In this study, Ag doped hydroxyapatite (HA) samples prepared by EDTA chelate
decomposition method were characterized with X-Ray Diffraction Spectroscopy
(XRD), Scanning Electron Microscopy (SEM) and antimicrobial sensitivity
test. Hydroxyapatite (Ca10(PO)6(OH)2) and
NaCaPO4 (rhenanite) phases were observed while Ag was present
in the form of Ag2O. Results showed that microstructurally
controlled HA-based composites with NaCaPO4 interphase can be
prepared, which significantly enhances sinterability of hydroxyapatite at
1100° C without formation of any undesired second phases, such as tricalcium
phosphate (TCP) known to decrease the stability of HA. The antibacterial
sensitivity was tested with E.Coli gram-negative bacteria. The radius of
circle enclosing the sample increases with increasing Ag content in the
structure as an indication of the region of non-bacterial activity.