The population of the recently-described Whenua Hou diving petrel Pelecanoides whenuahouensis comprises c. 200 adults that all breed in a single 0.018 km2 colony in a dune system vulnerable to erosion. The species would therefore benefit from the establishment of a second breeding population through a translocation. However, given the small size of the source population, it is essential that translocations are informed by carefully targeted monitoring data. We therefore modelled nest survival at the remaining population in relation to potential drivers (distance to sea and burrow density of conspecifics and a competitor) across three breeding seasons with varying climatic conditions as a result of the southern oscillation cycle. We also documented breeding phenology and burrow attendance, and measured chicks, to generate growth curves. We estimated egg survival at 0.686, chick survival at 0.890, overall nest survival at 0.612, and found no indication that nest survival was affected by distance to sea or burrow density. Whenua Hou diving petrels laid eggs in mid October, eggs hatched in late November, and chicks fledged in mid January at c. 86% of adult weight. Burrow attendance (i.e. feeds) decreased from 0.94 to 0.65 visits per night as chicks approached fledging. Nest survival and breeding biology were largely consistent among years despite variation in climate. Nest survival estimates will facilitate predictions about future population trends and suitability of prospective translocation sites. Knowledge of breeding phenology will inform the timing of collection of live chicks for translocation, and patterns of burrow attendance combined with growth curves will structure hand-rearing protocols. A tuhinga whakarāpopoto (te reo Māori abstract) can be found in the Supplementary material.

Life course research embraces the complexity of health and disease development, tackling the extensive interactions between genetics and environment. This interdisciplinary blueprint, or theoretical framework, offers a structure for research ideas and specifies relationships between related factors. Traditionally, methodological approaches attempt to reduce the complexity of these dynamic interactions and decompose health into component parts, ignoring the complex reciprocal interaction of factors that shape health over time. New methods that match the epistemological foundation of the life course framework are needed to fully explore adaptive, multilevel, and reciprocal interactions between individuals and their environment. The focus of this article is to (1) delineate the differences between lifespan and life course research, (2) articulate the importance of complex systems science as a methodological framework in the life course research toolbox to guide our research questions, (3) raise key questions that can be asked within the clinical and translational science domain utilizing this framework, and (4) provide recommendations for life course research implementation, charting the way forward. Recent advances in computational analytics, computer science, and data collection could be used to approximate, measure, and analyze the intertwining and dynamic nature of genetic and environmental factors involved in health development.

Glacier basal motion is responsible for the majority of ice flux on fast-flowing glaciers, enables rapid changes in glacier motion and provides the means by which glaciers shape alpine landscapes. In an effort to enhance our understanding of basal motion, we investigate the evolution of glacier velocity and ice-marginal lake stage on Kennicott Glacier, Alaska, during the spring–summer transition, a time when subglacial drainage is undergoing rapid change. A complicated record of > 50 m fill-and-drain sequences on a hydraulically-connected ice-marginal lake likely reflects the punctuated establishment of efficient subglacial drainage as the melt season begins. The rate of change of lake stage generally correlates with diurnal velocity maxima, both in timing and magnitude. At the seasonal scale, the up-glacier progression of enhanced summer basal motion promotes uniformity of daily glacier velocity fluctuations throughout the 10 km study reach, and results in diurnal velocity patterns suggesting increasingly efficient meltwater delivery to and drainage from the subglacial channel system. Our findings suggest the potential of using an ice-marginal lake as a proxy for subglacial water pressure, and show how widespread basal motion affects bulk glacier behavior.

A multichannel calorimeter system is designed and constructed which is capable of delivering single-shot and broad-band spectral measurement of terahertz (THz) radiation generated in intense laser–plasma interactions. The generation mechanism of backward THz radiation (BTR) is studied by using the multichannel calorimeter system in an intense picosecond laser–solid interaction experiment. The dependence of the BTR energy and spectrum on laser energy, target thickness and pre-plasma scale length is obtained. These results indicate that coherent transition radiation is responsible for the low-frequency component (${<}$1 THz) of BTR. It is also observed that a large-scale pre-plasma primarily enhances the high-frequency component (${>}$3 THz) of BTR.

Giant electromagnetic pulses (EMP) generated during the interaction of high-power lasers with solid targets can seriously degrade electrical measurements and equipment. EMP emission is caused by the acceleration of hot electrons inside the target, which produce radiation across a wide band from DC to terahertz frequencies. Improved understanding and control of EMP is vital as we enter a new era of high repetition rate, high intensity lasers (e.g. the Extreme Light Infrastructure). We present recent data from the VULCAN laser facility that demonstrates how EMP can be readily and effectively reduced. Characterization of the EMP was achieved using B-dot and D-dot probes that took measurements for a range of different target and laser parameters. We demonstrate that target stalk geometry, material composition, geodesic path length and foil surface area can all play a significant role in the reduction of EMP. A combination of electromagnetic wave and 3D particle-in-cell simulations is used to inform our conclusions about the effects of stalk geometry on EMP, providing an opportunity for comparison with existing charge separation models.

Radiocarbon dates from critical stratigraphic localities in southern British Columbia indicate that the growth history of the late Wisconsin Cordilleran Ice Sheet was different from that of most of the Laurentide Ice Sheet to the east. Much of southern British Columbia remained free of ice until after about 19,000 to 20,000 yr ago; only adjacent to the Coast Mountains is there a record of lowland glacier tongues in the interval 22,000 to 20,000 yr B.P. A major advance to the climax of late Wisconsin Cordilleran glacier ice in the northern States was not begun until after about 18,000 yr B.P. in the southwest of British Columbia and after about 17,500 yr B.P. in the southeast. The rate of glacier growth must have been very rapid in the two to three millennia prior to the climax, which has been dated in western Washington at shortly after 15,000 yr B.P.

Ancient history begins and ends with the ancient evidence. The evidence represents not only the foundation of the discipline, but the material out of which any argument must be built, and it is not possible to go further than it allows. This is part of the reason why the nature and value of the evidence for early Rome have long been, and remain, matters of considerable and sometimes contentious debate. The best evidence, simply because it is contemporary, is arguably the archaeological, but the sorts of questions that archaeological evidence can answer are often of little help when it comes to matters such as the politics and political structures of early Rome, which are the focus of this collection. For such matters, it is still necessary to work with the literary evidence. However, since the historical value of the literary evidence is so hotly contested, the uses to which that evidence is put and the conclusions that are drawn from it inevitably vary considerably. Despite more than a century of research, there is still nothing even remotely resembling a consensus on how the literary sources should best be handled. This paper explores some of the problems with the evidence for early Rome, considers something of the limits and uses of that evidence, as well as introduces the contributions that make up this collection of studies on power and politics in early Rome.

Glacier basal motion generates diurnal to multi-annual fluctuations in glacier velocity and mass flux. Understanding these fluctuations is important for prediction of future sea-level rise and for gaining insight into glacier physics and erosion. Here, we derive glacier velocity through cross-correlation of WorldView satellite imagery to document the evolution of ice surface velocity on Kennicott Glacier, Alaska, over the 2013 melt season. The summer speedup is spatially uniform over a ~12 km2 area, over which the spring velocity varies significantly. Velocity increases by 1.4-fold to tenfold across the study domain, with larger values where spring velocities are low. To investigate the cross-glacier distribution of basal motion required to explain the observed surface speedup, we employ a two-dimensional cross-sectional glacier flow model. We find the model is insensitive to the spatial distribution of basal slip because stress gradient ice coupling diffuses the surface expression of the basal velocity field. While the temporal evolution of the subglacial hydrologic system is critical for predicting a glacier's response to meltwater inputs, our work suggests that glacier and ice-sheet models do not require a detailed representation of subglacial hydrology to accurately capture the spatial pattern of glacier speedup.

The evidence underpinning the developmental origins of health and disease (DOHaD) is overwhelming. As the emphasis shifts more towards interventions and the translational strategies for disease prevention, it is important to capitalize on collaboration and knowledge sharing to maximize opportunities for discovery and replication. DOHaD meetings are facilitating this interaction. However, strategies to perpetuate focussed discussions and collaborations around and between conferences are more likely to facilitate the development of DOHaD research. For this reason, the DOHaD Society of Australia and New Zealand (DOHaD ANZ) has initiated themed Working Groups, which convened at the 2014–2015 conferences. This report introduces the DOHaD ANZ Working Groups and summarizes their plans and activities. One of the first Working Groups to form was the ActEarly birth cohort group, which is moving towards more translational goals. Reflecting growing emphasis on the impact of early life biodiversity – even before birth – we also have a Working Group titled Infection, inflammation and the microbiome. We have several Working Groups exploring other major non-cancerous disease outcomes over the lifespan, including Brain, behaviour and development and Obesity, cardiovascular and metabolic health. The Epigenetics and Animal Models Working Groups cut across all these areas and seeks to ensure interaction between researchers. Finally, we have a group focussed on ‘Translation, policy and communication’ which focusses on how we can best take the evidence we produce into the community to effect change. By coordinating and perpetuating DOHaD discussions in this way we aim to enhance DOHaD research in our region.

This paper focuses on the design of a cascade within a cold stream thrust reverser during the early, conceptual stage of the product development process. A reliable procedure is developed for the exchange of geometric and load data between a two dimensional aerodynamic model and a three dimensional structural model. Aerodynamic and structural simulations are carried out using realistic operating conditions, for three different design configurations with a view to minimising weight for equivalent or improved aerodynamic and structural performance. For normal operational conditions the simulations show that total reverse thrust is unaffected when the performance of the deformed vanes is compared to the un-deformed case. This shows that for the conditions tested, the minimal deformation of the cascade vanes has no significant affect on aerodynamic efficiency and that there is scope for reducing the weight of the cascade. The pressure distribution through a two dimensional thrust reverser section is determined for two additional cascade vane configurations and it is shown that with a small decrease in total reverse thrust, it is possible to reduce weight and eliminate supersonic flow regimes through the nacelle section. By increasing vane sections in high pressure areas and decreasing sections in low pressure areas the structural performance of the cascade vanes in the weight reduced designs, is improved with significantly reduced levels of vane displacement and stress.

We have examined the diagnostic significance of finding one band in the immunoglobulin (IgG) region in spinal fluid protein electrophoresis. From January 1983 to January 1986, 855 consecutive CSF electrophoreses were performed on as many patients. A blinded observer identified a single band in the IgG region in 53 cases (6.2%). In only 14 patients (26%), were the clinical features ultimately felt to be due to clinically definite or possible multiple sclerosis (MS). The majority of patients with a single band had another neurological diagnosis (55%) or were neurologically normal (6%). Many of the neurological disorders in which a single band was found were not disorders in which an increased intrathecal synthesis of immunoglobulin or electrophoretic restriction would have been expected. A variety of conditions can produce a single band pattern. The significance of these patterns and the means by which they might be identified are described.

In traditional transit timing variations (TTVs) analysis of multi-planetary systems, the individual TTVs are first derived from transit fitting and later modelled using n-body dynamic simulations to constrain planetary masses. We show that fitting simultaneously the transit light curves with the system dynamics (photo-dynamical model) increases the precision of the TTV measurements and helps constrain the system architecture. We exemplify the advantages of applying this photo-dynamical model to a multi-planetary system found in K2 data very close to 3:2 mean motion resonance, K2-19. In this case the period of the larger TTV variations (libration period) is much longer (>1.5 years) than the duration of the K2 observations (80 days). However, our method allows to detect the short period TTVs produced by the orbital conjunctions between the planets that in turn permits to uniquely characterise the system. Therefore, our method can be used to constrain the masses of near-resonant systems even when the full libration curve is not observed.

Epigenetic modifications to the genome are a key mechanism involved in the biological encoding of experience. Animal studies and a growing body of literature in humans have shown that early adversity is linked to methylation of the gene for the glucocorticoid receptor (GR), which is a key regulator of the hypothalamic–pituitary–adrenal axis as well as a broad range of physiological systems including metabolic and immune function. One hundred eighty-four families participated, including n = 74 with child welfare documentation of moderate-severe maltreatment in the past 6 months. Children ranged in age from 3 to 5 years, and were racially and ethnically diverse. Structured record review and interviews in the home were used to assess a history of maltreatment, other traumas, and contextual life stressors, and a composite variable assessed the number exposures to these adversities. Methylation of regions 1D, 1F, and 1H of the GR gene was measured via sodium bisulfite pyrosequencing. The composite measure of adversity was positively correlated with methylation at exons 1D and 1F in the promoter of the GR gene. Individual stress measures were significantly associated with a several CpG sites in these regions. GR gene methylation may be a mechanism of the biobehavioral effects of adverse exposures in young children.