Electroconvulsive therapy

  • from Section 4 - Specific modalities of treatment
  • Edited by J. John Mann, Columbia University, New York
  • Edited in association with Patrick J. McGrath, Columbia University, New York, Steven P. Roose, Columbia University, New York
  • Book:
    Clinical Handbook for the Management of Mood Disorders
    Published online:
    05 May 2013
    Print publication:
    09 May 2013, pp 311-324

  • Summary

    The detection and appropriate management of depression among women of reproductive age before or early in pregnancy is critical. The majority of studies have not found an association with major congenital malformations (MCMs) and first-trimester exposure to selective serotonin reuptake inhibitors (SSRIs). Non-SSRI and non-tricyclic antidepressants (TCA) antidepressants have been the focus of small studies. These medications include trazodone, mirtazapine, nefazodone, mianserin, and reboxetine. A neonatal behavioral syndrome (NBS) has been described in neonates exposed to antidepressants in utero. Lithium carbonate remains one of the mainstays for acute and maintenance treatment of bipolar disorder. There have been several registries that have collected information on the use of lamotrigine in the first trimester of pregnancy. A single case study found vagal nerve stimulation (VNS) to be safe during pregnancy in a woman receiving treatment throughout pregnancy, labor, and delivery.

  • The authors reply

  • JOAN PRUDIC, MARK OLFSON, HAROLD A. SACKEIM
  • Journal:
    Psychological Medicine / Volume 32 / Issue 7 / October 2002
    Published online by Cambridge University Press:
    21 October 2002, pp. 1321-1326

  • We thank Dr Abrams and Dr Fink for their comments on our article, ‘Electroconvulsive therapy practices in the community’ (Prudic et al. 2001). The major point of our paper was that there was considerable heterogeneity in the nature of ECT practices employed in hospitals in the New York City metropolitan region. Neither Dr Abrams nor Dr Fink disputes this, as the evidence was straight forward.

  • Who Responds to Electroconvulsive Therapy?: A Comparison of Effective and Ineffective Forms of Treatment

  • Christina Sobin, Joan Prudic, D. P. Devanand, Mitchell S. Nobler, Harold A. Sackeim
  • Journal:
    The British Journal of Psychiatry / Volume 169 / Issue 3 / September 1996
    Published online by Cambridge University Press:
    02 January 2018, pp. 322-328
    Print publication:
    September 1996
  • Background

    It has been reported that real ECT is more effective than simulated treatment among depressed patients with delusions and/or retardation, and that ECT is not effective among depressed patients who lack these features.

    Method

    In two randomised, double-blind studies, 143 patients with major depression were subtyped regarding psychosis, retardation and agitation. In both studies, low dosage, right unilateral ECT was ineffective compared with other forms of ECT. This report examined whether the depressive subtypes differed in clinical response to the ineffective and effective forms of ECT.

    Results

    The therapeutic advantage of effective forms of ECT was similar across the depression subtypes. Patients who lacked both psychosis and retardation showed this pattern.

    Conclusions

    The findings cast doubt on the utility of these depression subtypes in predicting ECT response. ECT is a viable treatment option for patients with major depression regardless of the presence or absence of psychosis, retardation and/or agitation.