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This comprehensive yet practical text reviews the pathology of neoplastic and non-neoplastic conditions of the pleura and peritoneum, with a particular focus on mesothelioma. The anatomy and embryology of serous membranes are discussed, and the causes, epidemiology, and clinical and radiologic features of malignant mesothelioma are reviewed. A comprehensive review of immunostains used for diagnosing serous membrane lesions is given, current treatment options for patients are outlined. The markers of asbestos exposure and their significance are also assessed. The pathology of non-neoplastic conditions of serous membranes, from peritoneal cysts and endometriosis to deciduosis and gliomatosis peritonei are also covered, as are lymphomas and soft tissue tumors in serous membranes. This makes Practical Pathology of Serous Membranes an essential resource for effective diagnosis.
This book provides a comprehensive, up-to-date review of the pathology of the neoplastic and non-neoplastic diseases that occur in the mediastinum. The pathologic and relevant clinical features are discussed, and detailed diagnostic criteria for various diseases are given, along with information about the most relevant laboratory tests. The features of thymomas, thymic carcinomas, neuroendocrine carcinomas and germ cell tumors are discussed in detail, including the utilization of immunostains and other ancillary tests in diagnosing these diseases. An algorithmic approach to the differential diagnosis of mediastinal lymphomas is given, and a novel clinico-pathologic classification helps readers diagnose and treat thymomas. Cardiac lesions, mesothelioma and other intrathoracic lesions are also reviewed. The book features more than 650 images, and downloadable copies of these are included on a CD-ROM, packaged with the print book. Pathology of the Mediastinum will be of interest to practising surgical pathologists, thoracic surgeons, oncologists and radiologists.
The mediastinum is an anatomical area of great interest to pathologists, pulmonologists, radiologists, thoracic surgeons, and oncologists as it can be the site of origin of a surprisingly large number of neoplastic and non-neoplastic conditions. The two editors and several other surgical pathologists with many years of experience in the diagnosis of thymic neoplasms, malignant mesothelioma, soft tissue lesions, lymphomas, cardiac lesions, and other mediastinal lesions have collaborated with a multidisciplinary team of physicians that includes an experienced thoracic surgeon, cardiac pathologists, radiologists, and a clinical pathologist to provide a comprehensive review of mediastinal pathology.
The book includes a review of the anatomy of the mediastinum and its various structures and a concise yet informative discussion of the diagnosis of various mediastinal lesions by imaging methods. The embryology, anatomy, and pathophysiology of the thymus are reviewed in detail, followed by a comprehensive and well-illustrated description of the various non-neoplastic conditions that can arise in the thymus.