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Proper nutritional management is important for the growth and development of children with motor or intellectual disabilities; however, few studies have investigated the nutrient intake of children with disabilities. This study aimed to investigate the nutrient intake and food groups that are the main sources of nutrients for children with disabilities. This cross-sectional observational study included twenty-five children (mean age, 11⋅8 years) from five hospitals in Japan. Using a 3-d weighed dietary record, we estimated the daily nutrient intake and food and beverage sources that contributed to nutrient intake. The mean values of calcium, magnesium, iron, vitamin A, thiamine, riboflavin, and vitamin C intake were below the recommended dietary allowance, and those of dietary fiber and potassium were below the levels recommended by the Tentative Dietary Goal for Preventing Lifestyle-related Diseases (DG). In contrast, the mean intake values of fat, saturated fatty acids, and sodium were above the DG levels. Dairy products, meat, vegetables, and cereals were found to be the major contributors of nutrients. Increased intake of vegetables may help alleviate insufficient micronutrient intake in children with disabilities.
We developed a simple and cost-effective method for extracting carbon from dissolved inorganic carbon (DIC) in water samples without a carrier gas. This method only slightly modifies the existing vacuum line for CO2 purification in radiocarbon research laboratories by connecting several reservoirs and traps. The procedure consists of repeated cycles of CO2 extraction from water into the headspace of the reaction container, expansion of the extracted gas into the vacuum line, and cryogenic trapping of CO2. High CO2 yield (∼98%) was obtained from a variety of water samples with a wide range of DIC concentrations (0.4–100 mmol·L−1, in the case of 1.2 mgC). The δ13C fractionation depended on the CO2 yield, while the 14C concentration was constant within the error range, regardless of the CO2 yield. The average δ13C discrepancy between the results of this method and direct analyses made using the GC-IRMS was 0.02 ± 0.06‰. The standard deviations (1σ) in fraction of modern carbon (F14C) ranged from 0.0002 to 0.0004 for waters below 0.01 of F14C, and below 0.8% of F14C values for waters above 0.1. We conclude that this method is useful for effectively extracting CO2 from DIC in water and yields accurate 14C data.
Biometric recognition technologies have become more important in the modern society due to their convenience with the recent informatization and the dissemination of network services. Among such technologies, face recognition is one of the most convenient and practical because it enables authentication from a distance without requiring any authentication operations manually. As far as we know, face recognition is susceptible to the changes in the appearance of faces due to aging, the surrounding lighting, and posture. There were a number of technical challenges that need to be resolved. Recently, remarkable progress has been made thanks to the advent of deep learning methods. In this position paper, we provide an overview of face recognition technology and introduce its related applications, including face presentation attack detection, gaze estimation, person re-identification and image data mining. We also discuss the research challenges that still need to be addressed and resolved.
Thorny lacewings (Rhachiberothidae) are currently distributed only within Africa, whereas they are prevalent in the fossil record of various Cretaceous ambers across the Northern Hemisphere, with a handful of the fossil records from some Eocene European ambers. Four rhachiberothid species in four extinct genera are known from the mid-Cretaceous amber of northern Myanmar. Here, we report further examples of the remarkable palaeodiversity of this group from the same amber deposit, adding the four new fossil genera and seven new species: Acanthoberotha cuspis gen. et sp. nov., Astioberotha falcipes gen. et sp. nov., Stygioberotha siculifera gen. et sp. nov., Uranoberotha chariessa gen. et sp. nov., Creagroparaberotha cuneata sp. nov., Micromantispa galeata sp. nov. and M. spicata sp. nov. Based on a series of well-preserved specimens, we discuss the fine details of the raptorial forelegs and genital segments, which may be important for elucidating the phylogenetic relationships among genera. Our findings reveal an unexpectedly diverse assemblage of thorny lacewings in the Cretaceous System, highlighting the morphologically diverse rhachiberothids in Burmese amber. The discovery of seven additional rhachiberothid species in Myanmar amber suggests the potential for much higher diversity and abundance of the Cretaceous rhachiberothids than previously documented. Furthermore, morphological variation in the raptorial forelegs was found to be extremely diverse among the Burmese amber paraberothines, especially in terms of the size, number and shape of spines (or spine-like setae) on the inner edges of protibia, and the morphological structure of the probasitarsus.
Thiamine deficiency (TD) is recognized in various kinds of disease with associated loss of appetite including cancer. However, it has not been recognized to date in bereaved partners after spousal loss from cancer.
Method
From a series of bereaved partners who lost a spouse to cancer, we report on those who developed TD after bereavement.
Result
Case 1 was a 57-year-old woman who sought consultation at our “bereavement clinic.” Her husband had been diagnosed with pancreatic cancer one year earlier and had died one month previously. At the first visit, she was observed to suffer depression, anxiety, and decreased appetite. Neurological, blood, and biochemical examinations did not reveal any noteworthy findings. She was diagnosed with uncomplicated bereavement. Detailed examination revealed that her appetite had been markedly decreased for approximately five weeks. The diagnosis of TD was supported by her abnormally low serum thiamine level. Case 2 was a bereaved 73-year-old male who had lost his wife to hypopharyngeal cancer one month previously after a five-year illness. He had shown a lack of energy for the month preceding his wife's death, but because there was no improvement after her death, his family recommended he seek consultation at our “bereavement clinic.” He was suffering from major depressive disorder. Detailed examination revealed that his appetite had been decreased for more than two weeks. Again, the diagnosis of TD was supported by his abnormally low serum thiamine level.
Significance of results
These reports demonstrate that there is a possibility that bereaved could develop TD after the loss of a loved one. TD should be considered whenever there is a loss of appetite lasting for more than 2 weeks, and medical staff should pay careful attention to the physical condition of the bereaved to prevent complications because of TD.
Amorphous Ta–O nanotubes (NTs) prepared by anodization in a sulfuric-acid-based solution have been found to contain considerable amounts of extra oxygen and sulfur. Their structural and thermal stability has been studied by combining x-ray diffractometry, transmission electron microscopy, and thermal analysis. The amorphous Ta–O, whose composition was estimated to be Ta2O6.6S0.7, crystallizes into orthorhombic β-Ta2O5 at temperatures around 1073 K by an endothermic reaction, at which excess oxygen and impurity sulfur are released. The amorphous NTs were found to be thermally more stable than stoichiometric amorphous Ta2O5, whose crystallization temperature is around 973 K. Excess oxygen and impurity sulfur, which form chemical bonds with Ta atoms in the amorphous solid, must be the origin of the stability. The crystallization follows the out-diffusion of oxygen and sulfur from the solid at temperatures where the mobility of atoms is high enough, indicating that the crystallization is kinetically arrested.
The 2011 Great East Japan Earthquake caused major disruptions in the provision of health care, including that for patients with sleep-disordered breathing (SDB) using a nasal continuous positive airway pressure (nCPAP) device. This study investigated the ability of SDB patients to continue using the nCPAP device in the weeks immediately following the earthquake, whether inability to use the nCPAP device led to symptom relapse, and measures that should be taken to prevent disruptions in nCPAP therapy during future disasters.
Hypothesis
If nCPAP devices cannot be used during disasters, SDB patients’ health will be affected negatively.
Methods
Within 14 days of the disaster, 1,047 SDB patients completed a questionnaire that collected data regarding ability to use, duration of inability to use, and reasons for inability to use the nCPAP device; symptom relapse while unable to use the nCPAP device; ability to use the nCPAP device use at evacuation sites; and recommendations for improvement of the nCPAP device.
Results
Of the 1,047 patients, 966 (92.3%) had been unable to use the nCPAP device in the days immediately following the earthquake. The most common reason for inability to use the nCPAP device was power failure, followed by anxiety about sleeping at night due to fear of aftershocks, involvement in disaster-relief activities, loss of the nasal CPAP device, and fear of being unable to wake up in case of an emergency. Among the 966 patients, 242 (25.1%) had experienced relapse of symptoms, the most common of which was excessive daytime sleepiness (EDS), followed by insomnia, headache, irritability, and chest pain.
Conclusion
Developing strategies for the continuation of nCPAP therapy during disasters is important for providing healthy sleeping environments for SDB patients in emergency situations.
MitoF, NishijimaT, SakuraiS, KizawaT, HosokawaK, TakahashiS, SuwabeA, AkasakaH, KobayashiS. Effects of CPAP Treatment Interruption Due to Disasters: Patients with Sleep-disordered Breathing in the Great East Japan Earthquake and Tsunami Area. Prehosp Disaster Med. 2013;28(6):547-555.
We have developed a new class of proton-conducting organic–inorganic hybrid silicophosphite membranes, produced by ethanol condensation of organically modified alkoxysilanes and anhydrous vinylphosphonic acid under solventless, catalyst-free, low-temperature, one-pot conditions. The membranes synthesized in this study are crack-free, large, and flexible, and they exhibit good thermal stability up to intermediate temperatures (~218 °C). Structural analyses using 29Si and 31P nuclear magnetic resonance spectroscopy and infrared measurements revealed that ethanol condensation produced an inorganic alternating copolymer structure, Si–O–P, with a phosphole group, and successive polymerization between vinyl and/or methacryl groups enabled these structures to connect with each other. In this way, it is possible to achieve structure manufacturing of inorganic–organic networks. The proton conductivities of the hybrids are as high as 5.2 × 10−3 S/cm at 85 °C under 80% relative humidity.
We performed accelerator mass spectrometry (AMS) radiocarbon dating and wiggle-matching of 2 wood samples from charred trunks of trees (samples A and B) collected from an ignimbrite deposit on the northeastern slope of the Baitoushan Volcano on the border of China and North Korea. The obtained calendar years for the eruption are cal AD 945–960 for sample A and cal AD 859–884 and cal AD 935–963 for sample B in the 2-σ range. These results are unable to determine the precise eruption age. The reason for the difference in reported ages may be due to volcanic gas emission prior to the huge eruption.
Previous studies of smoking on dopamine release in humans were investigated only in smokers. Using nicotine gum, we examined the effect of nicotine on dopamine release in smokers and non-smokers and its relation to the degree of nicotine dependence. Smokers and non-smokers participated in a double-blind, randomized, placebo-controlled cross-over study. They participated in two PET measurements with [11C]raclopride, in which they received either nicotine or placebo. Changes in [11C]raclopride non-displaceable binding potential (BPND) following nicotine administration were quantified. Smokers showed significant decrease in BP in the striatum following nicotine administration, but non-smokers did not show such a decrease. The BPND difference between the two scanning sessions was correlated with the degree of nicotine dependence. The BPND difference might reflect enhanced dopamine release in smokers and the reinforced effect of nicotine. These data suggest the feasibility of our gum method as well as the importance of the degree of dependence in future studies of the nicotine effect on the dopamine system.
To identify risk factors for infection and severe illness due to Chlamydia pneumoniae.
Methods.
To identify risk factors for infection, we conducted a case-control study among nursing home residents who had onset of symptoms during December 1, 1999, to February 20, 2000. To identify risk factors for severe illness among nursing home residents, we conducted a retrospective cohort study.
Setting.
A nursing home providing long-term and day care services for elderly patients in Japan.
Participants.
Fifty-nine residents and 41 staff members of a nursing home.
Results.
The attack rates for respiratory illness were 53% (31 of 59) among residents and 22% (9 of 41) among staff. Infection was confirmed in 15 resident and 2 staff case patients by isolation of C. pneumoniae from nasal swab specimens. Fifteen resident case patients developed severe illness (ie, bronchitis, pneumonia, and hypoxia); one case patient died. The median age of resident case patients was 87 years. We could identify neither the source of the outbreak nor significant risk factors for infection and severe illness in residents. However, residents with a higher level of physical activity were more likely to become infected, whereas older residents (aged more than 85 years) and those with a lower level of physical activity were more likely to develop severe illness (P>.05). Contact with residents was a risk factor for infection in staff (relative risk, undefined; P = .04).
Conclusions.
C. pneumoniae can cause large outbreaks of infection and severe illness among elderly persons, and its transmission is likely to be enhanced by close contacts among people in nursing homes. Therefore, early detection of an outbreak by means of better surveillance, and subsequent isolation of patients, may be effective control measures.
TEX101, a glycoprotein we recently identified, is primarily characterized as a unique germ-cell-specific marker protein that shows sexually dimorphic expression during mouse gonad development. Based on data obtained from molecular biological as well as immuno-morphological studies, we believe this molecule may play a role in the process underlying germ cell formation. However, many points remain unclear as the molecular characteristics and its physiological functions are far from being completely understood. To clarify the molecular basis of TEX101, we herein report a further biochemical characterization of the molecule using testicular Triton X-100 extracts from mice. Deglycosylation studies using endoglycohydrolases that delete N-linked oligosaccharides (OS) from the molecule show that TEX101 is highly (approximately 47%) N-glycosylated. All potential N-glycosylation sites within TEX101 are glycosylated and most of these sites are occupied by endoglycosidase F2-sensitive biantennary complex type OS units. In addition, an extremely low population among TEX101 possesses only endoglycosidase H-sensitive hybrid type OS units. In studies using phosphatidylinositol-specific phospholipase C against native testicular cells or TEX101 transfectant, the enzyme treatment caused major reduction of the TEX101 expression on the cell, suggesting that TEX101, at least in part, is expressed as a glycosylphosphatidylinositol-anchored protein. Taken together, these findings will help elucidate the molecular nature of TEX101, a marker molecule that appeared on germ cells during gametogenesis.
Transmission volume holograms recorded in two types of methacrylate-based photopolymer films that include benzyl n-butyl phthalate (BBP) or Poly(methyl methacrylate) (PMMA) are studied. It is shown that both BBP and PMMA molecules can be uniformly dispersed into methacrylate monomers and that a refractive index modulation as high as ∼0.005 is recorded by optimizing their volume concentrations. Moreover, it is also shown that the additional doping of silica nanoparticles substantially suppresses polymerization shrinkage without increasing optical scattering loss.