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20 results

  • 12 - Effects on Brain Function

  • from Section 2 - Targeting Effects
  • Edited by Pedro L. Gambús, Jan F. A. Hendrickx
  • Book:
    Personalized Anaesthesia
    Published online:
    03 December 2019
    Print publication:
    06 February 2020, pp 175-196

  • Summary

    Surgery and anaesthesia alter the function of the brain and its control mechanisms. In the operating room, we daily observe the effects of anaesthetic agents during induction and recovery from anaesthesia: changes in the electroencephalogram, on consciousness, muscle tone as well as in the responses to different stimulations that immediately disappear after induction, and reappear gradually when anaesthetic effects wear off. To prevent short- or long-term functional changes of the brain, the parameters of its physiological defence mechanisms must be maintained within the patient’s normal range. Failing to do so might lead to complications that can significantly alter patient outcome.

Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care
  • 2nd edition
  • Edited by Arun Gupta, Adrian Gelb, Derek Duane, Ram Adapa
  • Published online:
    19 June 2018
    Print publication:
    21 June 2018
  • This updated second edition of Gupta and Gelb's Essentials of Neuroanesthesia and Neurointensive Care contains the ideal combination of updated information for the practitioner, presented in easy-to-digest short chapters. With an essential clinical focus on key neuroanesthesia and neurointensive care knowledge, it is a practical guide for any practitioner of neuroanesthesia, beginner, occasional or experienced. The user-friendly format contains bullet points to ensure retention of important data, key points to summarize the take-home messages, suitable images to enhance understanding, and pertinent and appropriate references to allow for further exploration of the topics. This book is ideal for residents and others undergoing neuroanesthesia training. It is also a great tool for Operating Room nurses and other OR support workers, neurosurgical residents and neurointensive care professionals. This will also be a useful book to supplement knowledge for postgraduate fellowship and Board examinations.

  • Anesthesia for Temporal Lobe Epilepsy Surgery

  • Ian A. Herrick, Adrian W. Gelb
  • Journal:
    Canadian Journal of Neurological Sciences / Volume 27 / Issue S1 / May 2000
    Published online by Cambridge University Press:
    02 December 2014, pp. S64-S67
    • Article
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  • Anesthetic considerations for temporal lobectomy for refractory epilepsy include ensuring a safe and comfortable perioperative experience for the patient, providing suitable operating conditions for the surgeon, avoiding interference with intraoperative electrocorticographic (ECoG) recordings and facilitating intraoperative functional cortical mapping, if performed. Providing the conditions that simultaneously meet these requirements, using general anesthesia or local anesthesia with sedation, remains a significant challenge for the neuroanesthetist. We review issues pertinent to the choice of anesthetic technique for these procedures.

  • 22 - Anaesthesia for neurosurgery

  • Edited by Ann Møller, KAS Herlev, Copenhagen, Tom Pedersen, Rigshospitalet, Copenhagen
  • Book:
    Evidence-based Anaesthesia and Intensive Care
    Published online:
    05 September 2009
    Print publication:
    09 October 2006, pp 282-292

  • Summary

    This chapter reviews basic neurophysiological principles and specific approaches to the management of intracranial pressure (ICP) as they relate to clinical neuroanaesthesia. It also reviews intraoperative management of the patient with a supratentorial mass lesion. There are six interrelated components that are important to the practice of neuroanaesthesia. They are maintenance of cerebral perfusion pressure (CPP), cerebral blood flow (CBF), cerebral blood volume (CBV), intracranial pressure (ICP), CO2 responsiveness (CO2R) and cerebral oxygen metabolism (CMRO2). The common types of neurosurgery can be divided into excision of intracranial mass lesions, especially supratentorial tumours, decompressive procedures in major head trauma and aneurysm clipping. The chapter focuses on managing elevated ICP as this is a problem common to all types of intracranial surgery, and then specifically the management of supratentorial masses. Management of the patient for neurosurgery requires a good understanding of the interrelationships of neurophysiology, pathophysiology and pharmacology.

  • Postoperative cognitive deficits: more questions than answers

  • G. Burkhard Mackensen, Adrian W. Gelb
  • Journal:
    European Journal of Anaesthesiology / Volume 21 / Issue 2 / February 2004
    Published online by Cambridge University Press:
    23 December 2004, pp. 85-88
    Print publication:
    February 2004
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