Losses of pigs (dead and non-ambulatory) during transport are of great concern from both animal welfare and also economic perspectives. Based on several field studies, we have reported the incidence of transport losses in market weight pigs to be ~1% (Ellis et al. , 2003). Transport losses can be influenced by numerous factors including genetics, carcass muscling, health status, structural soundness, live weight, nutrition, handling, facility design, and conditions during transport to the plant. Few, if any, of these factors have been examined under typical commercial conditions. Floor space on the trailer during transport is a potential contributing factor that can be easily changed by varying the number of pigs placed on the truck and represents a simple approach to managing transport losses. The objective of this study was to investigate effects of two floor spaces (0.39 and 0.48 m2/pig) during transport, that represent the range currently being used in commercial practice in the U.S., on the incidence of dead and non-ambulatory pigs and to evaluate relationships between transport conditions and transport losses.