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1 - Folliculogenesis: From Preantral Follicles to Corpus Luteum Regression
from PART I - PHYSIOLOGY OF REPRODUCTION
- By Antonis Makrigiannakis, A. Rolaki
Edited by Botros R. M. B. Rizk, University of South Alabama, Juan A. Garcia-Velasco, Hassan N. Sallam, Antonis Makrigiannakis, University of Crete
Book: Infertility and Assisted Reproduction
Published online: 04 August 2010
Print publication: 15 September 2008, pp 3-9
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Summary

This chapter reports a variety of factors involved in the different stages of follicular development. Elucidation of the mechanisms that regulate follicular development may lead to the prevention of female reproductive disorders or other pathological conditions and to the development of new culture methods for oocytes for in vitro fertilization. Follicle-stimulating hormone (FSH) is considered to be the fundamental driver of folliculogenesis. Gonadotropins are even used in controlled ovarian stimulation (COS), which is an important component of assisted reproduction technology (ART). The main hormone product of the Corpus Luteum (CL) is progesterone, which induces the necessary endometrial modifications required for the acquisition of a receptive state, an anticipation of embryo implantation. If pregnancy does occur, regression must be inhibited since the CL is the main source of steroidogenesis, supporting the establishment and maintenance of a successful pregnancy.

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1 - Folliculogenesis: From Preantral Follicles to Corpus Luteum Regression

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1 - Folliculogenesis: From Preantral Follicles to Corpus Luteum Regression

Summary