To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The main aim of preimplantation genetic testing (PGT), which up until recently was known as preimplantation genetic diagnosis (PGD), is the identification of embryos that are free of inherited genetic conditions. PGT can therefore be considered as a treatment option for couples where one or both partners are at risk of transmitting such a condition to their offspring. Inherited genetic conditions can affect gene function or chromosome structure, and could either be present in families or arise de novo. PGT for inherited mutations affecting gene function is defined as PGT for monogenic disorders or PGT-M, whereas PGT for inherited chromosome rearrangements is termed as PGT for structural rearrangements or PGT-SR (). The selection and preferential transfer of healthy embryos could lead to the birth of babies who are free of the genetic disorder for which PGT was carried out, as well as potentially eradicate it from the family. Hence, PGT can be considered as an alternative form of prenatal diagnosis, with the added advantage that it avoids the termination of affected pregnancies.