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Adhesive contact between a thin elastic sheet and a substrate arises in a range of biological, physical and technological applications. By considering the dynamics of this process that naturally couples fluid flow, long-wavelength elastic deformations and microscopic adhesion, we analyse a sixth-order thin-film equation for the short-time dynamics of the onset of adhesion and the long-time dynamics of a steadily propagating adhesion front. Numerical solutions corroborate scaling laws and asymptotic analyses for the characteristic waiting time for adhesive contact and for the speed of the adhesion front. A similarity analysis of the governing partial differential equation further allows us to determine the shape of a fluid-filled blister ahead of the adhesion front. Finally, our analysis reveals a near-singular behaviour at the moving elastohydrodynamic contact line with an effective boundary condition that might be useful in other related problems.
Gravitational settling of a droplet in air onto a soft substrate is a ubiquitous event relevant to many natural processes and engineering applications. We study this phenomenon by developing a three-phase lubrication model of droplet settling onto a solid substrate coated by a thin soft layer represented by a viscous film, an elastic compressible layer and an elastic sheet supported by a viscous film. By combining scaling analysis, analytical methods and numerical simulations we elucidate how the resulting droplet dynamics is affected by the nature of the soft layer. We show that these soft layers can significantly affect the droplet shape during gravitational settling. When there is a linear response of the deformations of the soft layer, the air layer takes longer to drain as compared with the case of a droplet settling onto a rigid substrate. Our results provide new insight into the coupled interactions between droplets and solids coated by a thin film of a soft material.
To examine the variety of fruits and vegetables lower income households in the USA can buy while meeting Federal dietary recommendations at different levels of expenditure.
Design:
Simulation techniques were used to create 3000 market baskets of fruits and vegetables. All baskets contained enough food for a four-person household to meet dietary recommendations for fruits and vegetables over 1 week. Each basket’s retail value was estimated along with the ability of a representative household to afford each basket with different levels of expenditure.
Setting:
We used data from the US Department of Agriculture’s (USDA) Fruit and Vegetable Prices data product which reports a US household’s costs to buy each of 157 different fruit and vegetable products per edible cup equivalent.
Participants:
We consider the situation facing a lower income household that receives maximum benefits through the Supplemental Nutrition Assistance Program (SNAP). These benefits are enough for the household to obtain a nutritious and palatable diet without spending any of its own money on food if it approximately follows USDA’s Thrifty Food Plan.
Results:
Households receiving maximum SNAP benefits can buy a sufficient variety and quantity of fruits and vegetables if they allocate about 40 % of those benefits to these two food groups. However, if households spend less than that amount, the variety of products they can buy while still satisfying recommendations drops off quickly.
Conclusion:
Households that move fruits and vegetables to the centre of their budgets can better afford to meet Federal dietary guidelines.
The Patient-Centered Outcomes Research Institute (PCORI) horizon scanning system is an early warning system for healthcare interventions in development that could disrupt standard care. We report preliminary findings from the patient engagement process.
Methods
The system involves broadly scanning many resources to identify and monitor interventions up to 3 years before anticipated entry into U.S. health care. Topic profiles are written on included interventions with late-phase trial data and circulated with a structured review form for stakeholder comment to determine disruption potential. Stakeholders include patients and caregivers recruited from credible community sources. They view an orientation video, comment on topic profiles, and take a survey about their experience.
Results
As of March 2020, 312 monitored topics (some of which were archived) were derived from 3,500 information leads; 121 met the criteria for topic profile development and stakeholder comment. We invited fifty-four patients and caregivers to participate; thirty-nine reviewed at least one report. Their perspectives informed analyst nominations for fourteen topics in two 2019 High Potential Disruption Reports. Thirty-four patient stakeholders completed the user-experience survey. Most agreed (68 percent) or somewhat agreed (26 percent) that they were confident they could provide useful comments. Ninety-four percent would recommend others to participate.
Conclusions
The system has successfully engaged patients and caregivers, who contributed unique and important perspectives that informed the selection of topics deemed to have high potential to disrupt clinical care. Most participants would recommend others to participate in this process. More research is needed to inform optimal patient and caregiver stakeholder recruitment and engagement methods and reduce barriers to participation.
We study the dynamic wetting of a self-propelled viscous droplet using the time-dependent lubrication equation on a conical-shaped substrate for different cone radii, cone angles and slip lengths. The droplet velocity is found to increase with the cone angle and the slip length, but decrease with the cone radius. We show that a film is formed at the receding part of the droplet, much like the classical Landau–Levich–Derjaguin film. The film thickness $h_f$ is found to decrease with the slip length $\lambda$. By using the approach of matching asymptotic profiles in the film region and the quasi-static droplet, we obtain the same film thickness as the results from the lubrication approach for all slip lengths. We identify two scaling laws for the asymptotic regimes: $h_fh''_o \sim Ca^{2/3}$ for $\lambda \ll h_f$ and $h_f h''^{3}_o\sim (Ca/\lambda )^2$ for $\lambda \gg h_f$; here, $1/h''_o$ is a characteristic length at the receding contact line and $Ca$ is the capillary number. We compare the position and the shape of the droplet predicted from our continuum theory with molecular dynamics simulations, which are in close agreement. Our results show that manipulating the droplet size, the cone angle and the slip length provides different schemes for guiding droplet motion and coating the substrate with a film.
If a droplet smaller than the capillary length is placed on a substrate with a conical shape, it spreads by itself in the direction of growing fibre radius. We describe this capillary spreading dynamics by developing a lubrication flow approximation on a cone and by using the perturbation method of matched asymptotic expansions. Our results show that the droplet appears to adopt a quasi-static shape and the predictions of the droplet shape and the spreading velocity from the two mathematical models are in excellent agreement. At the contact line regions, a large pressure gradient is generated by the mismatch between the equilibrium contact angle and the apparent contact angle that maintains the viscous flow. It is the conical shape of the substrate that breaks the front/rear droplet symmetry in terms of the apparent contact angle, which is larger at the thicker part of the cone than at its thinner part. Consequently, the droplet is predicted to move from the cone tip to its base, consistent with experimental observations.
In this theoretical and numerical study, we show how spatially extended fluctuations can influence and dominate the dynamics of a fluid filled elastic blister as it deforms onto a pre-wetted solid substrate. To describe the blister dynamics, we develop a stochastic elastohydrodynamic framework that couples the viscous flow, the elastic bending of the interface and the noise from the environment. We deploy a scaling analysis to find the elastohydrodynamic spreading law $\hat{R}\sim \hat{t}^{1/11}$, where $\hat{R}$ is the spreading radius and $\hat{t}$ is time, a direct analogue to the capillary spreading of drops, while the inclusion of noise in our model highlights that the dynamics speeds up significantly $\hat{R}\sim \hat{t}^{1/6}$ as local changes in curvature at the spreading front enhance the peeling of the elastic interface from the substrate. These fluctuations have a pronounced influence on the shape of the deforming blister and lead to the formation of a precursor film similar to a perfectly wetting droplet. Moreover, our analysis identifies a distinct criterion for the transition between the deterministic and the stochastic spreading regime, which is further illustrated by numerical simulations.
We consider the wetting of water droplets on substrates with different chemical composition and molecular spacing, but with an identical equilibrium contact angle. A combined approach of large-scale molecular dynamics simulations and a continuum phase field model allows us to identify and quantify the influence of the microscopic physics at the contact line on the macroscopic droplet dynamics. We show that the substrate physico-chemistry, in particular hydrogen bonding, can significantly alter the flow. Since the material parameters are systematically derived from the atomistic simulations, our continuum model has only one adjustable parameter, which appears as a friction factor at the contact line. The continuum model approaches the atomistic wetting rate only when we adjust this contact line friction factor. However, the flow appears to be qualitatively different when comparing the atomistic and continuum models, highlighting that non-trivial continuum effects can come into play near the interface of the wetting front.
An important debate in the literature is whether or not higher energy-dense foods are cheaper than less energy-dense foods. The present communication develops and applies an easy statistical test to determine if the relationship between food price and energy density is an artifact of how the data units are constructed (i.e. is it ‘spurious’ or ‘real’?).
Design
After matching data on 4430 different foods from the National Health and Nutrition Examination Survey with corresponding prices from the Center for Nutrition Policy and Promotion’s Food Prices Database, we use a simple regression model to test if the relationship between food price and energy density is ‘real’ or ‘spurious’.
Setting
USA.
Subjects
Total sample size is 4430 observations of consumed foods from 4578 participants from the non-institutionalized US adult population (aged 19 years and over).
Results
Over all 4430 foods, the null hypothesis of a spurious inverse relationship between food price per energy density and energy density is not rejected. When the analysis is broken down by twenty-five food groups, there are only two cases where the inverse relationship is not spurious. In fact, the majority of non-spurious relationships between food price and energy density are positive, not negative.
Conclusions
One of the main arguments put forth regarding the poor diet quality of low-income households is that high energy-dense food is cheaper than lower energy-dense food. We find almost no statistical support for higher energy-dense food being cheaper than low energy-dense food. While economics certainly plays a role in explaining low nutritional quality, more sophisticated economic arguments are required and discussed.