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2 results

  • Fifty Years of Motor Unit Number Estimation

  • Regan D. Wright, Allison Sivak, Agessandro Abrahão, Kelvin E. Jones
  • Journal:
    Canadian Journal of Neurological Sciences / Volume 50 / Issue 1 / January 2023
    Published online by Cambridge University Press:
    01 December 2021, pp. 109-111
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  • The objective was to use bibliometric analysis to create an infographic of motor unit number estimation methods over the past 50 years. The original method was published in 1971, but secondary and tertiary waves of research using alternative methods occurred in the early 2000s and a decade later. A metric of influence was used to determine if different methods had clear peaks of use over the past 50 years. While the original method continues to register influence, the MUNIX method introduced in 2004 stands out as the most influential method to estimate the innervation status of skeletal muscles.

  • Effects of prenatal artificial sweeteners consumption on birth outcomes: a systematic review and meta-analysis

  • Chenxi Cai, Allison Sivak, Margie H Davenport
  • Journal:
    Public Health Nutrition / Volume 24 / Issue 15 / October 2021
    Published online by Cambridge University Press:
    14 January 2021, pp. 5024-5033
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  • Objective:

    To examine the influence of prenatal artificial sweetener (AS) consumption on birth outcomes.

    Design:

    Systematic review and meta-analysis.

    Setting:

    Online databases (Medline, CINAHL, Embase, Cochrane Library, Scopus, Web of Science, FSTA – the food resource database, and ClinicalTrials.gov) were searched up to 9 April 2020. Studies of all designs (except case studies and reviews) were eligible, which contained information on the relevant population (pregnant women), intervention/exposure (any AS consumption), comparator (no AS consumption) and birth outcomes (preterm delivery, gestational age, birth weight).

    Results:

    From 677 citations, ten cohort studies and one randomised controlled trial (n 138 007 women) were included. ‘Low’ to ‘very low’ certainty evidence revealed that daily consumption of AS was associated with an increased risk of preterm delivery (three studies, n 129 009; risk ratio = 1·18, 95 % CI 1·09, 1·28, I2 = 9 %), a 24 g increase in birth weight (three studies, n 64 417; mean difference (MD): 23·74 g, 95 % CI 0·89, 45·58, I2 = 0 %) and a 0·11 week decrease in gestational age (three studies, n 64 417; MD: –0·11 weeks, 95 % CI –0·19, –0·03, I2 = 0 %).

    Conclusions:

    ‘Low’ to ‘very low’ certainty evidence suggests daily AS consumption during pregnancy is associated with an increased risk of preterm delivery, increased birth weight and decreased gestational age. Additional ‘high’-quality research is urgently needed to further assess these relationships.

    PROSPERO registration number: CRD42019136728.