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33B - Uterus Transplantation Is a Step Too Far

Against

from Section V - Ethics and Statistics

Published online by Cambridge University Press:  25 November 2021

Roy Homburg
Affiliation:
Homerton University Hospital, London
Adam H. Balen
Affiliation:
Leeds Centre for Reproductive Medicine
Robert F. Casper
Affiliation:
Mount Sinai Hospital, Toronto
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Summary

Uterus transplantation (UTx) is the first available treatment for absolute uterine factor infertility (AUFI), which is caused by absence of a uterus or presence of a non-functional uterus. Women with AUFI may in a limited number of countries achieve genetic motherhood by gestational surrogate carrier arrangements, and after adoption from the birth-giving mother, also obtain legal motherhood. However, gestational surrogacy is non-approved in a vast majority of countries/societies of the world because of ethical, legal and/or religious reasons. Thus, gestational surrogacy is not an available option for most women with AUFI.

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Chapter
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Publisher: Cambridge University Press
Print publication year: 2021

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References

Brännström, M, Johannesson, L, Bokström, H, et al. Livebirth after uterus transplantation. Lancet. 2015;14:607–16.Google Scholar
Ejzenberg, D, Andraus, W, Baratelli Carelli Mendes, LR, et al. Livebirth after uterus transplantation from a deceased donor in a recipient with uterine infertility. Lancet. 2019;392:2697–704.Google Scholar
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Järvholm, S, Kvarnström, N, Dahm-Kähler, P, Brännström, M. Donor´s health-related quality-of-life and psychosocial outcomes 3 years after uterus donation for transplantation. Hum Reprod. 2019;34:1270–7.CrossRefGoogle ScholarPubMed
Järvholm, S, Johannesson, L, Clarke, A, Brännström, M. Uterus transplantation trial: psychological evaluation of recipients and partners during the post-transplantation year. Fertil Steril. 2015;104:1010–15.CrossRefGoogle ScholarPubMed
Milliez, J. Uterine transplantation FIGO committee for the ethical aspects of human reproduction and women’s health. Int J Gynaecol Obstet. 2009;106:270.CrossRefGoogle ScholarPubMed
McCulloch, P, Altman, DG, Campbell, WB, et al. No surgical innovation without evaluation: the IDEAL recommendations. Lancet. 2009;374:1105–12.CrossRefGoogle ScholarPubMed

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