To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The most important purpose of embryo culture in the IVF lab is to make sure that the embryo can develop to its full potential in a safe and secure environment, and to prevent any errors that can lead to cancellation of the IVF cycle, or risk of other adverse outcomes. In a study by Sakkas et al. (2018),1 including data from over 10 years and more than 35,000 fresh and frozen IVF cycles from more than 180,000 individual laboratory procedures, it was shown that the rate of moderate nonconformances was 0.23%. These failures are described as problems that negatively affect a cycle but not to the extent that the cycle is lost or severely compromised. Although the data from this study is reassuring and shows a very low rate of nonconformance during treatment, the most undesirable and catastrophic event that can occur in an IVF laboratory is a misidentification and mix-up of sperm, egg, or embryo. Embryo culture is a lengthy process that can last up to 6 or even 7 days in which the culture dish is manipulated regularly, sometimes on a daily basis, for purposes such as fertilization, embryo quality assessment, transfer, and cryopreservation. During these manipulations stringent procedures and protocols have to be in place in order to track and trace each and every embryo throughout the embryo culture. The ESHRE guideline for good practice in IVF laboratories includes a section on identification of patients and traceability of their reproductive cells.2 Although traceability is part of the quality management systems in IVF laboratories today, there is not one system that is fail-safe.
Email your librarian or administrator to recommend adding this to your organisation's collection.