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5 results

  • Symptom monitoring after coronavirus disease 2019 (COVID-19) vaccination in a large integrated healthcare system: Separating symptoms from severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection

  • Erica S. Shenoy, Paige G. Wickner, Lauren R. West, Aleena Banerji, Kimberly G. Blumenthal, Amanda J. Centi, Andrew Gottlieb, Dean M. Hashimoto, Esther Kim, Marvel Kim, Hang Lee, Lynn A. Simpson, Adam B. Landman
  • Journal:
    Infection Control & Hospital Epidemiology / Volume 43 / Issue 10 / October 2022
    Published online by Cambridge University Press:
    02 November 2021, pp. 1439-1446
    Print publication:
    October 2022
  • Objective:

    To describe the incidence of systemic overlap and typical coronavirus disease 2019 (COVID-19) symptoms in healthcare personnel (HCP) following COVID-19 vaccination and association of reported symptoms with diagnosis of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) infection in the context of public health recommendations regarding work exclusion.

    Design:

    This prospective cohort study was conducted between December 16, 2020, and March 14, 2021, with HCP who had received at least 1 dose of either the Pfizer-BioNTech or Moderna COVID-19 vaccine.

    Setting:

    Large healthcare system in New England.

    Interventions:

    HCP were prompted to complete a symptom survey for 3 days after each vaccination. Reported symptoms generated automated guidance regarding symptom management, SARS-CoV-2 testing requirements, and work restrictions. Overlap symptoms (ie, fever, fatigue, myalgias, arthralgias, or headache) were categorized as either lower or higher severity. Typical COVID-19 symptoms included sore throat, cough, nasal congestion or rhinorrhea, shortness of breath, ageusia and anosmia.

    Results:

    Among 64,187 HCP, a postvaccination electronic survey had response rates of 83% after dose 1 and 77% after dose 2. Report of ≥3 lower-severity overlap symptoms, ≥1 higher-severity overlap symptoms, or at least 1 typical COVID-19 symptom after dose 1 was associated with increased likelihood of testing positive. HCP with prior COVID-19 infection were significantly more likely to report severe overlap symptoms after dose 1.

    Conclusions:

    Reported overlap symptoms were common; however, only report of ≥3 low-severity overlap symptoms, at least 1 higher-severity overlap symptom, or any typical COVID-19 symptom were associated with infection. Work-related restrictions for overlap symptoms should be reconsidered.

  • Using magnetic activity and Galactic dynamics to constrain the ages of M dwarfs

  • Andrew A. West, Suzanne L. Hawley, John J. Bochanski, Kevin R. Covey, Adam J. Burgasser
  • Journal:
    Proceedings of the International Astronomical Union / Volume 4 / Issue S258 / October 2008
    Published online by Cambridge University Press:
    01 October 2008, pp. 327-336
    Print publication:
    October 2008
    • Article
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  • We present a study of the dynamics and magnetic activity of M dwarfs using the largest spectroscopic sample of low-mass stars ever assembled. The age at which strong surface magnetic activity (as traced by Hα) ceases in M dwarfs has been inferred to have a strong dependence on mass (spectral type, surface temperature) and explains previous results showing a large increase in the fraction of active stars at later spectral types. Using spectral observations of more than 40000 M dwarfs from the Sloan Digital Sky Survey, we show that the fraction of active stars decreases as a function of vertical distance from the Galactic plane (a statistical proxy for age), and that the magnitude of this decrease changes significantly for different M spectral types. Adopting a simple dynamical model for thin disk vertical heating, we assign an age for the activity decline at each spectral type, and thus determine the activity lifetimes for M dwarfs. In addition, we derive a statistical age-activity relation for each spectral type using the dynamical model, the vertical distance from the Plane and the Hα emission line luminosity of each star (the latter of which also decreases with vertical height above the Galactic plane).