Development of high-efficiency solar cell modules and new application fields are significant for the further development of photovoltaics (PV) and creation of new clean energy infrastructure based on PV. Especially, development of PV-powered EV applications is desirable and very important for this end. This paper shows analytical results for efficiency potential of various solar cells for choosing candidates of high-efficiency solar cell modules for automobile applications. As a result of analysis, Si tandem solar cells are thought to be some of their candidates. This paper also overviews efficiency potential and recent activities of various Si tandem solar cells such as III-V/Si, II-VI/Si, chalcopyrite/Si, perovskite/Si and nanowire/Si tandem solar cells. The III-V/Si tandem solar cells are expected to have a high potential for various applications because of high efficiency with efficiencies of more than 36% for 2-junction and 42 % for 3-junction tandem solar cells under 1-sun AM1.5 G, lightweight and low-cost potential. Recent results for our 28.2 % efficiency and Sharp’s 33% mechanically stacked InGaP/GaAs/Si 3-junction solar cell are also presented. Approaches to automobile application by using III-V/Si tandem solar cells and static low concentration are presented.