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Urine cytology specimens make up an important percentage of the nongynecologic case load in most cytopathology laboratories. This type of specimen has been labeled as “challenging” due to a lack of quantitative definition of adequacy, the subjective nature of “atypia”, marked degenerative changes seen especially in voided urine specimens, and the unrealistic expectation of making a low-grade urothelial carcinoma (LGUC) diagnosis.