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The focus of this chapter is women’s health and the unique domains of reproductive health and pregnancy. For women to be well, measures to prevent disease and to promote and optimize physical, mental, and social health should be widely adopted. Wellness measures should be consistent across the lifespan of women, from adolescence to reproductive age and into menopause. The roles of preventive health, recognition of disparities and improving health equity, and complementary and alternative medicine in optimizing women’s wellness are reviewed. Lifestyle includes changeable behaviors that can affect the individual’s health in the domains of nutrition, physical activity, stress, self-care, social relationships, and improper health behaviors . Globally the importance of activation of women’s empowerment, social networking, and accountability in women’s health should be considered.