Cross jurisdictional collaboration efforts and emergency vaccine plans that are consistent with Tribal sovereignty are essential to public health emergency preparedness. The widespread adoption of clearly written federal, state, and local vaccine plans that address fundamental assumptions in vaccine distribution to Tribal nations is imperative for future pandemic response.

The peristyle house kitchen in the legionary camp at Vindonissa is one of the few examples of a Mediterranean-style kitchen with a raised hearth in the northwestern provinces. The exceptional preservation of the kitchen made possible an interdisciplinary investigation combining archaeological, archaeobiological, and micromorphological analyses in order to reconstruct dietary and food-processing practices, kitchen maintenance, and waste disposal management in a 1st-c. CE legionary camp household in Germania Superior. The kitchen infrastructure, the large ceramic inventory, and the amphorae finds together indicate a sophisticated cuisine and also food preparation for a large number of people, most likely by servants. The archaeobiological finds provide evidence that the diet was strongly Roman influenced and luxurious. These results confirm that the diet and in general the whole lifestyle of military members was strongly determined by military rank. The house was most likely inhabited by a high-ranking officer of the 11th legion.

The purpose of this experiment was to investigate the welfare of pregnant mares kept in straight stalls and given only limited exercise, conditions that are similar to those encountered in the pregnant mare urine industry. Sixteen pregnant mares (eight in each of two years) were randomly assigned to two groups: Ex (exercised in a paddock for 30 min per day) or NoEx (exercised for one 30 min period every 14 days). The horses were housed in straight (or ‘tie’) stalls for six months and had ad libitum access to grass hay. Each horse's behaviour was recorded on videotape once per week for 24 h. The major behaviours were eating hay, standing, and stand-resting (head down and one hind limb flexed). There was no difference between the behaviours or the number of foot lifts per min of the Ex and NoEx groups in their stalls. Nine of 16 mares were not observed in recumbency throughout the whole of the six-month observation period, suggesting that horses with no previous experience in straight stalls may be reluctant to lie down. Thirteen of 16 mares dropped to their knees at least once, probably when they were REM sleeping while standing. There were no significant differences between the Ex and the NoEx mares in baseline plasma Cortisol levels or in Cortisol response to ACTH. Following 30 min of exercise, NoEx mares showed an increase in Cortisol from 5.0 to 5.4 μg dL−1, whereas Ex mares showed a decrease from 4.6 to 3.6 µg dL−1. The NoEx horses that had been confined for two weeks trotted more (NoEx = 22 [6-38; median and range]% of time; Ex = 2.4 [0-8.7]%) and galloped more (NoEx = 6 [2-8]%; Ex = 0 [0-4]%) than the Ex that were released daily, but walked less (NoEx = 17 [10-26]%; Ex = 35 [20-40]%) and grazed less (NoEx = 0%; Ex = 3 [0-12]%). Confined horses show rebound locomotion — that is, a compensatory increase — when released from confinement, indicating a response to exercise deprivation.

In this interview, Tom Erbe reflects on his three decades as a developer of computer music software and hardware, both freeware and commercial. Tom met with Theodore Gordon on 8 December 2021 and discussed the beginnings of SoundHack and its roots in experimental music studio practice and hacker culture, ideas behind the design of sound processor interface and the shift from experimental software development to Eurorack modular hardware design.

For slightly more than 30 years I have been developing audio software and hardware under the moniker soundhack. Through these years I have programmed applications, plugins, externals, hardware and Eurorack modules – usually focusing on signal processing techniques and applications that are not easily available or offered by mainstream software companies. In this article, I would like to share my point of view and relate the rationale behind the development of these tools, my evolving sonic and design aesthetic, and some of the advantages, disadvantages and other differences between the the various hardware and software contexts.

Discussions of spatial relationships are persistent features of research on the organization of craft production. Despite the centrality of spatial issues, the correspondence between spatial patterning and economic organization remains relatively under-theorized, especially around questions of power and control. Drawing from the literature on craft ecology, specialization and landscape archaeology, I develop an approach that considers spatial scales of patterning, the power projection of elites and institutions and the articulation between elements of the crafting landscape. This approach recognizes the complex sets of factors affecting spatial patterning and ultimately produces a more robust understanding of how ancient economic systems were organized. These ideas are explored through a case study on Late Bronze and Early Iron Age metal production in the Caucasus, clarifying the organizational logics of the metal economy and highlighting how this industry differed in significant ways from other contemporary metal-producing regions in the ancient Near East.

The aim of the present study was to compare the cerebral activation associated with encoding and retrieval in individual subjects with the average activation in the same group of subjects. Twelve volunteers performed two paradigms: 1) intentional encoding of words, and 2) recognition of learned words intermixed with new distracters. Echo-planar magnetic resonance imaging (MRI) of BOLD signal changes was used to compare cerebral activation between active and resting conditions. During encoding, activation of the left precentral gyrus related to the motor response was observed in some subjects. Averaged data showed increased activation of the left precentral gyrus, the supplementary motor area (SMA), the left inferior frontal gyrus and in the left temporo-occipital junction. During recognition, motor response-related activity was found in the precentral cortex and SMA in most subjects. Activation in other brain areas showed considerable interindividual variation. In the entire group, recognition showed activation of the left dorsolateral prefrontal cortex, the precentral gyrus, the SMA, and the temporo-occipital junction. The total amount and the distribution of task-related cerebral activation varies considerably between individuals and might correspond to individual preferences of cognitive strategies. The investigation of these interindividual variations will be an exciting scientific challenge in the near future.

Objectives. – Studies on the relation between local cerebral activation and retrieval success usually compared high and low performance conditions, and thus showed performance-related activation of different brain areas. Only a few studies directly compared signal intensities of different response categories during retrieval. During verbal recognition, we recently observed increased parieto-occipital activation related to false alarms. The present study intends to replicate and extend this observation by investigating common and differential activation by veridical and false recognition.

Methods. – Fifteen healthy volunteers performed a verbal recognition paradigm using 160 learned target and 160 new distracter words. The subjects had to indicate whether they had learned the word before or not. Echo-planar MRI of blood-oxygen-level-dependent signal changes was performed during this recognition task. Words were classified post hoc according to the subjects’ responses, i.e. hits, false alarms, correct rejections and misses. Response-related fMRI-analysis was used to compare activation associated with the subjects’ recognition success, i.e. signal intensities related to the presentation of words were compared by the above-mentioned four response types.

Results. – During recognition, all word categories showed increased bilateral activation of the inferior frontal gyrus, the inferior temporal gyrus, the occipital lobe and the brainstem in comparison with the control condition. Hits and false alarms activated several areas including the left medial and lateral parieto-occipital cortex in comparison with subjectively unknown items, i.e. correct rejections and misses. Hits showed more pronounced activation in the medial, false alarms in the lateral parts of the left parieto-occipital cortex.

Conclusions. – Veridical and false recognition show common as well as different areas of cerebral activation in the left parieto-occipital lobe: increased activation of the medial parietal cortex by hits may correspond to true recognition, increased activation of the parieto-occipital cortex by false alarms may correspond to familiarity decisions. Further studies are needed to investigate the reasons for false decisions in healthy subjects and patients with memory problems.

The south-eastern Black Sea area is a key region for understanding the history of iron metallurgy. While Classical texts mention the people living in this area as producers, and perhaps even inventors, of iron, material evidence has been lacking. Recent archaeological survey and scientific analyses now make it possible to investigate iron technologies in the region during the mid to late first millennium BC and the medieval period, providing new insights into the metallurgical tradition that inspired such admiration in the Graeco-Roman world. These results have implications for the smelting of iron in liquid state, although it remains unclear where and when this technology first appeared in Western Eurasia.

The South Caucasus has been largely absent in broader discussions of prehistoric population aggregation in Greater Eurasia. The authors use remote sensing, surface collection and magnetometry to investigate two hilltop fortress settlements at the margins of the Kura River Basin, with a particular emphasis on satellite settlements around the main hills. The results support a model of settlement growth in which previously mobile groups settled around the fortress, while maintaining a degree of spatial and social separation. The use of multiple survey techniques reveals a complex picture of settlement organisation, with implications for comparative analysis of prehistoric population aggregation models.