A spacetime formulation is presented to solve unsteady aerodynamic problems involving large deformation or topological change such as store separation, slat and flap deployment or spoiler deflection. This technique avoids complex CFD meshing methods, such as Chimera, by the use of a finite-volume approach both in space and time, and permits a locally varying real timestep. The use of a central-difference scheme in the time direction can yield non-physical transient solutions as a consequence of information travelling backwards in time. Therefore, an upwind formulation is provided and validated against one-dimensional and two-dimensional test cases. A hybrid formulation (central in space, upwind in time) is also given and unsteady cases are computed for a spoiler and spoiler/flap deployment, with all three formulations compared, demonstrating that the use of an upwind time stencil yields more representative physical solutions and improves the rate of convergence.

The goal for many PhD students in archaeology is tenure-track employment. Students primarily receive their training by tenure-track or tenured professors, and they are often tacitly expected—or explicitly encouraged—to follow in the footsteps of their advisor. However, the career trajectories that current and recent PhD students follow may hold little resemblance to the ones experienced by their advisors. To understand these different paths and to provide information for current PhD students considering pursuing a career in academia, we surveyed 438 archaeologists holding tenured or tenure-track positions in the United States. The survey, recorded in 2019, posed a variety of questions regarding the personal experiences of individual professors. The results are binned by the decade in which the respondent graduated. Evident patterns are discussed in terms of change over time. The resulting portraits of academic pathways through the past five decades indicate that although broad commonalities exist in the qualifications of early career academics, there is no singular pathway to obtaining tenure-track employment. We highlight the commonalities revealed in our survey to provide a set of general qualifications that might provide a baseline set of skills and experiences for an archaeologist seeking a tenure-track job in the United States.

Global 21-cm experiments require exquisitely precise calibration of the measurement systems in order to separate the weak 21-cm signal from Galactic and extragalactic foregrounds as well as instrumental systematics. Hitherto, experiments aiming to make this measurement have concentrated on measuring this signal using the single element approach. However, an alternative approach based on interferometers with short baselines is expected to alleviate some of the difficulties associated with a single element approach such as precision modelling of the receiver noise spectrum. Short spacing Interferometer Telescope probing cosmic dAwn and epoch of ReionisAtion (SITARA) is a short spacing interferometer deployed at the Murchison Radio-astronomy Observatory (MRO). It is intended to be a prototype or a test-bed to gain a better understanding of interferometry at short baselines, and develop tools to perform observations and data calibration. In this paper, we provide a description of the SITARA system and its deployment at the MRO, and discuss strategies developed to calibrate SITARA. We touch upon certain systematics seen in SITARA data and their modelling. We find that SITARA has sensitivity to all sky signals as well as non-negligible noise coupling between the antennas. It is seen that the coupled receiver noise has a spectral shape that broadly matches the theoretical calculations reported in prior works. We also find that when appropriately modified antenna radiation patterns taking into account the effects of mutual coupling are used, the measured data are well modelled by the standard visibility equation.

The optimal timing of blood culture (BCx) sets collection has not been evaluated with continuous BCx detection systems. The yield of BCx was similar between short intervals (median, 3 minutes) and longer intervals (median, 16 or 43 minutes) among 5,856 BCx, except for improved polymicrobial bacteremia detection with long-interval BCx.

Many short gamma-ray bursts (GRBs) originate from binary neutron star mergers, and there are several theories that predict the production of coherent, prompt radio signals either prior, during, or shortly following the merger, as well as persistent pulsar-like emission from the spin-down of a magnetar remnant. Here we present a low frequency (170–200 MHz) search for coherent radio emission associated with nine short GRBs detected by the Swift and/or Fermi satellites using the Murchison Widefield Array (MWA) rapid-response observing mode. The MWA began observing these events within 30–60 s of their high-energy detection, enabling us to capture any dispersion delayed signals emitted by short GRBs for a typical range of redshifts. We conducted transient searches at the GRB positions on timescales of 5 s, 30 s, and 2 min, resulting in the most constraining flux density limits on any associated transient of 0.42, 0.29, and 0.084 Jy, respectively. We also searched for dispersed signals at a temporal and spectral resolution of 0.5 s and 1.28 MHz, but none were detected. However, the fluence limit of 80–100 Jy ms derived for GRB 190627A is the most stringent to date for a short GRB. Assuming the formation of a stable magnetar for this GRB, we compared the fluence and persistent emission limits to short GRB coherent emission models, placing constraints on key parameters including the radio emission efficiency of the nearly merged neutron stars ( $\epsilon_r\lesssim10^{-4}$ ), the fraction of magnetic energy in the GRB jet ( $\epsilon_B\lesssim2\times10^{-4}$ ), and the radio emission efficiency of the magnetar remnant ( $\epsilon_r\lesssim10^{-3}$ ). Comparing the limits derived for our full GRB sample (along with those in the literature) to the same emission models, we demonstrate that our fluence limits only place weak constraints on the prompt emission predicted from the interaction between the relativistic GRB jet and the interstellar medium for a subset of magnetar parameters. However, the 30-min flux density limits were sensitive enough to theoretically detect the persistent radio emission from magnetar remnants up to a redshift of $z\sim0.6$ . Our non-detection of this emission could imply that some GRBs in the sample were not genuinely short or did not result from a binary neutron star merger, the GRBs were at high redshifts, these mergers formed atypical magnetars, the radiation beams of the magnetar remnants were pointing away from Earth, or the majority did not form magnetars but rather collapse directly into black holes.

Capacity development is critical to long-term conservation success, yet we lack a robust and rigorous understanding of how well its effects are being evaluated. A comprehensive summary of who is monitoring and evaluating capacity development interventions, what is being evaluated and how, would help in the development of evidence-based guidance to inform design and implementation decisions for future capacity development interventions and evaluations of their effectiveness. We built an evidence map by reviewing peer-reviewed and grey literature published since 2000, to identify case studies evaluating capacity development interventions in biodiversity conservation and natural resource management. We used inductive and deductive approaches to develop a coding strategy for studies that met our criteria, extracting data on the type of capacity development intervention, evaluation methods, data and analysis types, categories of outputs and outcomes assessed, and whether the study had a clear causal model and/or used a systems approach. We found that almost all studies assessed multiple outcome types: most frequent was change in knowledge, followed by behaviour, then attitude. Few studies evaluated conservation outcomes. Less than half included an explicit causal model linking interventions to expected outcomes. Half of the studies considered external factors that could influence the efficacy of the capacity development intervention, and few used an explicit systems approach. We used framework synthesis to situate our evidence map within the broader literature on capacity development evaluation. Our evidence map (including a visual heat map) highlights areas of low and high representation in investment in research on the evaluation of capacity development.

Background: To assess the response to high dose daily nocturnal diazepam (HDD) in children with encephalopathy associated with electrical status epilepticus in sleep (ESES). Methods: A prospective cohort of patients (4-12 years), newly diagnosed with ESES, initiated on the first course HDD, was followed for ≤ 1-year. Sleep EEG scores (SES) pre and post HDD were evaluated. An EEG grading system based on both sleep spike wave index (sSWI) (Grade: 1-4) and distribution of epileptiform discharges (Grade: 0-4) was used and summed to yield an aggregate SES (ASES) (Grade: 1-8). Results: Eighteen eligible children (M:F 12:6; median age, 7.6 years) were initiated on first course HDD (median, 0.5 mg/kg/d). sSWI decreased from 85.7% (mean, SD 13.9) to 32.6% (mean, SD 37.1) at subsequent EEG (95% CI = -70.60- -35.62; p < 0.001). ASES decreased from 6.5 (SD 1.3) to 3.1 (SD 1.9) (95% CI = -4.17- -2.60; p < 0.001). EEG relapse after a period of improvement occurred in 10 children. Minimal response to HDD occurred in 2 children. Five patients manifested mild side effects; behavior (2), hyperactivity (2), and lethargy (1). Conclusions: HDD safely and significantly reduces both SWI and aggregate sleep EEG score in children with ESES.

Background: Repetitive sub-concussive head impacts have been associated with changes in brain architecture and neurological symptoms. In this study, we examined the association between repetitive sub-concussive impacts, impact burden, and blood brain barrier (BBB) integrity in university football players. Methods: 59 university football players were followed over the 2019 season. Athletes with diagnosed concussion and those sustaining impacts that alerted a sideline impact monitor (relayed by ferroelectric helmet sensors) underwent dynamic contrast-enhanced MRI (DCE-MRI) within one week of injury/alert, and 4 weeks following initial incident. Results: Helmets recorded 2648 impacts over 48 cumulative hours. 8 concussions occurred during the 2019 season (2.82 per 1000 activity hours). On average, athletes with a diagnosed concussion had 55.3 impacts to the front sensor, compared to 14.1 in non-concussed athletes. Athletes who consented to DCE-MRI (n=5) had 10.78% BBB-D within a week of concussion/alert, and 6.77% BBB-D at 4-weeks. Conclusions: We show quantification of BBB integrity relative to head impact burden for the first time. This preliminary study highlights the potential of impact-detecting helmets to provide relevant impact characteristics and offers a foundation for future work on neurological consequences of repetitive sub-concussive impacts.

The Variables and Slow Transients Survey (VAST) on the Australian Square Kilometre Array Pathfinder (ASKAP) is designed to detect highly variable and transient radio sources on timescales from 5 s to $\sim\!5$ yr. In this paper, we present the survey description, observation strategy and initial results from the VAST Phase I Pilot Survey. This pilot survey consists of $\sim\!162$ h of observations conducted at a central frequency of 888 MHz between 2019 August and 2020 August, with a typical rms sensitivity of $0.24\ \mathrm{mJy\ beam}^{-1}$ and angular resolution of $12-20$ arcseconds. There are 113 fields, each of which was observed for 12 min integration time, with between 5 and 13 repeats, with cadences between 1 day and 8 months. The total area of the pilot survey footprint is 5 131 square degrees, covering six distinct regions of the sky. An initial search of two of these regions, totalling 1 646 square degrees, revealed 28 highly variable and/or transient sources. Seven of these are known pulsars, including the millisecond pulsar J2039–5617. Another seven are stars, four of which have no previously reported radio detection (SCR J0533–4257, LEHPM 2-783, UCAC3 89–412162 and 2MASS J22414436–6119311). Of the remaining 14 sources, two are active galactic nuclei, six are associated with galaxies and the other six have no multi-wavelength counterparts and are yet to be identified.

Established chronologies indicate a long-term ‘Hoabinhian’ hunter-gatherer occupation of Mainland Southeast Asia during the Terminal Pleistocene to Mid-Holocene (45 000–3000 years ago). Here, the authors re-examine the ‘Hoabinhian’ sequence from north-west Thailand using new radiocarbon and luminescence data from Spirit Cave, Steep Cliff Cave and Banyan Valley Cave. The results indicate that hunter-gatherers exploited this ecologically diverse region throughout the Terminal Pleistocene and the Pleistocene–Holocene transition, and into the period during which agricultural lifeways emerged in the Holocene. Hunter-gatherers did not abandon this highland region of Thailand during periods of environmental and socioeconomic change.

Light curves of photospheric radius expansion (PRE) bursts, a subset of type I X-ray bursts, have been used as standard candles to estimate the ‘nominal PRE distances’ for 63% of PRE bursters (bursters), assuming PRE burst emission is spherically symmetric. Model-independent geometric parallaxes of bursters provide a valuable chance to test models of PRE bursts (PRE models) and can be provided in some cases by Gaia astrometry of the donor stars in bursters. We searched for counterparts to 115 known bursters in the Gaia Early Data Release 3 and confirmed 4 bursters with Gaia counterparts that have detected ( $\gt\!3\,\sigma$ , prior to zero-point correction) parallaxes. We describe a generic approach to the Gaia parallax zero point as well as its uncertainty using an ensemble of Gaia quasars individually determined for each target. Assuming the spherically symmetric PRE model is correct, we refined the resultant nominal PRE distances of three bursters (i.e. Cen $\textrm{X}-4$ , Cyg $\textrm{X}-2$ , and $4\textrm{U}\,0919-54$ ) and put constraints on their compositions of the nuclear fuel powering the bursts. Finally, we describe a method for testing the correctness of the spherically symmetric PRE model using parallax measurements and provide preliminary results.