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Within the Herschel key project “The Warm And Dense ISM” (WADI) we systematically observe
a number of prominent photon-dominated regions (PDRs) to measure the impact of varying UV
fields on the energy balance, the chemical and dynamical structure of heated molecular
The observational and theoretical information on the CO/H2 abundance in a variety of astrophysical regions including diffuse clouds, dense star-forming regions, shocked gas and circumstellar envelopes is discussed and reviewed.
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