Skip to main content Accessibility help
×
Hostname: page-component-7c8c6479df-ws8qp Total loading time: 0 Render date: 2024-03-28T14:52:55.979Z Has data issue: false hasContentIssue false

Chapter 19 - Cerebral microbleeds and antithrombotictreatment

from Section 3 - Microbleeds in relation to specific populations, diseases and neurological symptoms

Published online by Cambridge University Press:  05 July 2011

David J. Werring
Affiliation:
Institute of Neurology, London
Get access

Summary

Cerebral microbleeds (CMBs), detected by MRI gradient-recalled echo (GRE) sequences, are increasingly recognized as a potential radiological predictor for massive symptomatic intracerebral hemorrhage (ICH). The possible association between antithrombotic drug exposure and presence of CMBs is potentially confounded by the indications for which the drugs are prescribed. As CMBs may be related to the presence of cardiovascular and cerebrovascular diseases in general, antithrombotic drugs may be more often prescribed to persons with an increased risk of developing CMBs unrelated to the use of antithrombotic agents. In non-cardioembolic ischemic stroke, antiplatelet agents remain the mainstay of treatment for secondary stroke prevention. In general, aspirin is considered as a safe antiplatelet agent for ischemic stroke, carrying only a 1% risk of symptomatic ICH. Anticoagulation with warfarin remains the most effective prevention for cardioembolic stroke related to atrial fibrillation; in randomized clinical trials, warfarin reduced the relative risk of stroke by 60-70%.
Type
Chapter
Information
Cerebral Microbleeds
Pathophysiology to Clinical Practice
, pp. 165 - 172
Publisher: Cambridge University Press
Print publication year: 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×