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2 results

  • 23 - PROGERIA

  • from PART II: - HEREDITARY AND GENETIC CONDITIONS AND MALFORMATIONS
  • Edited by Louis R. Caplan, Julien Bogousslavsky
  • Book: Uncommon Causes of Stroke
  • Published online: 06 January 2010
  • Print publication: 09 October 2008, pp 145-148

  • Summary

    Pulmonary arteriovenous malformations (PAVMs) are rare occurrences among the population. These malformations can be acquired in various clinical settings or be congenital. Single PAVMs <2 cm in diameter may be asymptomatic. The severity of symptoms is believed to be proportionally related to the size (diameter) of the PAVMs. The specific anatomy of the vascular malformation must then be analyzed either with helical computed tomography (CT) or magnetic resonance angiography (MRA). Digital subtraction angiography is eventually performed. The aims of treatment are to prevent neurological complications and pulmonary hemorrhage and to improve hypoxemia. Lobectomy or pneumonectomy is performed only in rare situations such as in patients in whom the feeding artery is so short that there is a risk of coil migration. Embolization therapy is applied for PAVMs, and is carried out by transcatheter embolotherapy, which consists in obliterating the feeding artery.