The dynamics of an evaporating droplet in an unsteady flow is of practical interest in many industrial applications and natural processes. To investigate the transport and evaporation dynamics of such droplets, we present a numerical study of an isolated droplet in an oscillating gas-phase flow. The study uses a one-way coupled two-phase flow model to assess the effect of the amplitude and the frequency of a sinusoidal external flow field on the lifetime of a multicomponent droplet containing a non-volatile solute dissolved in a volatile solvent. The results show that the evaporation process becomes faster with an increase in the amplitude or the frequency of the gas-phase oscillation. The liquid-phase transport inside the droplet also is influenced by the unsteadiness of the external gas-phase flow. A scaling analysis based on the response of the droplet under the oscillating drag force is subsequently carried out to unify the observed evaporation dynamics in the simulations under various conditions. The analysis quantifies the enhancement in the droplet velocity and Reynolds number as a function of the gas-phase oscillation parameters and predicts the effects on the evaporation rate.

Muskmelon, which is an important cucurbit of the tropical and subtropical region of the world, shows great diversity, with six different botanical or horticultural groups and fifteen varietal groups. In this study, a total of fifty (50) simple sequence repeat (SSR) markers were used to investigate the genetic diversity and population structure of 46 muskmelon accessions of different horticultural or varietal groups. Thirty-eight (38) of the fifty SSR markers were highly polymorphic. A total of 99 alleles were generated by the polymorphic markers, with an average of 2.06 alleles per loci. Heterozygosity among accessions for individual loci varied from 0.00 to 0.21, with the highest (0.21) reported for the CMCTN71 marker. The gene diversity and polymorphism information content (PIC) values varied between 0.08 to 0.72 and 0.07 to 0.67, with an average of 0.47 and 0.38, respectively. The primer that showed the highest gene diversity and PIC values was DM0913. The unweighted pair-group method for arithmetic average (UPGMA)-based dendrogram classified all the 46 accessions into two major clusters. Population structure analysis classified 46 muskmelon accessions into 2 subpopulations. The subpopulation I contained 29 accessions from the cantalupensis group, and subpopulation II contained 17 accessions from momordica, inodorus and conomon groups, respectively. Analysis of variance indicated that 18 and 68% of variance was due to subpopulations and differences among individuals, respectively. The present study supports the existence of sufficient variation among musk melon genetic resources in India, and their classification based on molecular markers will be helpful to accelerate the breeding programme for specific traits.

In automotive digital development, 3D prototype creation is a team effort of designers and engineers, each contributing with ideas and technical evaluations through means of computer simulations. To support the team in the 3D design ideation and exploration task, we propose an interactive design system for assisted design explorations and faster performance estimations. We utilize the advantage of deep learning-based autoencoders to create a low-dimensional latent manifold of 3D designs, which is utilized within an interactive user interface to guide and strengthen the decision-making process.

OBJECTIVES/GOALS: This presentation reports activities of a NCATS-funded collaborative working group created to promote dissemination and implementation (D&I) research within the CTSA landscape. Our working group seeks to meet both the conceptual as well as practical challenges to advancing the utilization of D&I across the translational science spectrum. METHODS/STUDY POPULATION: A fundamental focus of D&I is supporting the movement of effective health interventions into real-world use so that they benefit population health. Yet, this process remains unpredictable, with some interventions receiving widespread uptake in practice and others (of similar potential benefit) failing to translate. The value of research efforts is wasted when directed toward the “wrong” interventions. Recent discussion and experience amongst investigators in our collaborative working group has resulted in new ways of addressing this problem. Specifically, tools borrowed from business and management have shown promise in predicting which health interventions have the highest potential for commercialization and dissemination. RESULTS/ANTICIPATED RESULTS: We will conduct an environmental scan of CTSA hubs to understand their approaches to supporting commercialization and business development around research products, identifying the most promising and effective methods and processes. We will compile various tools for identifying and supporting interventions with the highest potential for commercialization, including how to form the multidisciplinary and stakeholder-engaged teams necessary to make these determinations. Finally, we will further explore the differences between patentable and non-patentable innovations and make recommendations for CTSAs in supporting the latter. DISCUSSION/SIGNIFICANCE: Commercialization of non-patentable interventions is an essential and underexplored element of the translational science spectrum. The perspectives and methods of D&I should not be relegated to late-stage translational steps, but rather inform the conduct of translational science writ large.

What effect did British imperialism in Myanmar have on frogs? And, given that the lives of these small amphibian creatures were rarely ever recorded or preserved in archival collections, how might we find out? Sceptical readers may also wish to take a step back and ask, why should historians even care about their lives? These are unusual questions for a historian to confront, but they are occasioned by the deepening conversation between ecology and history. This paper delves into the ecological impact of colonial rule in Myanmar through the lives of Burmese elephants and the creatures that they lived alongside. In it I argue that the concepts of ‘accumulation’ and ‘cascade’ are useful for enabling historians to apprehend the full extent of the impact of imperialism on the lives of animals.

In two dimensions, the problem governing a homogeneous phoretic swimmer of circular cross-section is ill-posed because of the logarithmic divergence associated with a purely diffusive solute transport. We address here the well-posed problem that is devised by introducing a slight inhomogeneity in the interfacial chemical activity. With the radial symmetry being perturbed, phoretic motion is animated by diffusio-osmosis. Solute advection, associated with that motion, becomes comparable to diffusion at large distances. The singular problem associated with that scale disparity is analysed using matched asymptotic expansions for arbitrary values of the Damköhler number $\textit {Da}$ and the intrinsic Péclet number $\textit {Pe}$. Asymptotic matching provides an implicit equation for the particle velocity in terms of these two parameters. The velocity exhibits a non-trivial dependence upon the sign $M$ of the slip coefficient. For $M=-1$, we observe the appearance of several solutions beyond a $\textit {Da}$-dependent critical value of $\textit {Pe}$. We also address the respective limits of small and large $\textit {Da}$ for fixed $\textit {Pe}$ and arbitrary inhomogeneity, and illuminate their linkage to the limit of weak inhomogeneity.

A field study was conducted to evaluate the effect of weed management practices in the main crop on growth, yield and economics of rice- ratoon rice cropping system in two consecutive years i.e., 2014–15 and 2015–16. The result showed that Cyperus difformis was the most dominant weed in the main rice crop, whereas Ludwigia adscendes was the dominant weed in ratoon rice. In weed-free plots, the main crop recorded the highest productivity of 47.52 kg/ha/day, whereas the ratoon crop registered productivity of 37.70 kg/ha/day which was the 79.3% of the main crop productivity. In the weedy plot, crop-weed competition caused 28.8 and 37.5% reduction in energy use efficiency and energy productivity of the rice-ratoon rice cropping system respectively. Yield reduction of 37.3 and 43.6% in the main crop and ratoon crop respectively recorded due to weed infestation in weedy check. All the weed control practices registered an increase in system productivity, nutrient uptake and energy use efficiency. Among the herbicidal treatments, application of bensulfuron-methyl + pretilachlor (60 + 600 g/ha) at 10 DAS to the main crop registered a higher net return of USD$ 639.2 and 260.1 of main crop and ratoon crop, respectively. Hence it can be recommended for weed management in rice-ratoon rice cropping system.

How do local citizens publicly converse online about the protests that follow when police kill Black residents? And do participants reflect local publics? Here we examine racial justice protests in Baton Rouge after police killed Alton Sterling in 2016. Local news streamed the protests on Facebook Live. In comments appearing below the video, locals supported and attacked each other in real-time while watching protests unfold. We assess a representative sample of these comments. First, we find surprising demographic and political representativeness in comments compared to census data and a local survey. We also document extensive hostile rhetoric corresponding with commenter traits and expressed views. Finally, we find more “likes” for comments by women, college-educated people, and locals. Violent and racially derogatory comments by Blacks received fewer likes, but similar comments by whites went unpenalized. The results illuminate social media functions in local politics, racial disparities in contentious digital dialogues, and political communication’s dual roles in strengthening and undermining multiracial democracy.

This work reports experimental observation and theoretical explanation of the dynamics and morphology of a droplet passing through a soap film. During the process, the film undergoes four sequential responses: (1) film deformation upon droplet impact; (2) drop–film detachment; (3) coalescence of the film shell with the drop; (4) peel-off of the film shell. Physical models and the corresponding analytical expressions are developed to reveal the underlying physics for the observed four responses. It is identified that the film is an elongated catenoid under continuous stretch by the droplet, and that they separate at the fixed height of 5.8 times of the droplet radius while the detach point is located at the centre of the height. After separation, the droplet is wrapped with a film shell, which is then punctured by the ring tip of the converging surface wave at the impacting Weber number range of [45, 225]. The film shell then coalesces with the droplet, falls off with a fixed velocity and is eventually ejected as a bubble leaving the droplet with a transplanted surface of the soap solution.

Air exchange between people has emerged in the COVID-19 pandemic as the important vector for transmission of the SARS-CoV-2 virus. We study the airflow and exchange between two unmasked individuals conversing face-to-face at short range, which can potentially transfer a high dose of a pathogen, because the dilution is small when compared to long-range airborne transmission. We conduct flow visualization experiments and direct numerical simulations of colliding respiratory jets mimicking the initial phase of a conversation. The evolution and dynamics of the jets are affected by the vertical offset between the mouths of the speakers. At low offsets the head-on collision of jets results in a `blocking effect', temporarily shielding the susceptible speaker from the pathogen carrying jet, although, the lateral spread of the jets is enhanced. Sufficiently large offsets prevent the interaction of the jets. At intermediate offsets (8-10 cm for 1 m separation), jet entrainment and the inhaled breath assist the transport of the pathogen-loaded saliva droplets towards the susceptible speaker's mouth. Air exchange is expected, in spite of the blocking effect arising from the interaction of the respiratory jets from the two speakers.

Let F be a Siegel cusp form of degree $2$ , even weight $k \ge 2$ , and odd square-free level N. We undertake a detailed study of the analytic properties of Fourier coefficients $a(F,S)$ of F at fundamental matrices S (i.e., with $-4\det (S)$ equal to a fundamental discriminant). We prove that as S varies along the equivalence classes of fundamental matrices with $\det (S) \asymp X$ , the sequence $a(F,S)$ has at least $X^{1-\varepsilon }$ sign changes and takes at least $X^{1-\varepsilon }$ ‘large values’. Furthermore, assuming the generalized Riemann hypothesis as well as the refined Gan–Gross–Prasad conjecture, we prove the bound $\lvert a(F,S)\rvert \ll _{F, \varepsilon } \frac {\det (S)^{\frac {k}2 - \frac {1}{2}}}{ \left (\log \lvert \det (S)\rvert \right )^{\frac 18 - \varepsilon }}$ for fundamental matrices S.